Results 31 to 40 of about 22,696 (353)

Nanoparticles in the treatment of chronic lung diseases [PDF]

, 2019
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G, Cosnarovici, Maria, Negrean, Vasile, Orasan, Olga H, Para, Ioana, Perne, Mirela G, Popovici, Ionela, Ruta, Victoria M, Tarmure, Simina, Todea, Doina A   +9 more
core   +2 more sources

Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part I)

Общая реаниматология, 2014
Part 1 of the review gives information on the composition and properties of a pulmonary surfactant and quantitative and qual itative impairments in the pulmonary surfactant system in different neonatal and adult abnormalities and describes the ...
O. A. Rozenberg
doaj   +1 more source

In vitro characterization and in vivo comparison of the pulmonary outcomes of Poractant alfa and Calsurf in ventilated preterm rabbits.

PLoS ONE, 2020
Poractant alfa and Calsurf are two natural surfactants widely used in China for the treatment of neonatal respiratory distress syndrome, which are extracted from porcine and calf lungs, respectively.
Xiaojing Guo, Siwei Luo, Davide Amidani, Claudio Rivetti, Giuseppe Pieraccini, Barbara Pioselli, Silvia Catinella, Xabi Murgia, Fabrizio Salomone, Yaling Xu, Ying Dong, Bo Sun   +11 more
doaj   +1 more source

Hydrophobic double walled carbon nanotubes interaction with phopholipidic model membranes: 1H-, 2H-, 31P NMR and ESR study [PDF]

, 2010
The interactions of carbon nanotubes synthesized by catalytic chemical vapour deposition with phospholipidic bilayers, mimicking biological membranes, have been investigated using solid state 31P- and 2H NMR, 1H- and 31P NMR in liquids and ESR studies ...
Crouzier, David, Debouzy, Jean-Claude, Flahaut, Emmanuel   +2 more
core   +1 more source

The melting of pulmonary surfactant monolayers [PDF]

Journal of Applied Physiology, 2007
Monomolecular films of phospholipids in the liquid-expanded (LE) phase after supercompression to high surface pressures (π), well above the equilibrium surface pressure (πe) at which fluid films collapse from the interface to form a three-dimensional bulk phase, and in the tilted-condensed (TC) phase both replicate the resistance to collapse that is ...
Wenfei Yan, Stephen B. Hall, Ted Laderas, Samares C. Biswas   +3 more
openaire   +3 more sources

A finite membrane element formulation for surfactants

, 2019
Surfactants play an important role in various physiological and biomechanical applications. An example is the respiratory system, where pulmonary surfactants facilitate the breathing and reduce the possibility of airway blocking by lowering the surface ...
Roohbakhshan, Farshad, Sauer, Roger A.
core   +1 more source

Budesonide/formoterol enhances the expression of pro Surfactant Protein-B in lungs of COPD patients. [PDF]

PLoS ONE, 2013
Pulmonary surfactants are essential components of lung homeostasis. In chronic obstructive pulmonary disease (COPD), surfactant expression decreases in lungs whereas, there is a paradoxical increase in protein expression in plasma.
Soo Jung Um, Stephen Lam, Harvey Coxson, Shu Fan Paul Man, Don D Sin   +4 more
doaj   +1 more source

YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1

iScience, 2021
Summary: Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as ...
Jason J. Gokey, John Snowball, Anusha Sridharan, Parvathi Sudha, Joseph A. Kitzmiller, Yan Xu, Jeffrey A. Whitsett   +6 more
doaj   +1 more source

Biomedical and therapeutic applications of biosurfactants [PDF]

, 2010
During the last years, several applications of biosurfactants with medical purposes have been reported. Biosurfactants are considered relevant molecules for applications in combating many diseases and as therapeutic agents due to their antibacterial ...
A. Bernheimer, A. Fiechter, A. Flasz, A. Singh, A.B. Moldes, A.L. Moyne, B. Angelova, B. Gan, C. Carrillo, C. Delden Van, C. Heinemann, C.G. Hoogmoed Van, C.L. Wang, C.N. Mulligan, D. Kitamoto, D. Kitamoto, D. Vollenbroich, D. Vollenbroich, D.J. Bidel, D.R. Mack, F. Ahimou, F. Besson, F. Ramisse, G. Reid, G. Reid, G. Reid, G. Reid, G. Reid, H. Isoda, H. Isoda, H. Itokawa, H. Sano, H.J. Busscher, H.J. Busscher, H.J. Busscher, I. Grangemard, I.M. Banat, I.M. Banat, I.M. Banat, I.N.A. Bogaert Van, J. Gerard, J. Im, J.D. Desai, J.D. Hamme Van, J.D. Sheppard, J.H. Im, J.R. Mireles, J.R. Wright, K. Das, K. Das, K. Jenny, K. Kim, K. Millsap, K. Mittenbuhler, L. Thimon, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, M. Benincasa, M. Konishi, M. Morikawa, M. Shibahara, M. Velraeds, M. Velraeds, M. Velraeds, M. Velraeds, M. Yakimov, N. G. Dehghan, N. Kosaric, N. Kosaric, N. Naruse, O.M.P. Rivera, P. Gotek, P. Singh, R. Maier, R. Makkar, R. Sen, R.M. Maier, R.T. Otto, S. Boris, S. Cameotra, S. Cameotra, S. Igarashi, S. Ito, S. Joshi, S. Lang, S. Lin, S. Lin, S. Mukherjee, T. I. Pratt, T. Kikuchi, T. Kikuchi, T. Neu, T. Nielsen, T. Sudo, V. Shah, X. Zhao, X. Zhao, Y. Inoh, Y. Inoh, Y. Ishigami, Y. Kameda, Y. Maitani, Y. Tanaka, Y. Uchida, Y. Uchida, Y. Ueno, Y. Ueno, Y. Wakamatsu   +114 more
core   +1 more source

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

Mediators of Inflammation, 2021
Causes of mortality from COVID-19 include respiratory failure, heart failure, and sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that recognizes pathogen-associated molecular patterns (PAMPs) including viral proteins and
Mohamed M. Aboudounya, Richard J. Heads
doaj   +1 more source