Results 101 to 110 of about 117,017 (302)

Mechanopharmacology of cellular microenvironment stiffness: Therapeutic strategies for age‐related diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Ageing brings about various biochemical, structural and mechanical alterations within tissues, profoundly impacting cellular behaviour and function. One of the hallmark changes observed with ageing is an increase in cellular microenvironment stiffness, a biomechanical property influenced by intrinsic factors within the cell and extrinsic factors from ...
Wang HaiYang   +3 more
wiley   +1 more source

Spontaneous Lung Herniation Leading to Extensive Subcutaneous Emphysema, Pneumothorax, Pneumomediastinum, and Pneumopericardium. [PDF]

open access: yes, 2018
Spontaneous lung herniation is a rare phenomenon in which the lung parenchyma along with the pleural membranes protrudes outside their usual boundaries and can lead to a wide variety of complications.
Ghani, Ali R.   +4 more
core   +1 more source

The impact of emphysema in pulmonary fibrosis [PDF]

open access: yesEuropean Respiratory Review, 2013
Several groups have described a syndrome in which idiopathic pulmonary fibrosis (IPF) coexists with pulmonary emphysema. This comes as no surprise since both diseases are associated with a history of exposure to cigarette smoke. The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is characterised by upper lobe emphysema and lower lobe ...
openaire   +5 more sources

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

open access: yesCell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu   +5 more
wiley   +1 more source

Knowledge and Concerns About Smoking‐Related Health Risks: A Cross‐Sectional Analysis of the 2021 International Tobacco Control Japan and Korea Surveys

open access: yesDrug and Alcohol Review, EarlyView.
ABSTRACT Introduction This cross‐sectional study examined: (i) knowledge of smoking‐related health risks among adults who currently and formerly smoke; (ii) concerns about personal health damage from smoking among adults who currently smoke; (iii) sociodemographic predictors of knowledge; and (iv) associations between knowledge and concerns in Japan ...
Tianze Sun   +20 more
wiley   +1 more source

Predicting clinical outcome with phenotypic clusters using quantitative CT fibrosis and emphysema features in patients with idiopathic pulmonary fibrosis.

open access: yesPLoS ONE, 2019
BackgroundThe clinical course of IPF varies. This study sought to identify phenotyping with quantitative computed tomography (CT) fibrosis and emphysema features using a cluster analysis and to assess prognostic impact among identified clusters in ...
So Hyeon Bak   +6 more
doaj   +1 more source

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

open access: yesEquine Veterinary Education, EarlyView.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald   +3 more
wiley   +1 more source

Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases

open access: yesJournal of Pharmacological Sciences, 2019
Pulmonary emphysema, inflammation and senescence-like phenotype are pathophysiological characteristics of chronic obstructive pulmonary disease (COPD).
Ryunosuke Nakashima   +12 more
doaj   +1 more source

STUDIES OF PULMONARY HYPERTENSION I. PULMONARY CIRCULATORY DYNAMICS IN PATIENTS WITH PULMONARY EMPHYSEMA AT REST 1 [PDF]

open access: bronze, 1953
Paul N. Yu   +6 more
openalex   +1 more source

Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]

open access: yes, 2007
Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit   +6 more
core   +1 more source

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