Results 311 to 320 of about 114,514 (356)
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Clinical Nutrition, 2017
BACKGROUND & AIMS Currently there is no FDA-approved therapy for nonalcoholic steatohepatitis (NASH). Increased n-6/n-3 polyunsaturated fatty acids (PUFA) ratio can induce endoplasmic reticulum (ER) stress and mitochondrial dysfunction that characterize ...
L. S. R. R. Okada +10 more
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BACKGROUND & AIMS Currently there is no FDA-approved therapy for nonalcoholic steatohepatitis (NASH). Increased n-6/n-3 polyunsaturated fatty acids (PUFA) ratio can induce endoplasmic reticulum (ER) stress and mitochondrial dysfunction that characterize ...
L. S. R. R. Okada +10 more
semanticscholar +1 more source
Microalgae as a Source for VLC-PUFA Production.
Sub-cellular biochemistry, 2016Microalgae present a huge and still insufficiently tapped resource of very long-chain omega-3 and omega-6 polyunsaturated fatty acids (VLC-PUFA) for human nutrition and medicinal applications. This chapter describes the diversity of unicellular eukaryotic microalgae in respect to VLC-PUFA biosynthesis.
I. Khozin‐Goldberg +2 more
semanticscholar +3 more sources
Whole‐body utilization of n−3 PUFA in n−6 PUFA‐deficient rats
Lipids, 2003AbstractWe evaluated the utilization of α‐linolenic acid (18∶3n−3) in growing rats consuming a diet deficient in n−6 PUFA. After 90 d, whole‐body 18∶3n−3 accumulation was 55% lower, total n−3 PUFA accumulation was 21% lower, and 18∶3n−3 disappearance was 14% higher in n−6 PUFA‐deficient rats.
Richard P, Bazinet +2 more
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n−3 PUFAs in cardiovascular disease
International Journal of Cardiology, 2013Many large, randomised clinical trials and some meta-analyses have shown that treatment with n-3 polyunsaturated fatty acids (n-3 PUFAs) is associated with consistent benefits on cardiovascular (CV) events, primarily due to a reduction of coronary and CV deaths in patients with coronary heart disease.
Roberto, Marchioli, Giacomo, Levantesi
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Correlation between PUFA/pufa scores and BMI-for age in rural Indian children
Indian Journal of Oral Sciences, 2014Context: Dental caries continues to be a major health problem in the developing nations like India. The unmet dental care needs pose an important risk factor for undernutrition prevalence in rural areas. Aims: The present study aimed to investigate the effect of dental caries and its consequences using pulp involvement, ulceration, fistula, abscess ...
Devinderjit Kaur +3 more
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PUFA for Human Health: Diet or Supplementation?
Current Pharmaceutical Design, 2009Large doses of omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are used to treat several diseases including hypertriglyceridemia in humans. Modest levels of EPA and DHA may be obtained from food, particularly from fatty fish.
ABETE P +5 more
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International Journal of Cardiology, 2013
The risk of death of patients with heart failure (HF) is still too high in daily clinical practice despite the many progress that have occurred in the diagnosis and treatment of this syndrome that significantly reduce the mortality of these patients.
Roberto, Marchioli, Giacomo, Levantesi
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The risk of death of patients with heart failure (HF) is still too high in daily clinical practice despite the many progress that have occurred in the diagnosis and treatment of this syndrome that significantly reduce the mortality of these patients.
Roberto, Marchioli, Giacomo, Levantesi
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n-3 Pufas and Cardiovascular Disease Prevention
Future Cardiology, 2010Today, there are several observational and experimental studies, especially clinical randomized trials, that have proven the beneficial effects of n-3 polyunsaturated fatty acids (PUFAs). The most compelling evidence for the cardiovascular benefits of n-3 PUFAs comes from studies of primary prevention in patients following myocardial infarction, and ...
MANERBA, Alessandra +3 more
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PUFAs and Their Metabolites in Carcinogenesis
2020DNA damage due to endogenous and exogenous agents leads to activation of oncogenes. To prevent the activation of oncogenesis, there are many endogenous DNA repair mechanisms. But less well-known is the observation that essential fatty acids and their metabolites participate in mutagenesis and carcinogenesis.
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