Puerarin Alleviates Neuropathic Pain by Inhibiting Neuroinflammation in Spinal Cord
Neuropathic pain responds poorly to drug treatments, and partial relief is achieved in only about half of the patients. Puerarin, the main constituent of Puerariae Lobatae Radix, has been used extensively in China to treat hypertension and tumor.
Ming Liu +5 more
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3′-5′-cyclic adenosine monophosphate (cAMP) is a signaling messenger produced in response to the stimulation of cellular receptors, and has a myriad of functional applications depending on the cell type.
Bhogal, NK, Gorelik, J, Hasan, A
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Puerarin, a bioactive isoflavone extracted from Pueraria lobata, possesses well-documented pharmacological properties, including anti-inflammatory, antioxidant, and metabolic regulatory effects, which have been extensively studied in mammalian models and
Yi Huang +5 more
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Oxidative Stress and Parkinson's Disease: New Hopes in Treatment with Herbal Antioxidants [PDF]
Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology.
Bahmani, Mahmoud. +3 more
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Protective activity of kudzu (Pueraria thunbergiana) vine on chemically-induced hepatotoxicity: in vitro and in vivo studies [PDF]
Bo Yoon Chang +5 more
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Enzymatic galactosylation of phenolic compounds by permeabilized cells of Pantoea anthophila. [PDF]
Briceño JR +6 more
europepmc +1 more source
The anti-osteoporotic effect of puerarin on the femoral bone in rat models of osteoporosis: a systematic review and meta-analysis. [PDF]
Yang Z, Tang R, Ma Y, Luo W, Hu Y.
europepmc +1 more source
Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin. [PDF]
Xi SY +9 more
europepmc +1 more source
Characterization of the initial degradation mechanism involved in <i>C</i>-glycosylated isoflavone puerarin in soil microorganism. [PDF]
Kumano T +5 more
europepmc +1 more source
Ruminal Degradation of Puerarin and Its Effects on In Vitro Ruminal Fermentation, Methane Emission, and Microbial Community Structure. [PDF]
Guo X +11 more
europepmc +1 more source

