Results 71 to 80 of about 1,195,100 (331)

Critical role of tumor necrosis factor receptor 1 in the pathogenesis of pulmonary emphysema in mice

International Journal of COPD, 2016
Masaki Fujita,1 Hiroshi Ouchi,2 Satoshi Ikegame,2 Eiji Harada,2 Takemasa Matsumoto,1 Junji Uchino,1 Yoichi Nakanishi,2 Kentaro Watanabe1 1Department of Respiratory Medicine, Faculty of Medicine, Fukuoka University, 2Research Institute for Diseases of ...
Fujita M, Ouchi H, Ikegame S, Harada E, Matsumoto T, Uchino J, Nakanishi Y, Watanabe K   +7 more
doaj  

Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD

Respiratory Research, 2019
Background The mechanisms underlying airflow obstruction in COPD cannot be distinguished by standard spirometry. We ascertain whether mathematical modeling of airway biomechanical properties, as assessed from spirometry, could provide estimates of ...
Mariaelena Occhipinti, Matteo Paoletti, Brian J. Bartholmai, Srinivasan Rajagopalan, Ronald A. Karwoski, Cosimo Nardi, Riccardo Inchingolo, Anna R. Larici, Gianna Camiciottoli, Federico Lavorini, Stefano Colagrande, Vito Brusasco, Massimo Pistolesi   +12 more
doaj   +1 more source

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases

Respiratory Research, 2016
BackgroundEmphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been ...
K. Ostridge, N. Williams, V. Kim, S. Harden, S. Bourne, N. Coombs, P. Elkington, Raúl San José Estépar, G. Washko, K. Staples, T. Wilkinson   +10 more
semanticscholar   +1 more source

Identification of Clinically Distinct Clusters in Patients With Severe COPD Using Circulating Blood Cell Population Parameters

Respirology, EarlyView.
This study investigated whether blood cell population data, in addition to cell counts, can identify clinically relevant COPD subgroups. Four distinct inflammatory profiles were identified with distinct clinical characteristics. Cell population data have the potential to provide additional insights beyond inflammatory cell counts and improve patient ...
Pauline J. M. Kuks, Jorine E. Hartman, Else A. M. D. ter Haar, L. Joost van Pelt, Dirk‐Jan Slebos, Maarten van den Berge, Simon D. Pouwels   +6 more
wiley   +1 more source

A case report of subconjunctival emphysema as a rare complication of pulmonary resections

Journal of Minimal Access Surgery
Lung volume reduction surgery (LVRS) is performed to the selected patients with lung emphysema who have higher residual volume, restricted pulmonary functions and limited diaphragmatic movement. Post-operative prolonged air leak is not uncommon following
Ismail Sarbay, Akif Turna
doaj   +1 more source

Severe pulmonary hypertension due to combined pulmonary fibrosis and emphysema: another cause of death among smokers

Autopsy and Case Reports, 2017
In 2005, the combined pulmonary fibrosis and emphysema (CPFE) was first defined as a distinct entity, which comprised centrilobular or paraseptal emphysema in the upper pulmonary lobes, and fibrosis in the lower lobes accompanied by reduced diffused ...
André Carramenha de Góes Hirano, Eduardo Pelegrineti Targueta, Fernando Peixoto Ferraz de Campos, João Augusto dos Santos Martines, Dafne Andrade, Silvana Maria Lovisolo, Aloisio Felipe-Silva   +6 more
doaj   +1 more source

A Novel Method Using Dual‐Energy Computed Tomography for Detecting Amiodarone‐Induced Lung Injury: A Cohort Pilot Study

Respirology, EarlyView.
There is no gold standard for detecting amiodarone‐induced‐lung injury (AILD). Dual‐Energy‐Computed‐Tomography (DECT) depicts iodine deposition in lungs abnormalities and the liver. We found a substantial correlation between the DECT assessment of AILD and comprehensive clinical evaluation of AILD. DECT can assist in the diagnosis of AILD.
Naama R. Bogot, Ariel Rokach, Irith Hadas‐Halperen, Yehonatan Cohen, Ayal Romem, Moshe Rav‐Acha, Tal Hasin, Gabriel Izbicki, Nissim Arish   +8 more
wiley   +1 more source

Combined pulmonary fibrosis and emphysema: a narrative review

Frontiers in Medicine
Combined pulmonary fibrosis and emphysema (CPFE) is defined as a clinical-radiological-physiological syndrome characterized by upper-lobe emphysema and fibrosis predominantly in the lower lobes.
Wenjing Zeng, Binmiao Liang, Xuemei Ou
doaj   +1 more source

Surgical Outcomes of Lung Cancer Patients with Combined Pulmonary Fibrosis and Emphysema and Those with Idiopathic Pulmonary Fibrosis without Emphysema.

Annals of Thoracic and Cardiovascular Surgery, 2016
OBJECTIVES Combined pulmonary fibrosis and emphysema (CPFE) is a unique disorder. The aim of this study was to compare the surgical outcomes of lung cancer patients with CPFE and those with idiopathic pulmonary fibrosis (IPF) without emphysema ...
Seijiro Sato, T. Koike, T. Hashimoto, H. Ishikawa, A. Okada, Takehiro Watanabe, M. Tsuchida   +6 more
semanticscholar   +1 more source