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PUFA, genotypes and risk for cardiovascular disease.
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2021Polyunsaturated fatty acids (PUFAs) are long chain fatty acids that are characterized by the presence of more than one double bond. These include fatty acids such as ꞷ-3-α-linolenic acid (ALA) and ꞷ-6 -linoleic acid (LA) which can only be obtained from ...
Chinmayee Panda +2 more
semanticscholar +3 more sources
FEMS Microbiology Letters, 2020
The discovery of non-fish sources of polyunsaturated fatty acids (PUFAs) is of great biotechnological importance. Although various oleaginous microalgae and fungi are able of accumulating storage lipids (single cell oils-SCOs) containing PUFAs, the ...
Maria Kothri +5 more
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The discovery of non-fish sources of polyunsaturated fatty acids (PUFAs) is of great biotechnological importance. Although various oleaginous microalgae and fungi are able of accumulating storage lipids (single cell oils-SCOs) containing PUFAs, the ...
Maria Kothri +5 more
semanticscholar +1 more source
Red blood cell PUFAs reflect the phospholipid PUFA composition of major organs.
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2016Numerous clinical trials examining the use of omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFAs) on various health outcomes have been conducted, and fish oil remains one of the most widely used nutritional supplements. More recently, studies have begun to utilize the omega-3 index, defined as the sum of EPA+DHA in red blood cells (RBCs), as ...
J. Fenton +3 more
semanticscholar +3 more sources
Long‐chain PUFA supplementation improves PUFA profile in infants with cholestasis
Lipids, 2002AbstractLong‐chain PUFA (LCP) deficiency is a frequent complication in cholestatic infants. We investigated the effects of LCP‐supplemented formula on EFA status in infants with cholestasis. Twenty‐three infants with cholestasis (biliary atresia after surgery, 8; intrahepatic cholestasis, 15) aged 1.9 to 4.9 mon (median 3.1 mon) were randomized to ...
Piotr, Socha +7 more
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PUFA for Prevention and Treatment of Dementia?
Current Pharmaceutical Design, 2009Polyunsaturated fatty acids (PUFA) play a crucial role in cerebral structure and function. Omega-3 PUFA is an exciting area of research, with docosahexaenoic acid (DHA) emerging as a new potential agent for prevention of cognitive decline and treatment of Alzheimer's disease.
I, Carrié +4 more
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Prostaglandins & other lipid mediators, 2019
Notwithstanding the ongoing debate on their full potential in health and disease, there is general consensus that n-3 PUFAs play important physiological roles.
Ian de Bus +4 more
semanticscholar +1 more source
Notwithstanding the ongoing debate on their full potential in health and disease, there is general consensus that n-3 PUFAs play important physiological roles.
Ian de Bus +4 more
semanticscholar +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2010
Excess lipid accumulation in nonadipose tissues may occur in the setting of high levels of plasma free fatty acids or triglycerides (TGs) in a process called "lipotoxicity". Evidence from human studies and animal models suggests that lipid accumulation in the heart, skeletal muscle, pancreas, and liver play an important role in the pathogenesis of ...
Pablo, Perez-Martinez +2 more
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Excess lipid accumulation in nonadipose tissues may occur in the setting of high levels of plasma free fatty acids or triglycerides (TGs) in a process called "lipotoxicity". Evidence from human studies and animal models suggests that lipid accumulation in the heart, skeletal muscle, pancreas, and liver play an important role in the pathogenesis of ...
Pablo, Perez-Martinez +2 more
openaire +2 more sources
PUFAs dictate the balance of power in ferroptosis
Cell Calcium, 2023Ferroptosis is an iron-dependent form of cell death triggered by dysregulation of biochemical processes that culminate in lethal lipid peroxidation. Lipid metabolism is fundamental for determining ferroptotic fate, however, the mechanisms that alter lipid components to shape ferroptosis susceptibility remains elusive.
Shan Xin, Joel A Schick
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Omega-3-PUFA, Omega-6-PUFA and Mitochondria
2008Omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) belong to the essential fatty acids because the body cannot synthesize them and they must be obtained from the diet. That is why the role of the diet in prevention of mitochondrial damage and pathogenesis of hypertension, coronary artery disease, type 2 diabetes and atherosclerosis has been ...
Anna Gvozdjáková +4 more
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