Results 21 to 30 of about 22,696 (353)

Pulmonary Surfactant and Drug Delivery: An Interface-Assisted Carrier to Deliver Surfactant Protein SP-D Into the Airways

Frontiers in Bioengineering and Biotechnology, 2021
This work is focused on the potential use of pulmonary surfactant to deliver full-length recombinant human surfactant protein SP-D (rhSP-D) using the respiratory air-liquid interface as a shuttle.
Cristina García-Mouton, Alberto Hidalgo, Raquel Arroyo, Mercedes Echaide, Antonio Cruz, Jesús Pérez-Gil   +5 more
doaj   +1 more source

EXOGENOUS SURFACTANTS OF NATURAL ORIGIN IN THE TREATMENT OF RESPIRATORY DISTRESS SYNDROME - COMPARATIVE COMPOSITION, BIOPHYSICAL PROPERTIES AND CLINICAL EFFECTIVENESS

Неонатологія, хірургія та перинатальна медицина, 2020
Respiratory distress syndrome (RDS) remains an important cause of morbidity and mortality in premature infants in Ukraine and around the world. Since the determination of surfactant deficiency as the main cause of this disease, significant progress has ...
D.О. Dobryanskyy
doaj   +1 more source

Surfactant function in neonates with respiratory distress syndrome [PDF]

, 1998
The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was ...
Griese, Matthias, Westerburg, Bettina
core   +1 more source

Pulmonary Surfactant Preparations and Surfactant Therapy for ARDS in Surgical Intensive Care (a Literature Review)

Креативная хирургия и онкология, 2019
Introduction. Despite the fact that clinical studies of pulmonary surfactants conducted over many years have demonstrated their efficacy for the treatment of acute respiratory distress syndrome (ARDS) which led to their approval for use inRussia ...
O. A. Rosenberg
doaj   +1 more source

Thermodynamically consistent description of the hydrodynamics of free surfaces covered by insoluble surfactants of high concentration [PDF]

, 2012
In this paper we propose several models that describe the dynamics of liquid films which are covered by a high concentration layer of insoluble surfactant.
Adamson A. W., Andrew J. Archer, Atkins P., Henderson D., Israelachvili J. N., Langer J. S., Manteuffel E. S. K., Mathis Plapp, Uwe Thiele   +8 more
core   +3 more sources

Inhaled Insulin: Intrapulmonary or Intranasal? [PDF]

, 2012
Initial attempts delivered the insulin hormone intramuscularly, intravenously, and eventually subcutaneously. Other routes of administration of the drug were explored.
Danish Ahmed, Shivangi Jaiswal, Shruti Mishra, Sweta Kumari   +3 more
core   +2 more sources

Bio-inspired pulmonary surfactant-modified nanogels : a promising siRNA delivery system [PDF]

, 2015
Inhalation therapy with small interfering RNA (siRNA) is a promising approach in the treatment of pulmonary disorders. However, clinical translation is severely limited by the lack of suitable delivery platforms.
Braeckmans, Kevin, De Backer, Lynn, De Smedt, Stefaan, Demeester, Jo, Raemdonck, Koen, Stuart, Marc CA   +5 more
core   +3 more sources

Impact of Polymer Nanoparticles on DPPC Monolayer Properties

Colloids and Interfaces, 2022
The application of surface rheology and Brewster angle microscopy on mixed monolayers of DPPC and polymeric nanoparticles (cationic and anionic) showed that the sign of the particle charge affects the dynamic properties of the monolayers less than the ...
Alexey Bykov, Olga Milyaeva, Alexander Akentiev, Maria Panaeva, Nikolaj Isakov, Reinhard Miller, Boris Noskov   +6 more
doaj   +1 more source

Ionic Surface Active Compounds in Atmospheric Aerosols

The Scientific World Journal, 2002
Surfactants in the atmosphere have several potential roles in atmospheric chemistry. They can form films on aqueous surfaces, which lowers the surface tension and possibly delays water evaporation and gaseous transportation across the aqueous interface ...
Jariya Sukhapan, Peter Brimblecombe
doaj   +1 more source

Synthesis, Structure–Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers

Pharmaceutics, 2018
Permeability enhancers are receiving increased attention arising from their ability to increase transepithelial permeability and thus, bioavailability of orally or pulmonary administered biopharmaceutics.
Simone Lucarini, Laura Fagioli, Robert Cavanagh, Wanling Liang, Diego Romano Perinelli, Mario Campana, Snjezana Stolnik, Jenny K. W. Lam, Luca Casettari, Andrea Duranti   +9 more
doaj   +1 more source