Results 11 to 20 of about 75,851 (198)
Alveolar lipids in pulmonary disease. A review
Lipids in Health and Disease, 2020 Lung lipid metabolism participates both in infant and adult pulmonary disease. The lung is composed by multiple cell types with specialized functions and coordinately acting to meet specific physiologic requirements. The alveoli are the niche of the most
Christina W. Agudelo +2 more
doaj +1 more source
PLoS ONE, 2020 Smoke exposure is known to decrease total pulmonary surfactant and alter its composition, but the role of surfactant in chronic obstructive pulmonary disease (COPD) remains unknown. We aimed to analyze the compositional changes in the surfactant lipidome
Christina W Agudelo +8 more
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The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels [PDF]
, 2013 Aim: Topical administration of siRNA nanocarriers is a promising approach in the treatment of pulmonary disorders. Pulmonary surfactant, covering the entire alveolar surface of mammalian lungs, will be one of the first interfaces that siRNA nanocarriers ...
Braeckmans, Kevin +4 more
core +1 more source
The role of surface charge in the interaction of nanoparticles with model pulmonary surfactants [PDF]
, 2018 Inhaled nanoparticles traveling through the airways are able to reach the respiratory zone of the lungs. In such event, the incoming particles first enter in contact with the liquid lining the alveolar epithelium, the pulmonary surfactant.
Berret, J. -F., Mousseau, F.
core +4 more sources
Molecules, 2023 During the COVID-19 pandemic, the treatment of pulmonary fungal infection faced noteworthy challenges. Amphotericin B has shown promising therapeutic effects as an inhalation treatment for pulmonary fungal infections, especially those associated with the
Juan Wang +3 more
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New therapy by surfactant to avoid neuro/psychiatric problems caused by cerebral hypoxia
European Psychiatry, 2021 Introduction Covid-19 causes neuro/psychiatric problems by cerebral hypoxia. Objectives My therapy could allow us to cross Covid-19 infection by minimizing both immediate and chronic lung damage and would avoid many deaths and neuro/psychiatric ...
L. Bracco
doaj +1 more source
Surfactant function in neonates with respiratory distress syndrome [PDF]
, 1998 The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was ...
Griese, Matthias, Westerburg, Bettina
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Journal of Applied Physiology, 1982 Pulmonary surfactant reduces the surface tension of the alveolar air-liquid interface, thereby providing mechanical stability and preventing alveolar atelectasis. More than 50% of surfactant is dipalmitoyl phosphatidylcholine, a material that is capable of reducing the surface tension of the alveolar interface to uniquely low values.
P, Gutkowski, W, Lejman
openaire +4 more sources
Pediatrics and Neonatology, 2010 Chronic lung disease continues to be a major complication in premature infants with severe respiratory distress syndrome (RDS). This is despite having advanced ventilatory care, prenatal corticosteroids, and postnatal surfactant therapies.
Chia-Feng Yang +5 more
doaj +1 more source
Interfacial Reactions of Ozone with Surfactant Protein B in a Model Lung Surfactant System [PDF]
, 2010 Oxidative stresses from irritants such as hydrogen peroxide and ozone (O_3) can cause dysfunction of the pulmonary surfactant (PS) layer in the human lung, resulting in chronic diseases of the respiratory tract.
Beauchamp, J. L. +9 more
core +2 more sources