Results 11 to 20 of about 1,349,045 (346)

The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels. [PDF]

Nanomedicine, 2013
Aim: Topical administration of siRNA nanocarriers is a promising approach in the treatment of pulmonary disorders. Pulmonary surfactant, covering the entire alveolar surface of mammalian lungs, will be one of the first interfaces that siRNA nanocarriers ...
Lynn De Backer, K. Braeckmans, J. Demeester, S. D. De Smedt, K. Raemdonck   +4 more
semanticscholar   +3 more sources

A recipe for a good clinical pulmonary surfactant

Biomedical Journal, 2022
The lives of thousands premature babies have been saved along the last thirty years thanks to the establishment and consolidation of pulmonary surfactant replacement therapies (SRT).
Jesús Pérez-Gil
doaj   +1 more source

Circulação extracorpórea por membrana (ECMO) em recém-nascido com insuficiência respiratória por síndrome de aspiração meconial: efeitos da administração de surfactante exógeno Extracorporeal membrane oxygenation (ECMO) in a neonate with respiratory distress due to meconium aspiration syndrome: Effect of the administration of exogenous surfactant

Jornal de Pediatria, 2001
OBJETIVO: apresentar a evolução clínica de recém-nascido portador de insuficiência respiratória grave neonatal secundária à Sindrome de Aspiração Meconial tratado por Circulação Extracorpórea por Membrana, ou, conforme o termo consagrado em língua ...
João Gilberto Maksoud-Filho, Edna Maria Albuquerque Diniz, Maria Esther J. Ceccon, Ana Lúcia S. Galvani, Maria D'Andrea A. B. Chamelian, Maria Lúcia de Pinho, Flávio Adolfo C. Vaz   +6 more
doaj   +1 more source

Xylem surfactants introduce a new element to the cohesion-tension theory [PDF]

, 2016
Vascular plants transport water under negative pressure without constantly creating gas bubbles that would disable their hydraulic systems. Attempts to replicate this feat in artificial systems almost invariably result in bubble formation, except under ...
Do, Aissa YT, Espino, Susana, Jansen, Steven, Michaud, Joseph M, Nima, Neda, Papahadjopoulos-Sternberg, Brigitte, Romo, David M, Schenk, H Jochen, Steppe, Kathy, Yang, Jinlong, Zuo, Yi Y   +10 more
core   +1 more source

Insights Gained Into the Treatment of COVID19 by Pulmonary Surfactant and Its Components

Frontiers in Immunology, 2022
Pulmonary surfactant constitutes an important barrier that pathogens must cross to gain access to the rest of the organism via the respiratory surface.
Dan Li, Dan Li, Xianzheng Wang, Yingzhao Liao, Shouchuan Wang, Jinjun Shan, Jianjian Ji   +6 more
doaj   +1 more source

Effects of Exogenous Surfactants on the Parameters of Blood Gas Composition in Neonatal Respiratory Distress Syndrome

Общая реаниматология, 2007
Objective: to study the effects of the surfactants Surfactant-BL and Curosurf on pulmonary oxygenizing properties in preterm neonatal infants with respiratory distress syndrome (RDS). The studies were performed in 81 preterm neonates with severe RDS. For
S. A. Perepelitsa, A. M. Golubev, V. V. Moroz   +2 more
doaj   +1 more source

Altered surfactant homeostasis and recurrent respiratory failure secondary to TTF-1 nuclear targeting defect

Respiratory Research, 2011
Background Mutations of genes affecting surfactant homeostasis, such as SFTPB, SFTPC and ABCA3, lead to diffuse lung disease in neonates and children. Haploinsufficiency of NKX2.1, the gene encoding the thyroid transcription factor-1 (TTF-1) - critical ...
Carnielli Virgilio P, Stronati Mauro, Morini Francesco, Boldrini Renata, Tzialla Chryssoula, Petrini Stefania, Peca Donatella, Cogo Paola E, Danhaive Olivier   +8 more
doaj   +1 more source

Local lung hypoxia determines epithelial fate decisions during alveolar regeneration. [PDF]

, 2017
After influenza infection, lineage-negative epithelial progenitors (LNEPs) exhibit a binary response to reconstitute epithelial barriers: activating a Notch-dependent ΔNp63/cytokeratin 5 (Krt5) remodelling program or differentiating into alveolar type II
Brumwell, Alexis N, Chapman, Harold A, Driver, Ian H, Gotts, Jeffrey E, Jackson, Julia R, Kim, Thomas, Lee, Dong-Kee, Matthay, Michael A, Shannon, John M, Tan, Victor, Vaughan, Andrew E, Wei, Ying, Xi, Ying, Xu, Jianming   +13 more
core   +1 more source

Porcine versus bovine surfactant therapy for RDS in preterm neonates: pragmatic meta-analysis and review of physiopathological plausibility of the effects on extra-pulmonary outcomes

Respiratory Research, 2020
Background While porcine seems to be superior to bovine surfactants in terms of respiratory outcomes, it is unclear if a surfactant can improve extra-pulmonary outcomes in preterm neonates with respiratory distress syndrome and if there is any ...
Silvia Foligno, Daniele De Luca
doaj   +1 more source

Timing of initial surfactant treatment in very low birth weight newborns [PDF]

Einstein (São Paulo), 2010
Objective: To correlate the timing of treatment using exogenous surfactant with the main variables related to respiratory distress syndrome or prematurity.
Celso Moura Rebello, Luciene Ferreira do Amaral Nacif, Alice D´Agostini Deutsch, Ângela Tavares Paes   +3 more
doaj   +4 more sources