Results 41 to 50 of about 13,172 (206)

A Deeper Insight into the Interfacial Behavior and Structural Properties of Mixed DPPC/POPC Monolayers: Implications for Respiratory Health

open access: yesMembranes, 2022
1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1-palmitoyl-2-oleyl-sn-glycerol-3-phosphorcholine (POPC) are important components in pulmonary surfactants (PSs), of which the relative content is related to lung compliance.
Yingxue Geng   +6 more
doaj   +1 more source

Strategies to Enhance Drug Absorption via Nasal and Pulmonary Routes

open access: yesPharmaceutics, 2019
New therapeutic agents such as proteins, peptides, and nucleic acid-based agents are being developed every year, making it vital to find a non-invasive route such as nasal or pulmonary for their administration.
Maliheh Ghadiri   +2 more
doaj   +1 more source

Early versus late extubation after surfactant replacement therapy for respiratory distress syndrome

open access: yesEgyptian Pediatric Association Gazette, 2015
Patients and methods: Ninety patients treated by surfactant replacement therapy were included in the study. Patients were divided into 2 groups; group A consists of patients who were extubated early within 24 h after surfactant administration and group B
Mohamed Garib   +2 more
doaj   +1 more source

Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part II)

open access: yesОбщая реаниматология, 2014
Part 2 of the review considers the problem of surfactant therapy for acute respiratory distress syndrome (ARDS) in adults and young and old children. It gives information on the results of surfactant therapy and prevention of ARDS in patients with severe
O. A. Rozenberg
doaj   +1 more source

Formulation Strategies of Nanosuspensions for Various Administration Routes

open access: yesPharmaceutics, 2023
Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently become one of the most interesting substances in nanopharmaceuticals.
Sıla Gülbağ Pınar   +3 more
doaj   +1 more source

Exogenous surfactant for lung contusion causing ARDS: A systematic review of clinical and experimental reports

open access: yesThe Clinical Respiratory Journal
This systematic review aimed to summarize the available data on the treatment of pulmonary contusions with exogenous surfactants, determine whether this treatment benefits patients with severe pulmonary contusions, and evaluate the optimal type of ...
Tomáš Merkl   +7 more
doaj   +1 more source

Systematic Analysis of Composition, Interfacial Performance and Effects of Pulmonary Surfactant Preparations on Cellular Uptake and Cytotoxicity of Aerosolized Nanomaterials

open access: yesSmall Science, 2021
The interplay of particles with pulmonary surfactant, a lipid‐protein material pivotal for lung function, is hypothesized as a key factor that has not been routinely considered in the current in vitro models when determining the fate of inhaled ...
Benedikt Huck   +12 more
doaj   +1 more source

Lipid-Laden Macrophages in Pulmonary Diseases

open access: yesCells
Pulmonary surfactants play a crucial role in managing lung lipid metabolism, and dysregulation of this process is evident in various lung diseases. Alternations in lipid metabolism lead to pulmonary surfactant damage, resulting in hyperlipidemia in ...
Yin Zhu   +3 more
doaj   +1 more source

Comparison of the efficacy of two natural surfactants (BERAKSURF and BLES) in the treatment of respiratory distress syndrome among preterm neonates

open access: yesBMC Pediatrics, 2023
Background The benefit of surfactant replacement therapy for respiratory distress syndrome (RDS) has been demonstrated. However, some surfactants are expensive and usually inaccessible.
Fatemeh Sabzevari   +5 more
doaj   +1 more source

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