Results 1 to 10 of about 392,070 (180)

Validity of the ESC Risk Assessment in Idiopathic Pulmonary Arterial Hypertension in China

Frontiers in Cardiovascular Medicine, 2021
Background: The 2015 European pulmonary hypertension (PH) guidelines recommend a risk stratification strategy for pulmonary arterial hypertension (PAH).
Su-Gang Gong, Wen-Hui Wu, Chao Li, Qin-Hua Zhao, Rong Jiang, Ci-Jun Luo, Hong-Ling Qiu, Jin-Ming Liu, Lan Wang, Rui Zhang   +9 more
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Balloon pulmonary angioplasty combined with riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (PRACTICE study): study protocol for a randomized controlled trial

Trials, 2021
Background Management of inoperable chronic thromboembolic pulmonary hypertension (CTEPH) remains a clinical challenge. Currently, riociguat, a soluble guanylate-cyclase stimulator is recommended by international guidelines.
Qin-Hua Zhao, Su-Gang Gong, Jing He, Ping Yuan, Wen-Hui Wu, Ci-Jun Luo, Rong Jiang, Rui Zhang, Hong-Ling Qiu, Hui-Ting Li, Yuan Li, Jin-Ming Liu, Lan Wang   +12 more
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Comparative Effectiveness of Exercise Training for Patients With Chronic Thromboembolic Pulmonary Hypertension After Pulmonary Endarterectomy: A Systematic Review and Meta-Analysis

Frontiers in Cardiovascular Medicine, 2021
Background: Patients with chronic thromboembolic pulmonary hypertension (CTEPH) still experience reduced exercise capacity despite pulmonary endarterectomy (PEA). Exercise training improves the exercise capacity and quality of life (QoL) in patients with
Ya-Lin Zhao, Ping Yuan, Qin-Hua Zhao, Su-Gang Gong, Rui Zhang, Jing He, Ci-Jun Luo, Hong-Ling Qiu, Jin-Ming Liu, Lan Wang, Rong Jiang   +10 more
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Peak oxygen uptake is a strong prognostic predictor for pulmonary hypertension due to left heart disease

BMC Cardiovascular Disorders, 2022
Background Pulmonary hypertension in left heart disease (PH-LHD), which includes combined post- and precapillary PH (Cpc-PH) and isolated postcapillary PH (Ipc-PH), differs significantly in prognosis.
Xiu-Jun Zhong, Rong Jiang, Lu Yang, Ping Yuan, Su-Gang Gong, Qin-Hua Zhao, Ci-Jun Luo, Hong-Ling Qiu, Hui-Ting Li, Rui Zhang, Jing He, Lan Wang, Jie Tang, Jin-Ming Liu   +13 more
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CircGSAP alleviates pulmonary microvascular endothelial cells dysfunction in pulmonary hypertension via regulating miR-27a-3p/BMPR2 axis

Respiratory Research, 2022
Background Our previous study showed that circular RNA-gamma-secretase-activating protein (circGSAP) was down-regulated in pulmonary microvascular endothelial cells (PMECs) in response to hypoxia, and regulated the cell cycle of PMECs via miR-942-5p ...
Yuanyuan Sun, Rong Jiang, Xiaoyi Hu, Sugang Gong, Lan Wang, Wenhui Wu, Jinling Li, Xinyang Kang, Shijin Xia, Jinming Liu, Qinhua Zhao, Ping Yuan   +11 more
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Efficacy and safety of switching from bosentan or ambrisentan to macitentan in pulmonary arterial hypertension: A systematic review and meta-analysis

Frontiers in Cardiovascular Medicine, 2022
BackgroundThere is little evidence of the effectiveness of switching from the endothelin receptor antagonists (ERAs) bosentan and ambrisentan to a novel ERA, macitentan, in patients with pulmonary arterial hypertension (PAH).
Jie Li, Zu-Yuan Yang, Shang Wang, Ping Yuan, Qin-Hua Zhao, Su-Gang Gong, Hong-Ling Qiu, Ci-Jun Luo, Hui-Ting Li, Rui Zhang, Wen-Hui Wu, Jin-Ming Liu, Lan Wang, Shan-Shan Liu, Rong Jiang   +14 more
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Liver dysfunction in idiopathic pulmonary arterial hypertension: prevalence, characteristics and prognostic significance, a retrospective cohort study in China

BMJ Open, 2021
Objectives The aim was to elucidate the relationship between liver function and idiopathic pulmonary arterial hypertension (IPAH).Design and setting Retrospective, longitudinal study in urban tertiary care centre in Shanghai, China.Participants 407 IPAH ...
Rui Zhang, Jing He, Lan Wang, Ping Yuan, Wenhui Wu, Sugang Gong, Qinhua Zhao, Jinming Liu, Rong Jiang, Cijun Luo, Changwei Wu, Hongling Qiu, Jinling Li   +12 more
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Role of miR‐21‐5p/FilGAP axis in estradiol alleviating the progression of monocrotaline‐induced pulmonary hypertension

Animal Models and Experimental Medicine, 2022
Background Aberrant expression of microRNAs (miRNAs) has been associated with the pathogenesis of pulmonary hypertension (PH). It is, however, not clear whether miRNAs are involved in estrogen rescue of PH. Methods Fresh plasma samples were prepared from
Xiaoyi Hu, Qian Wang, Hui Zhao, Wenhui Wu, Qinhua Zhao, Rong Jiang, Jinming Liu, Lan Wang, Ping Yuan   +8 more
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Echocardiographic Prognosis Relevance of Attenuated Right Heart Remodeling in Idiopathic Pulmonary Arterial Hypertension

Frontiers in Cardiovascular Medicine, 2021
Background: Right ventricular (RV) function is a great determination of the fate in patients with pulmonary arterial hypertension (PAH). Monitoring RV structure back to normal or improvement should be useful for evaluation of RV function.
Qin-Hua Zhao, Su-Gang Gong, Rong Jiang, Chao Li, Ge-Fei Chen, Ci-Jun Luo, Hong-Ling Qiu, Jin-Ming Liu, Lan Wang, Lan Wang, Rui Zhang, Rui Zhang   +11 more
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Exosomal circular RNAs: Biogenesis, effect, and application in cardiovascular diseases

Frontiers in Cell and Developmental Biology, 2022
As natural nanoparticles, exosomes regulate a wide range of biological processes via modulation of its components, including circular RNAs (circRNAs).
Xiaoyi Hu, Hongran Qin, Yi Yan, Wenhui Wu, Sugang Gong, Lan Wang, Rong Jiang, Qinhua Zhao, Yuanyuan Sun, Qian Wang, Qian Wang, Shang Wang, Hui Zhao, Hui Zhao, Jinming Liu, Ping Yuan   +15 more
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