Results 11 to 20 of about 8,591 (223)

Effect of puerarin on human choriocarcinoma cells

open access: yesOpen Medicine, 2015
Objective: To discuss the effect of puerarin on human choriocarcinoma cells. Methods: Survival rates under puerarin monotherapy, fluorouracil (5-FU) monotherapy and puerarin in combination with 5-FU were detected by MTT assay.
Bao Lidao   +5 more
doaj   +3 more sources

Metabolic profile of puerarin in rats after intragastric administration of puerarin solid lipid nanoparticles

open access: yesInternational Journal of Nanomedicine, 2013
Cheng-Feng Luo,1,2 Ning Hou,2,3 Juan Tian,1,2 Mu Yuan,2,3 Shi-Ming Liu,1,2 Long-Gen Xiong,1,2 Jian-Dong Luo,2,3 Min-Sheng Chen1,2,41The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China; 2Guangzhou ...
Luo CF   +7 more
doaj   +6 more sources

Puerarin Targets MIC19 to Suppress Mitochondrial Metabolism of Tumor-Infiltrating Tregs and Enhance Anti-tumor Immunity. [PDF]

open access: yesAdv Sci (Weinh)
Puerarin targets mitochondrial MIC19 in tumor‐infiltrating Tregs, impairing their immunosuppressive function and enhancing antitumor immunity. This study uncovers the metabolic dependency of tumor‐infiltrating Tregs and highlights a potential metabolic‐targeted immunotherapeutic strategy for liver cancer. Abstract Regulatory T cells (Tregs) are pivotal
Li Y   +10 more
europepmc   +2 more sources

Lignin/Puerarin Nanoparticle-Incorporated Hydrogel Improves Angiogenesis through Puerarin-Induced Autophagy Activation

open access: yesInternational Journal of Nanomedicine, 2023
Puerarin is the main isoflavone extracted from Radix Puerariae lobata (Willd.) and exerts a strong protective effect on endothelial cells. This isoflavone also exerts proven angiogenic effects; however, the potential underlying mechanism has not been fully explored.
Yingjing Pan   +8 more
openaire   +4 more sources

Puerarin for Acute Ischemic Stroke [PDF]

open access: yesStroke, 2004
Puerarin, a form of herbal medicine, is widely used in the treatment of acute ischaemic stroke in China.To assess the efficacy and safety of puerarin in patients with acute ischaemic stroke.We searched the Cochrane Stroke Group Trials Register (last searched August 2006), the Trials Register of the Cochrane Complementary Medicine Field (last searched ...
Y, Tan, M, Liu, B, Wu
openaire   +2 more sources

Effect of puerarin on bone formation [PDF]

open access: yesOsteoarthritis and Cartilage, 2007
Puerarin is one of the major phytoestrogens isolated from Pueraria lobata, a Chinese medicine known as Gegen. Our laboratory compared the amount of new bone produced by puerarin in collagen matrix (carrier) to that produced by the collagen matrix alone.Eighteen bone defects, 5mm by 10mm were created in the parietal bone of nine New Zealand White ...
Rabie, B, Wong, R
openaire   +4 more sources

Puerarin: A Potential Therapeutic for SARS-CoV-2 and Hantavirus Co-Infection

open access: yesFrontiers in Immunology, 2022
Patients with Hantavirus-caused epidemic hemorrhagic fever (EHF) are at risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is currently no validated EHF/SARS-CoV-2 strategy.
Weizheng Liang   +12 more
doaj   +1 more source

Modulation of neurotrophic signaling pathways by polyphenols [PDF]

open access: yes, 2015
Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza   +3 more
core   +1 more source

Quantification of Solvent Contribution to the Stability of Noncovalent Complexes [PDF]

open access: yes, 2013
We introduce an indirect approach to estimate the solvation contributions to the thermodynamics of noncovalent complex formation through molecular dynamics simulation.
Hetényi, Csaba   +3 more
core   +1 more source

Cardioprotective Effects of Puerarin-V on Isoproterenol-Induced Myocardial Infarction Mice Is Associated with Regulation of PPAR-Υ/NF-κB Pathway

open access: yesMolecules, 2018
Puerarin is a well-known traditional Chinese medicine which has been used for the treatment of cardiovascular diseases. Recently, a new advantageous crystal form of puerarin, puerarin-V, has been developed.
Xuguang Li   +8 more
doaj   +1 more source

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