Results 71 to 80 of about 64,581 (287)
The FEBS Journal, EarlyView.A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz +6 more
wiley +1 more source
The impact of emphysema in pulmonary fibrosis [PDF]
European Respiratory Review, 2013 Several groups have described a syndrome in which idiopathic pulmonary fibrosis (IPF) coexists with pulmonary emphysema. This comes as no surprise since both diseases are associated with a history of exposure to cigarette smoke. The syndrome of combined pulmonary fibrosis and emphysema (CPFE) is characterised by upper lobe emphysema and lower lobe ...
openaire +5 more sources
Impact of N‐linked glycans on the dual short fibulin/LTBP‐4 axes regulating elastogenesis
The FEBS Journal, EarlyView.Elastic fiber assembly is orchestrated by multiple glycoproteins. We delineate the molecular basis of two key axes involved in elastic fiber formation—LTBP‐4L/fibulin‐4 and LTBP‐4S/fibulin‐5. We show that N‐linked glycans on these glycoproteins regulate their interactions and conformations, both of which are critical aspects in elastic fiber formation.
Valentin Nelea +8 more
wiley +1 more source
Turning the tide on bronchiectasis in adult Aboriginal Australians: from neglect to action
Internal Medicine Journal, EarlyView.Abstract Chronic respiratory disorders are highly prevalent among adult Aboriginal and Torres Strait Islander peoples, with emerging evidence suggesting that there is a significant burden of bronchiectasis contributing to overall higher morbidity and mortality.
Subash S. Heraganahally +8 more
wiley +1 more source
PLoS ONE, 2019 BackgroundThe clinical course of IPF varies. This study sought to identify phenotyping with quantitative computed tomography (CT) fibrosis and emphysema features using a cluster analysis and to assess prognostic impact among identified clusters in ...
So Hyeon Bak +6 more
doaj +1 more source
Stem Cell Research & Therapy, 2019 Introduction Pulmonary emphysema is a major component of chronic obstructive pulmonary disease (COPD). Emphysema progression attributed not only to alveolar structure loss and pulmonary regeneration impairment, but also to excessive inflammatory response,
Ying-Wei Lan +7 more
doaj +1 more source
Journal of Diabetes Investigation, EarlyView.This systematic review and meta‐analysis evaluates the impact of SGLT‐2 inhibitors on COPD exacerbations in patients with Type 2 diabetes mellitus (T2DM). Our findings demonstrate that SGLT‐2 inhibitors significantly reduce the frequency of COPD exacerbations by 35% compared to other antidiabetic agents, offering dual benefits in glycemic control and ...
Muhammed Shabil +14 more
wiley +1 more source
STUDIES OF PULMONARY HYPERTENSION I. PULMONARY CIRCULATORY DYNAMICS IN PATIENTS WITH PULMONARY EMPHYSEMA AT REST 1 [PDF]
, 1953 Paul N. Yu +6 more
openalex +1 more source
Journal of the European Academy of Dermatology and Venereology, EarlyView.This cohort study of 1793 atopic dermatitis patients (aged ≥ 12) found higher infection rates with Janus kinase inhibitor treatment compared to biologic treatment, particularly for herpes infections, with a history of viral or fungal skin infection as a risk factor associated with infection.
Lian F. van der Gang +22 more
wiley +1 more source