Results 151 to 160 of about 113,584 (291)

PUFA und Atopie [PDF]

Allergo Journal, 2004
openaire   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

PUFAs in sickle cell disease [PDF]

The American Journal of Clinical Nutrition, 2013
openaire   +2 more sources

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, EarlyView.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Incretin and Glucagon Signalling in MASLD and MASH: Integrating Metabolic Pathways With Disease Progression

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) arises from dysregulated interactions between nutrient delivery, adipose tissue lipid handling and liver lipid metabolism, which collectively coalesce to drive inflammatory signalling leading to metabolic dysfunction‐associated steatohepatitis (MASH) and fibrosis. Recent clinical
Evangelia E. Tsakiridis, Gregory R. Steinberg   +1 more
wiley   +1 more source

Flooding affects fluctuating asymmetry but not growth of a riparian orbweaving spider

Ecological Entomology, EarlyView.
In a mesocosm experiment we assessed the impact of flood on aquatic insect emergence and on spider development using geometric morphometric analysis of fluctuating asymmetry. We observed 45% higher emergence in flooded mesocosm throughout the season. Spiders did not grow bigger but exhibited ~15% lower fluctuating asymmetry than in controls.
Stephane Mutel, Martin H. Entling, Ken M. Mauser, Federica Spani, Celia Thomas, Collins Ogbeide, Mirco Bundschuh, Franziska Fiolka, Franziska Middendorf, Ralf Schulz, Alessandro Manfrin   +10 more
wiley   +1 more source

The Injection of Lipids Into Yolk Sac has Been Shown to Alter the Lipid Metabolism of Adult Nile Tilapia (<i>Oreochromis niloticus</i>). [PDF]

Aquac Nutr
Luo L, Thongchaitriwat S, Kumkhong S, Kiatmontri J, Yang S, Panserat S, Boonanuntanasarn S.   +6 more
europepmc   +1 more source

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Deficiency of vital organic nutrients in ecosystems limits brain development and fitness in wild fish. [PDF]

J Exp Biol
Závorka L, Höjesjö J, Auer S, Austad B, Dionigi F, Hansson P, Killen SS, Mari S, Olsen E, Pilecky M, Pinter K, Polonyiová A, Stehlík P, Smagul T, Vitecek S, Yegon MJ, Němec P.   +16 more
europepmc   +1 more source