Results 51 to 60 of about 13,172 (206)

Aerosol delivery of dry powder synthetic lung surfactant to surfactant-deficient rabbits and preterm lambs on non-invasive respiratory support [version 1; referees: 3 approved]

Gates Open Research, 2019
Background: The development of synthetic lung surfactant for preterm infants has focused on peptide analogues of native surfactant proteins B and C (SP-B and SP-C).
Frans J. Walther, Monik Gupta, Michael M. Lipp, Holly Chan, John Krzewick, Larry M. Gordon, Alan J. Waring   +6 more
doaj   +1 more source

A multicenter, randomized, double-blind trial of a new porcine surfactant in premature infants with respiratory distress syndrome

Einstein (São Paulo)
Objective To compare the efficacy and safety of a new porcine-derived pulmonary surfactant developed by Instituto Butantan with those of animal-derived surfactants commercially available in Brazil, regarding neonatal mortality and the major complications
Celso Moura Rebello, Alexander Roberto Precioso, Renata Suman Mascaretti   +2 more
doaj   +1 more source

Aerosol delivery of dry powder synthetic lung surfactant to surfactant-deficient rabbits and preterm lambs on non-invasive respiratory support [version 2; referees: 3 approved]

Gates Open Research, 2019
Background: The development of synthetic lung surfactant for preterm infants has focused on peptide analogues of native surfactant proteins B and C (SP-B and SP-C).
Frans J. Walther, Monik Gupta, Michael M. Lipp, Holly Chan, John Krzewick, Larry M. Gordon, Alan J. Waring   +6 more
doaj   +1 more source

Deleted in Malignant Brain Tumors 1 (DMBT1) is present in hyaline membranes and modulates surface tension of surfactant

Respiratory Research, 2007
Background Deleted in Malignant Brain Tumors 1 (DMBT1) is a secreted scavenger receptor cysteine-rich protein that binds various bacteria and is thought to participate in innate pulmonary host defense.
Griese Matthias, Hartl Dominik, Weiss Christel, Gassler Nikolaus, Helmke Burkhard M, Renner Marcus, End Caroline, Müller Hanna, Hafner Mathias, Poustka Annemarie, Mollenhauer Jan, Poeschl Johannes   +11 more
doaj   +1 more source

Comparative efficacy of pulmonary surfactant in respiratory distress syndrome in preterm infants: a Bayesian network meta-analysis

Archives of Medical Science, 2020
Introduction The comparative efficacy of pulmonary surfactant in the treatment of respiratory distress syndrome in preterm infants remains unclear. We aimed to evaluate the effectiveness of different pulmonary surfactant in the treatment of respiratory ...
Caihong Qiu, Cui Ma, Nana Fan, Xiaoyu Zhang, Guofeng Zheng   +4 more
doaj   +1 more source

Potential Therapeutic Applications of Pulmonary Surfactant Lipids in the Host Defence Against Respiratory Viral Infections [PDF]

, 2021
Jianjian Ji, Ling Sun, Zichen Luo, Ying Zhang, Xianzheng Wang, Yingzhao Liao, Tong Xie, Jinjun Shan   +7 more
openalex   +1 more source

Persistent pulmonary hypertension of the newborn

Journal of the Formosan Medical Association, 2013
Persistent pulmonary hypertension of the newborn (PPHN) is a severe pulmonary disorder which occurs at a rate of one in every 500 live births. About 10–50% of the victims will die of the problem and 7–20% of the survivors develop long-term impairments ...
Ru-Jeng Teng, Tzong-Jin Wu
doaj   +1 more source

The effect of a peptide-containing synthetic lung surfactant on gas exchange and lung mechanics in a rabbit model of surfactant depletion

Drug Design, Development and Therapy, 2013
Johann M van Zyl,1 Johan Smith,2 Arthur Hawtrey1 1Division of Pharmacology, 2Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa Background: Currently, a new generation of synthetic pulmonary surfactants is being ...
van Zyl JM, Smith J, Hawtrey A
doaj  

Deuterium‐depleted water: A new tracer to label pulmonary surfactant lipids in adult rabbits [PDF]

, 2022
Manuela Simonato, Francesca Ricci, Chiara Catozzi, Matteo Storti, Sonia Giambelluca, Alessio Correani, Fabrizio Salomone, Paola Cogo, Virgilio Carnielli   +8 more
openalex   +1 more source

Interfacial structure of pulmonary surfactants revisited: Cholesterol and surface pressure effects. [PDF]

Biophys J, 2022
Nylander T.
europepmc   +1 more source