Results 71 to 80 of about 4,302 (241)

Studies on the Degradation of Pterine and Pterine-6-carboxylic Acid by Pseudomonas fluorescens UK-1. [PDF]

Acta Chemica Scandinavica, 1975
Pseudomonas fluorescens UK-1 has been incubated in basal mineral medium which was 0.5mM in pterine or pterine-6-carboxylic acid. During incubation the test organism splits the pteridine ring by liberating carbon dioxide from position 2. Glucose added to the medium greatly enhances both the growth of the organism and the carbon dioxide formation ...
Juhani Soini, Anita Backman, Jan Rosenblom, Anna-Britta Hörnfeldt, Rolf Servin, Hans Sternerup   +5 more
openaire   +3 more sources

Robust Self‐Healing Metallo‐Supergels of Folic Acid: Potential Sustainable Gelator for Oilfield Applications

Chemistry – A European Journal, Volume 31, Issue 25, May 5, 2025.
In combination with a large group of various metal salts folic acid (FA) forms mechanically robust metallogels with rapid recovery and self‐healing properties. These versatile gel systems provide tunable stiffness, with up to 95% of stiffness restored within 1 min.
Mahya Asgharian Marzabad, Subhasis Chattopadhyay, Sami Hietala, Nonappa Nonappa, Radek Marek, Ondřej Jurček   +5 more
wiley   +1 more source

Patients with Allan‐Herndon‐Dudley Syndrome (MCT8 Deficiency) Display Symptoms of Parkinsonism in Childhood and Respond to Levodopa/Carbidopa Treatment

Movement Disorders, Volume 40, Issue 5, Page 938-949, May 2025.
Abstract Background Patients with mutations in the monocarboxylate transporter 8 (MCT8, SLC16A2) suffer from X‐linked recessive Allan‐Herndon‐Dudley syndrome (AHDS), which is characterized by developmental delay and a severe movement disorder. Current trials using thyroid hormone derivatives to overcome the transporter defect have failed to achieve ...
Nina‐Maria Wilpert, Angela L. Hewitt, Roser Pons, Marie‐Thérèse Henke, Andrea Dell'Orco, Martin Bauer, Christiane Grolik, Stephan Menz, Monika Wahle, Annika Zink, Alessandro Prigione, Christina Reinauer, Catharina Lange, Christian Furth, Knut Brockmann, Sabine Jung‐Klawitter, Stine Christ, Angela M. Kaindl, Anna Tietze, Heiko Krude, Thomas Opladen, Markus Schuelke   +21 more
wiley   +1 more source

A concise treatment of pterins: some recent synthetic and methodology aspects and their applications in molecular sensors

Pteridines, 2018
A concise account of pterins in chemistry and biology and their applications in molecular sensors including their optical spectroscopic properties are described.
Goswami Shyamaprosad, Das Manas Kumar, Sain Dibyendu, Goswami Bhaswati   +3 more
doaj   +1 more source

Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays

Molecules, 2019
Pteridine reductase 1 (PTR1) is a trypanosomatid multifunctional enzyme that provides a mechanism for escape of dihydrofolate reductase (DHFR) inhibition. This is because PTR1 can reduce pterins and folates.
Magambo Phillip Kimuda, Dustin Laming, Heinrich C. Hoppe, Özlem Tastan Bishop   +3 more
doaj   +1 more source

Molecular Insights Into MR1‐Mediated T Cell Immunity: Lessons Learned and Unanswered Questions

Immunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT The major histocompatibility complex class‐I related protein, MR1, is an evolutionarily conserved antigen presenting molecule that binds and displays organic metabolites to T cells, including mucosal associated invariant T (MAIT) cells and diverse MR1‐restricted T cells (MR1T). Structural studies have elucidated how MR1 can accommodate a range
Wael Awad, Mohamed R. Abdelaal, Victoria Letoga, James McCluskey, Jamie Rossjohn   +4 more
wiley   +1 more source

Dual‐Cys bacteriophytochromes: intermediates in cyanobacterial phytochrome evolution?

The FEBS Journal, Volume 292, Issue 5, Page 1197-1216, March 2025.
Phytochromes, light‐induced reversible photoreceptors in plants, algae, and bacteria, have a Cys residue in either the GAF or ‘PAS‐knot’ regions for linear tetrapyrrole linkage. Newly discovered dual‐Cys bacteriophytochromes (DCBs) with Cys in both GAF and ‘PAS‐knot’ in oxygenic photosynthetic cyanobacteria are plausible intermediates in the evolution ...
Hee Wook Yang, Ji‐Young Song, Ji‐Joon Song, Young Won Kim, Nathan C. Rockwell, Woojin Kim, Hyunsoo Kim, J. Clark Lagarias, Youn‐Il Park   +8 more
wiley   +1 more source

Melanin and Neurotransmitter Signalling Genes Are Differentially Co‐Expressed in Growing Feathers of White and Rufous Barn Owls

Pigment Cell &Melanoma Research, Volume 38, Issue 2, March 2025.
The colouration of the ventral face of barn owls varies from white to rufous, depending on the MC1R (V126I) genotype. This colouration is linked to multiple fitness and behavioural traits. Genes linked to neurotransmitters and synapses are upregulated with melanin genes in a transcriptome of growing feathers from the ventral part of chicks of the ...
Anne‐Lyse Ducrest, Luis M. San‐Jose, Samuel Neuenschwander, Emanuel Schmid‐Siegert, Céline Simon, Marco Pagni, Christian Iseli, Hannes Richter, Nicolas Guex, Tristan Cumer, Emmanuel Beaudoing, Mélanie Dupasquier, Pauline Charruau, Pauline Ducouret, Ioannis Xenarios, Jérôme Goudet, Alexandre Roulin   +16 more
wiley   +1 more source

Gut microbiome and metabolome characteristics of patients with cholesterol gallstones suggest the preventive potential of prebiotics

iMeta, Volume 4, Issue 1, February 2025.
Alterations in gut microbial composition and fecal metabolome have been reported in patients with gallstones. The gut microbiota plays a crucial role in shaping the host's fecal metabolic profile. Specifically, metabolites of amino acids, fatty acids, and nicotinic acid may affect the synthesis, transport, or metabolism of cholesterol, thereby ...
Ye Liu, Hexin Li, Tianhan Sun, Gaoyuan Sun, Boyue Jiang, Meilan Liu, Qing Wang, Tong Li, Jianfu Cao, Li Zhao, Fei Xiao, Fangqing Zhao, Hongyuan Cui   +12 more
wiley   +1 more source

Phylogenetic and Functional Diversity of Soluble Di‐Iron Monooxygenases

Environmental Microbiology, Volume 27, Issue 2, February 2025.
Relationships between monooxygenase substrates and products with respect to host cell physiology and biotechnology applications. ABSTRACT Monooxygenase (MO) enzymes are responsible for the oxidation of hydrocarbons and other compounds in the carbon and nitrogen cycles, are important for the biodegradation of pollutants and can act as biocatalysts for ...
Sui Nin Nicholas Yang, Michael A. Kertesz, Nicholas V. Coleman   +2 more
wiley   +1 more source