Results 281 to 290 of about 183,516 (347)

Pulmonary Vascular Endothelial Dysfunction Is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model. [PDF]

Compr Physiol
Hyde J, Smith MA, Swami N, Hwang JH, Chao Y, Boehme J, Raff GW, Nilsson CN, Gong W, Deutsch GH, Johnson EG, Wang T, Black SM, Datar SA, Maltepe E, Fineman JR.   +15 more
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Mesenchymal stem cell therapy for pulmonary hypertension: an update. [PDF]

Front Bioeng Biotechnol
Tian R, Xu S, Liu C, Wang Y, Wu Y, Li L, Liu J.   +6 more
europepmc   +1 more source

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Endothelial cells in the pathogenesis of pulmonary arterial hypertension

European Respiratory Journal, 2021
Pulmonary arterial hypertension (PAH) is a devastating disease that involves pulmonary vasoconstriction, small vessel obliteration, large vessel thickening and obstruction, and development of plexiform lesions. PAH vasculopathy leads to progressive increases in pulmonary vascular resistance, right heart failure and, ultimately, premature death. Besides
Colin E. Evans, Nicholas D. Cober, Zhiyu Dai, Duncan J. Stewart, You-Yang Zhao   +4 more
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Endothelial Progenitor Cells in Pulmonary Arterial Hypertension

Trends in Cardiovascular Medicine, 2010
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by ongoing endothelial dysfunction and vascular remodeling. Endothelial progenitor cells (EPCs), mobilized from the bone marrow and resident locally in the lung, are thought to be important in maintaining vascular homeostasis; and there is growing interest in the potential ...
Gerhard-Paul, Diller, Thomas, Thum, Martin R, Wilkins, John, Wharton   +3 more
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Endothelial Progenitor Cells and Pulmonary Arterial Hypertension

Heart, Lung and Circulation, 2014
Pulmonary arterial hypertension (PAH) is a progressive disease characterised by lung endothelial cell dysfunction and vascular remodelling. A number of studies now suggest that endothelial progenitor cells (EPCs) may induce neovascularisation and could be a promising approach for cell based therapy for PAH.
Chen, H, Strappe, P, Chen, S, Wang, LX
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Isolation and Culture of Pulmonary Artery Endothelial Cells

Tissue and Cell, 1978
It has become increasingly evident that endothelial cells function as far more than a mechanical barrier between blood and parenchyma. Endothelial cells from one vesicular bed are known to differ structurally from those of another, and it has been suggested that they may differ functionally.
U S, Ryan, E, Clements, D, Habliston, J W, Ryan   +3 more
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Expression of 5-lipoxygenase in pulmonary artery endothelial cells

Biochemical Journal, 2002
Increased expression of 5-lipoxygenase (5LO) in pulmonary artery endothelial cells (PAECs) has been observed in disease states such as pulmonary hypertension and allergen challenge. To understand the function of endothelial 5LO, we examined the expression of this enzyme in normally cultured human PAECs and its characteristics when overexpressed.
Ying-Yi, Zhang, Jennifer L, Walker, Annong, Huang, John F, Keaney, Clary B, Clish, Charles N, Serhan, Joseph, Loscalzo   +6 more
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Pulmonary Artery Endothelial Cell Function in Swine Pseudomonas Sepsis

Journal of Surgical Research, 1996
A substantial increase in pulmonary vascular resistance is associated with sepsis and its sequelae (sepsis syndrome and septic shock). It is postulated that increased resistance may result from sepsis-induced endothelial cell injury or altered vasoreactivity secondary to pulmonary hypertension.
M, Kadletz, R J, Dignan, P G, Mullen, A C, Windsor, H J, Sugerman, A S, Wechsler   +5 more
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Effects of biaxial deformation on pulmonary artery endothelial cells

Journal of Cellular Physiology, 1989
AbstractAn apparatus has been designed to subject vascular cells grown on a compliant substrate in vitro to uniform, quantifiable levels of biaxial deformation. The system described can be controlled with respect to strain level, rate, and frequency to mimic the pulsatile force to which vascular cells are exposed in vivo under both physiologic and ...
S F, Gorfien, F K, Winston, L E, Thibault, E J, Macarak   +3 more
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Collagen synthesis by cloned pulmonary artery endothelial cells

Journal of Cellular Physiology, 1984
AbstractPulmonary artery endothelial cells were isolated from bovine fetal blood vessels and used for biosynthetic studies. At confluence, cultures were incubated in minimal essential medium (MEM) without serum containing [U‐14C]proline. After 24 hours, medium was removed and labeled proteins were precipitated by the addition of ammonium sulfate and ...
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