Results 111 to 120 of about 113,232 (234)

Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases

Journal of Pharmacological Sciences, 2019
Pulmonary emphysema, inflammation and senescence-like phenotype are pathophysiological characteristics of chronic obstructive pulmonary disease (COPD).
Ryunosuke Nakashima, Shunsuke Kamei, Hirofumi Nohara, Haruka Fujikawa, Kasumi Maruta, Taisei Kawakami, Yuka Eto, Noriki Takahashi, Mary Ann Suico, Toru Takeo, Naomi Nakagata, Hirofumi Kai, Tsuyoshi Shuto   +12 more
doaj   +1 more source

Exercise‐induced dynamic hyperinflation in chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease caused by inhalation of noxious particles, most commonly cigarette smoking. The consequent changes in airways, lung parenchyma and pulmonary vasculature lead to increased resistive, elastic and threshold loads and impaired capacity of the respiratory muscle pump. COPD
Rebecca F. D'Cruz, Dominic Wilkins, Caroline J. Jolley   +2 more
wiley   +1 more source

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

Experimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr, Philip N. Ainslie, Trevor Day   +2 more
wiley   +1 more source

Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi, David Wang, William W. Stringer, Richard Casaburi, Harry B. Rossiter   +4 more
wiley   +1 more source

Desmosine as a biomarker for the emergent properties of pulmonary emphysema. [PDF]

Front Med (Lausanne), 2023
Cantor J.
europepmc   +1 more source

Restoring Functional Status: A Long-Term Case Report of Severe Lung and Ventilatory Muscle Pump Dysfunction Involving Recurrent Bacterial Pneumonias [PDF]

, 2012
Background and Purpose: Prolonged mechanical ventilation contributes to immobility and deconditioning making efforts to safely discontinue ventilator support desirable. This case report documents how implementing physical therapy treatment interventions,
Laatsch-Lybeck, Linda Jean, Lipchik, Randolph J, Sobush, Dennis   +2 more
core   +2 more sources

Influence of low‐dose dopamine on exercise in fibrosing interstitial lung disease

Experimental Physiology, EarlyView.
ABSTRACT Fibrotic interstitial lung disease (FILD) is associated with dyspnoea and exercise intolerance. In other cardiorespiratory conditions, heightened carotid body (CB) chemoreflex sensitivity is associated with reduced exercise capacity. We tested the hypothesis that CB chemoreflex inhibition would improve exercise endurance time (EET) and reduce ...
Charlotte Chen, Jui‐Lin Fan, Michael Plunkett, Thalia Babbage, John Kolbe, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

Whole Genome Sequence Analysis of Weight Loss in 16 972 Participants With COPD Reveals Novel Risk Loci in DRAIC and RFX3

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Chronic obstructive pulmonary disease (COPD) is associated with musculoskeletal comorbidities, including cachexia. Weight loss (WL) is the major criterion for cachexia and increases risk for mortality in COPD. Risk factors for WL in COPD are incompletely understood.
Joe W. Chiles III, Alison Rocco, Vinodh Srinivasasainagendra, Harry B. Rossiter, Richard Casaburi, Anna Thalacker‐Mercer, J. Michael Wells, Emily S. Wan, Edwin K. Silverman, Michael H. Cho, Craig P. Hersh, Bruce M. Psaty, Sina A. Gharib, Yan Gao, George T. O'Connor, Leslie A. Lange, Stephen S. Rich, Ani W. Manichaikul, R. Graham Barr, Victor E. Ortega, Deborah A. Meyers, Albert V. Smith, Hemant K. Tiwari, Merry‐Lynn N. McDonald   +23 more
wiley   +1 more source

Pulmonary Emphysema [PDF]

BMJ, 1982
openaire   +2 more sources

Non‐Communicable Disease, Metabolic and Lifestyle Risk Factor Profiles in South African University Students: A Latent Class Analysis

Public Health Challenges, Volume 5, Issue 2, June 2026.
The NCD prevalence and overall risk profile of South African university students are understudied, despite widespread unhealthy lifestyles. Chronic respiratory diseases, CMDs and lifestyle risk factors are common. Findings support targeted interventions addressing stress‐related factors and substance use, alongside population‐level strategies to ...
Melissa Janse van Vuren, Wayne Derman, Jason Bantjes, Innocent Maposa, Liske Kotze‐Horstmann   +4 more
wiley   +1 more source