Results 31 to 40 of about 2,650,471 (308)

The beta2 integrin CD11c distinguishes a subset of cytotoxic pulmonary T cells with potent antiviral effects in vitro and in vivo [PDF]

, 2005
Background The integrin CD11c is known as a marker for dendritic cells and has recently been described on T cells following lymphotropic choriomeningitis virus infection, a systemic infection affecting a multitude of organs.
Nina Peters, Doths, Sandra, Peter JM Openshaw, Jürgen Schwarze, Openshaw, Peter J M, Wang, HW, Peters, N, Wang Hongwei, Koerner-Rettberg, C, Schwarze Jürgen, Beyer, Marc, Koerner-Rettberg, Cordula, Beyer Marc, Openshaw Peter JM, Marc Beyer, Koerner-Rettberg Cordula, Schwarze, J, Cordula Koerner-Rettberg, Doths, S, Peters Nina, Doths Sandra, Beyer, M, Hongwei Wang, Schwarze, Jürgen, Openshaw, PJ, Peters, Nina, Sandra Doths, Wang, Hongwei   +27 more
core   +2 more sources

Biomarkers and bacterial pneumonia risk in patients with treated HIV infection: a case-control study [PDF]

, 2013
Background: Despite advances in HIV treatment, bacterial pneumonia continues to cause considerable morbidity and mortality in patients with HIV infection. Studies of biomarker associations with bacterial pneumonia risk in treated HIV-infected patients do
Kunisaki, KM, Brian Angus, Gordin, Fred M., Sarah L Pett, Angus, Brian, Bjerk, Sonja M., Sonja M. Bjerk, Sean Emery, Kunisaki, Ken M, Neuhaus, Jacqueline, Ken M Kunisaki, Jacqueline Neuhaus, Ristola, M., Baker, Jason V., Gordin, FM, Pett, Sarah L, Jason V Baker, Pett, Sarah L., Neuhaus, J, Sonja M Bjerk, Stephan, C, Baker, Jason V, Fred M Gordin, Christoph Stephan, Gordin, Fred M, Bjerk, Sonja M, INSIGHT SMART Study Group, Kunisaki, Ken M., Fred M. Gordin, Stephan, Christoph, Casseb, Jorge Simão do Rosário, Bjerk, SM, Ken M. Kunisaki, Emery, S, Angus, B, Sarah L. Pett, Jason V. Baker, Emery, Sean, Baker, JV, Pett, SL   +39 more
core   +1 more source

Vagal α7nAChR signaling regulates α7nAChR+Sca1+ cells during lung injury repair

Stem Cell Research & Therapy, 2020
Background The distal airways of the lung and bone marrow are innervated by the vagus nerve. Vagal α7nAChR signaling plays a key role in regulating lung infection and inflammation; however, whether this pathway regulates α7nAChR+Sca1+ cells during lung ...
Xiaoyan Chen, Jie Chen, Yuanlin Song, Xiao Su   +3 more
doaj   +1 more source

Application of [18F]FLT‐PET in pulmonary arterial hypertension: a clinical study in pulmonary arterial hypertension patients and unaffected bone morphogenetic protein receptor type 2 mutation carriers [PDF]

, 2021
Pulmonary arterial hypertension is a heterogeneous group of diseases characterized by vascular cell proliferation leading to pulmonary vascular remodelling and ultimately right heart failure. Previous data indicated that 3′‐deoxy‐3′‐[18F]‐fluorothymidine
Onno A. Spruijt, Jansen, Samara MA, Anton V. Noordegraaf, Botros, Liza, Liza Botros, Ashek, Ali, de Man, Frances S, Bogaard, Harm J., Marc C. Huisman, Tramper, Jelco, Spruijt, Onno A., Harms, Hans, Jelco Tramper, Samara M.A. Jansen, Jansen, Samara M. A., Hans Harms, Anton Vonk Noordegraaf, Harm J. Bogaard, de Man, Frances S., Bogaard, Harm J, Zhao, Lan, Aman, Jurjan, Ali Ashek, Frances S. de Man, Frances S. deMan, Noordegraaf, Anton V., Spruijt, Onno A, Huisman, Marc C., Huisman, Marc C, Lan Zhao, Noordegraaf, Anton, Jurjan Aman   +31 more
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Modifications of Pseudomonas aeruginosa cell envelope in the cystic fibrosis airway alters interactions with immune cells

Scientific Reports, 2017
Pseudomonas aeruginosa is a ubiquitous environmental organism and an opportunistic pathogen that causes chronic lung infections in the airways of cystic fibrosis (CF) patients as well as other immune-compromised individuals.
Preston J. Hill, Julia M. Scordo, Jesús Arcos, Stephen E. Kirkby, Mark D. Wewers, Daniel J. Wozniak, Jordi B. Torrelles   +6 more
doaj   +1 more source

CMR Measures of Left Atrial Volume Index and Right Ventricular Function Have Prognostic Value in Chronic Thromboembolic Pulmonary Hypertension

Frontiers in Medicine, 2022
Providing prognostic information is important when counseling patients and planning treatment strategies in chronic thromboembolic pulmonary hypertension (CTEPH).
Yousef Shahin, Yousef Shahin, Samer Alabed, Samer Alabed, Syed Rehan Quadery, Robert A. Lewis, Christopher Johns, Dheyaa Alkhanfar, Maria Sukhanenko, Faisal Alandejani, Pankaj Garg, Charlie A. Elliot, Abdul Hameed, Abdul Hameed, Athaniosis Charalampopoulos, James M. Wild, James M. Wild, Robin Condliffe, Andrew J. Swift, Andrew J. Swift, Andrew J. Swift, David G. Kiely, David G. Kiely, David G. Kiely   +23 more
doaj   +1 more source

Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset [PDF]

, 2011
Acute periods of pulmonary exacerbation are the single most important cause of morbidity in cystic fibrosis patients, and may be associated with a loss of lung function.
Matt W Johnson, Rogers, Geraint B., Carroll, Mary P., Carroll, Mary P, Mayer-Hamblett, Nicole, Geraint B Rogers, Jürgen Schwarze, Kenneth D Bruce, Mary P Carroll, Johnson, Matt W, Hoffman, Lucas R, Nicole Mayer-Hamblett, Johnson, Matt W., Rogers, Geraint B, Schwarze, Juergen, Schwarze, Jürgen, Bruce, Kenneth D., Lucas R Hoffman, Hoffman, Lucas R., Bruce, Kenneth D   +19 more
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Characterization and 3-Year Survival of Clinical Subtypes and Host Response Phenotypes of Acute Respiratory Failure Requiring Mechanical VentilationTake-Home Points

CHEST Critical Care
Background: Acute respiratory failure (ARF) requiring invasive mechanical ventilation affects approximately 1.5 million adults in the United States annually.
Georgios D. Kitsios, MD, PhD, William G. Bain, MD, John W. Evankovich, MD, Niall Prendergast, MD, Matthew Hensley, MD, Tomeka Suber, MD, PhD, Kyle Inman, MD, Caitlin Schaefer, MPH, Melissa Saul, MS, Xiaoping Chen, MS, Menaal Haque, MPH, Janet Lee, MD, Alicia Rizzo, MD, PhD, Shulin Qin, MD, PhD, Yingze Zhang, PhD, Alison Morris, MD, Charles Dela Cruz, MD, PhD, Seyed Mehdi Nouraie, MD, PhD, Bryan J. McVerry, MD, Faraaz A. Shah, MD, MPH   +19 more
doaj   +1 more source

Clinical significance of changes in serum inflammatory factors in patients with chronic obstructive pulmonary disease and pulmonary infection

Journal of International Medical Research, 2021
Background Chronic obstructive pulmonary disease (COPD) is often accompanied by pulmonary infection, inflammatory responses, decreased immunity, and decreased lung function.
Jun Zhou, Feng Jin, Feng Wu
doaj   +1 more source

Non-invasive detection of severe PH in lung disease using magnetic resonance imaging

Frontiers in Cardiovascular Medicine, 2023
IntroductionSevere pulmonary hypertension (mean pulmonary artery pressure ≥35 mmHg) in chronic lung disease (PH-CLD) is associated with high mortality and morbidity.
Dheyaa Alkhanfar, Dheyaa Alkhanfar, Dheyaa Alkhanfar, Krit Dwivedi, Faisal Alandejani, Yousef Shahin, Yousef Shahin, Samer Alabed, Samer Alabed, Chris Johns, Pankaj Garg, A. A. Roger Thompson, A. A. Roger Thompson, Alexander M. K. Rothman, Alexander M. K. Rothman, Abdul Hameed, Athanasios Charalampopoulos, Jim M. Wild, Jim M. Wild, Robin Condliffe, David G. Kiely, David G. Kiely, Andrew J. Swift, Andrew J. Swift   +23 more
doaj   +1 more source