Results 31 to 40 of about 581,169 (264)

Oral antibiotics relieve allergic asthma in post-weaning mice via reducing iNKT cells and function of ADRB2

Frontiers in Immunology, 2022
The role of normal gut microbiota in asthma or ovalbumin (OVA)-induced asthma tolerance (OT) remains unclear. Here, we established mouse models of asthma and OT followed by 2 weeks of antibiotic treatment, to clear the gut microbiota.
Na Li, Na Li, Jie Chen, Sitao Xie, Meng Zhang, Tianyun Shi, Yanchao He, Zhijun Jie, Xiao Su   +8 more
doaj   +1 more source

Vagal α7nAChR signaling regulates α7nAChR+Sca1+ cells during lung injury repair

Stem Cell Research & Therapy, 2020
Background The distal airways of the lung and bone marrow are innervated by the vagus nerve. Vagal α7nAChR signaling plays a key role in regulating lung infection and inflammation; however, whether this pathway regulates α7nAChR+Sca1+ cells during lung ...
Xiaoyan Chen, Jie Chen, Yuanlin Song, Xiao Su   +3 more
doaj   +1 more source

Non-invasive detection of severe PH in lung disease using magnetic resonance imaging

Frontiers in Cardiovascular Medicine, 2023
IntroductionSevere pulmonary hypertension (mean pulmonary artery pressure ≥35 mmHg) in chronic lung disease (PH-CLD) is associated with high mortality and morbidity.
Dheyaa Alkhanfar, Dheyaa Alkhanfar, Dheyaa Alkhanfar, Krit Dwivedi, Faisal Alandejani, Yousef Shahin, Yousef Shahin, Samer Alabed, Samer Alabed, Chris Johns, Pankaj Garg, A. A. Roger Thompson, A. A. Roger Thompson, Alexander M. K. Rothman, Alexander M. K. Rothman, Abdul Hameed, Athanasios Charalampopoulos, Jim M. Wild, Jim M. Wild, Robin Condliffe, David G. Kiely, David G. Kiely, Andrew J. Swift, Andrew J. Swift   +23 more
doaj   +1 more source

CMR Measures of Left Atrial Volume Index and Right Ventricular Function Have Prognostic Value in Chronic Thromboembolic Pulmonary Hypertension

Frontiers in Medicine, 2022
Providing prognostic information is important when counseling patients and planning treatment strategies in chronic thromboembolic pulmonary hypertension (CTEPH).
Yousef Shahin, Yousef Shahin, Samer Alabed, Samer Alabed, Syed Rehan Quadery, Robert A. Lewis, Christopher Johns, Dheyaa Alkhanfar, Maria Sukhanenko, Faisal Alandejani, Pankaj Garg, Charlie A. Elliot, Abdul Hameed, Abdul Hameed, Athaniosis Charalampopoulos, James M. Wild, James M. Wild, Robin Condliffe, Andrew J. Swift, Andrew J. Swift, Andrew J. Swift, David G. Kiely, David G. Kiely, David G. Kiely   +23 more
doaj   +1 more source

Modifications of Pseudomonas aeruginosa cell envelope in the cystic fibrosis airway alters interactions with immune cells

Scientific Reports, 2017
Pseudomonas aeruginosa is a ubiquitous environmental organism and an opportunistic pathogen that causes chronic lung infections in the airways of cystic fibrosis (CF) patients as well as other immune-compromised individuals.
Preston J. Hill, Julia M. Scordo, Jesús Arcos, Stephen E. Kirkby, Mark D. Wewers, Daniel J. Wozniak, Jordi B. Torrelles   +6 more
doaj   +1 more source

Crosstalks between inflammasome and autophagy in cancer

Journal of Hematology & Oncology, 2020
Both inflammasomes and autophagy have important roles in the intracellular homeostasis, inflammation, and pathology; the dysregulation of these processes is often associated with the pathogenesis of numerous cancers.
Chaeuk Chung, Wonhyoung Seo, Prashanta Silwal, Eun-Kyeong Jo   +3 more
doaj   +1 more source

Clinical significance of changes in serum inflammatory factors in patients with chronic obstructive pulmonary disease and pulmonary infection

Journal of International Medical Research, 2021
Background Chronic obstructive pulmonary disease (COPD) is often accompanied by pulmonary infection, inflammatory responses, decreased immunity, and decreased lung function.
Jun Zhou, Feng Jin, Feng Wu
doaj   +1 more source

Pulmonary complications of HIV infection [PDF]

Respirology, 2007
The lung is a frequent site of opportunistic infection in patients with HIV infection, and noninfectious pulmonary disorders associated with HIV infection and antiretroviral treatments are increasingly common. The severity of immunocompromise, with CD4+ lymphocyte count the most reliable surrogate, is the primary determinant of the risk of developing ...
openaire   +3 more sources

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Alveolar cell composition in interstitial lung disease and the development of a pulmonary progressive fibrosing phenotype: a retrospective cohort study

Respiratory Research
Background Immunological bronchoalveolar lavage (iBAL) is a frequently employed diagnostic tool in interstitial lung disease (ILD). The association between iBAL cellular composition and disease progression remains elusive.
Iris A. Simons, Bart G. Boerrigter, Maud C.M. Hovestadt, Kirsten A. Mooij-Kalverda, Shiqi Zhang, Leonoor S. Boers, Anke H. Maitland– van der Zee, Esther J. Nossent, Jan Willem Duitman   +8 more
doaj   +1 more source