Results 171 to 180 of about 37,784 (244)

Sleep apnea in REM sleep as an amplifier of vascular contributions to Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Obstructive sleep apnea (OSA), a common though underdiagnosed disorder in older adults, represents a potential upstream vascular stressor linked to increased Alzheimer's disease (AD) risk. In this Perspective article, we propose a stage‐informed framework in which rapid eye movement (REM) sleep‐related respiratory events amplify vascular ...
Destiny E. Berisha, Ruth M. Benca, Bryce A. Mander   +2 more
wiley   +1 more source

Dynamic Urinary Albumin/Creatinine Ratio Patterns Predict Adverse Outcomes in HFpEF: TOPCAT Cohort Analysis

Clinical Cardiology, Volume 49, Issue 8, August 2026.
Among 746 HFpEF patients in TOPCAT, latent class modeling identified three uACR trajectories: stable, decreasing, and fluctuating high. The fluctuating high trajectory independently predicted the composite of cardiovascular death, aborted cardiac arrest, or heart failure hospitalization, and adding trajectory data modestly improved risk prediction ...
Weiping Xiao, Zhiyan Wang, Di‐en Yan, Min‐an Peng, Xinyuan Zhou   +4 more
wiley   +1 more source

Braking bad: do environmental hypoxia and contractile activity really work well together to support muscle angiogenesis?

The Journal of Physiology, EarlyView.
Emilie Roudier, Pierre Lemieux
wiley   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal, Anuradha Bankar, Vinicio A. de Jesus Perez   +2 more
wiley   +1 more source

The Immuno‐Cardiovascular Storm of Pre‐Eclampsia: Cytokine‐Mediated Endothelial Injury, Thrombosis, and Maternal Cardiovascular Instability

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Placental ischemia in pre‐eclampsia initiates cytokine‐driven endothelial dysfunction, angiogenic imbalance, oxidative stress, and thromboinflammation. Elevated TNF‐α, IL‐6, IL‐17, sFlt‐1, and complement activation promote vasoconstriction, thrombosis, and cardiovascular instability.
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Regulation of Microtubule Stability in Pulmonary Microvascular Endothelial Cells in Rats with Severe Acute Pancreatitis: Qingyi Decoction is a Potential CDK5 Inhibitor. [PDF]

J Inflamm Res
Cao Y, Li F, Sun Z, Liu J, Liu J, Yang Q, Ge P, Luo Y, Chen H.   +8 more
europepmc   +1 more source

Susceptibility of porcine pulmonary microvascular endothelial cells to porcine reproductive and respiratory syndrome virus. [PDF]

J Vet Med Sci, 2020
Li P, Yang Z, Ma S, Hu G, Dong H, Zhang T.   +5 more
europepmc   +1 more source

The Interstitial Fluid Compartment: Still Unrecognized or Biophysically Well Described?

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ABSTRACT The proposal of a “new third bodily system for circulation of fluid” has been recently put forward. The present article sheds light on all available physiological knowledge concerning exactly this same space, defined as “interstitial compartment” as originally hypothesized by Ernest Starling about 130 years ago. We provide here a brief updated
Daniela Negrini, Giuseppe Miserocchi
wiley   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

miR-642a-5p partially mediates the effects of lipopolysaccharide on human pulmonary microvascular endothelial cells via eEF2. [PDF]

FEBS Open Bio, 2020
Fei L, Sun G, You Q.
europepmc   +1 more source