Results 181 to 190 of about 37,784 (244)

Ginseng as a Functional Food Intervention for Interstitial Lung Disease: A Review of the Benefits and Molecular Mechanisms

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
From the perspectives of food science and nutrition, this article reviews the regulatory mechanisms through which ginseng and its major components influence ILD‐related pathological processes and discusses its potential as a functional food and future research directions. ABSTRACT Interstitial lung disease (ILD) encompasses a complex group of disorders
Jiahui Li   +7 more
wiley   +1 more source

Associations of C‐Reactive Protein‐Triglyceride Glucose Index and Estimated Pulse Wave Velocity With All‐Cause Mortality: A Nationwide Prospective Cohort Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims The combined prognostic value of metaflammation and vascular aging markers in cardiovascular‐kidney‐metabolic (CKM) syndrome is unclear. This study aimed to assess the independent and joint associations of the C‐reactive protein‐triglyceride glucose index (CTI) and estimated pulse wave velocity (ePWV) with all‐cause ...
Huixiao Yuan   +8 more
wiley   +1 more source

Bone Marrow Stem Cell Exosomes Protect Lung Cells from Oxygen Damage by Regulating miR‐23a‐3p/Slc7a2 Pathway

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 8, August 2026.
Exosomal miR‐23a‐3p from BMSCs directly targets Slc7a2 mRNA. By repressing Slc7a2, miR‐23a‐3p suppresses hyperoxia‐triggered apoptosis, facilitates proliferation and reduces ROS production in AECIIs in vitro. The miR‐23a‐3p/Slc7a2 axis modulates numerous biochemical markers in AECII supernatant and neonatal rat serum under hyperoxia (P 〈 0.05 ...
Qifei He   +3 more
wiley   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 8, August 2026.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang   +9 more
wiley   +1 more source

The Role of Aging on Pulmonary Microvascular Endothelial Cell Barrier Function

open access: yes
Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterized by widespread injury and inflammation within the lungs. Mortality due to ARDS is high, especially in the elderly population, and there are no effective therapeutics available.
openaire   +1 more source

Coronary Microvascular Dysfunction: Epidemiology, Pathophysiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This visual summary illustrates the key aspects of coronary microvascular dysfunction (CMD) in angina with nonobstructive coronary artery disease (NOCAD), including epidemiology, pathophysiology (microvascular remodeling and endothelial dysfunction), the protective NRG‐1/ErbB signaling pathway, diagnostic methods, and both Western and traditional ...
Zhao Ge   +8 more
wiley   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy   +8 more
wiley   +1 more source

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