Results 41 to 50 of about 22,696 (353)

The structure of latherin, a surfactant allergen protein from horse sweat and saliva [PDF]

, 2013
Latherin is a highly surface-active allergen protein found in the sweat and saliva of horses and other equids. Its surfactant activity is intrinsic to the protein in its native form, and is manifest without associated lipids or glycosylation.
Alan Cooper, Brian O. Smith, Lamping N, Malcolm W. Kennedy, Rhona E. McDonald, Steven J. Vance, Vance SJ   +6 more
core   +1 more source

The role of lipids in pulmonary surfactant

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1998
Pulmonary surfactant is composed of approx. 90% lipids and 10% protein. This review article focusses on the lipid components of surfactant. The first sections will describe the lipid composition of mammalian surfactant and the techniques that have been utilized to study the involvement of these lipids in reducing the surface tension at an air-liquid ...
Veldhuizen, Ruud, Nag, Kaushik, Orgeig, Sandra, Possmayer, Fred   +3 more
openaire   +5 more sources

Pulmonary Surfactant: An Immunological Perspective [PDF]

Cellular Physiology and Biochemistry, 2010
Pulmonary surfactant has two crucial roles in respiratory function; first, as a biophysical entity it reduces surface tension at the air water interface, facilitating gas exchange and alveolar stability during breathing, and, second, as an innate component of the lung's immune system it helps maintain sterility and balance immune reactions in the ...
Virginia L. Shepherd, Zvjezdana Sever-Chroneos, Zissis C. Chroneos   +2 more
openaire   +3 more sources

A case of autoimmune pulmonary alveolar proteinosis with severe respiratory failure treated with segmental lung lavage and oral statin therapy

Respiratory Medicine Case Reports, 2022
Pulmonary alveolar proteinosis (PAP) is a diffuse lung disease characterized by the accumulation of alveolar surfactants due to dysfunction of granulocyte-macrophage colony-stimulating factor-dependent cholesterol clearance.
Tomotsugu Takano, Keisuke Takeda, Satoshi Nakamura, Genta Akiyama, Nobuhisa Ando, Masashi Komori   +5 more
doaj   +1 more source

The biophysical function of pulmonary surfactant [PDF]

Respiratory Physiology & Neurobiology, 2008
Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two key aspects of this function: that the surfactant film forms rapidly; and that when compressed by the shrinking alveolar area during exhalation, the film reduces surface tension to very low values.
Sandra Rugonyi, Stephen B. Hall, Samares C. Biswas   +2 more
openaire   +3 more sources

Unraveling the enigma: The emerging significance of pulmonary surfactant proteins in predicting, diagnosing, and managing COVID‐19

Immunity, Inflammation and Disease
Background Severe cases of COVID‐19 often lead to the development of acute respiratory syndrome, a critical condition believed to be caused by the harmful effects of SARS‐CoV‐2 on type II alveolar cells.
Mohammad Navid Bastani, Shahram Jalilian
doaj   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Effect of exogenous surfactant on Paediatric Bronchoalveolar lavage derived macrophages’ cytokine secretion

BMC Pulmonary Medicine, 2019
Background Bronchoalveolar lavage is a useful bronchoscopy technique. However, studies in “normal” children populations are few. Furthermore, the anti-inflammatory effects of exogenous pulmonary surfactants on the bronchoalveolar cellular components are ...
Lyné van Rensburg, Johann M. van Zyl, Johan Smith, Pierre Goussard   +3 more
doaj   +1 more source

A Deeper Insight into the Interfacial Behavior and Structural Properties of Mixed DPPC/POPC Monolayers: Implications for Respiratory Health

Membranes, 2022
1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1-palmitoyl-2-oleyl-sn-glycerol-3-phosphorcholine (POPC) are important components in pulmonary surfactants (PSs), of which the relative content is related to lung compliance.
Yingxue Geng, Yan Cao, Yingjie Li, Qun Zhao, Dan Liu, Ge Fan, Senlin Tian   +6 more
doaj   +1 more source

The Marangoni flow of soluble amphiphiles

, 2013
Surfactant distribution heterogeneities at a fluid/fluid interface trigger the Marangoni effect, i.e. a bulk flow due to a surface tension gradient. The influence of surfactant solubility in the bulk on these flows remains incompletely characterized ...
Cantat, Isabelle, Griffiths, Ian M., Li, Zhenzhen, Roché, Matthieu, Roux, Sébastien Le, Saint-Jalmes, Arnaud, Stone, Howard A.   +6 more
core   +3 more sources