Results 71 to 80 of about 1,349,045 (346)
Small Science, 2021 The interplay of particles with pulmonary surfactant, a lipid‐protein material pivotal for lung function, is hypothesized as a key factor that has not been routinely considered in the current in vitro models when determining the fate of inhaled ...
Benedikt Huck +12 more
doaj +1 more source
Surfactants: past, present and future
Journal of Perinatology, 2008 In 1929 Kurt von Neergaard performed experiments suggesting the presence of pulmonary surfactant and its relevance to the newborn's first breath. Almost 25 years later, Richard Pattle, John Clements and Chris Macklin, each working on the effects of nerve
H. L. Halliday
semanticscholar +1 more source
Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium. [PDF]
, 2018 Lung epithelial lineages have been difficult to maintain in pure form in vitro, and lineage-specific reporters have proven invaluable for monitoring their emergence from cultured pluripotent stem cells (PSCs).
Alysandratos, Konstantinos-Dionysios +14 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao +4 more
wiley +1 more source
Lipid-Laden Macrophages in Pulmonary Diseases
CellsPulmonary surfactants play a crucial role in managing lung lipid metabolism, and dysregulation of this process is evident in various lung diseases. Alternations in lipid metabolism lead to pulmonary surfactant damage, resulting in hyperlipidemia in ...
Yin Zhu +3 more
doaj +1 more source
BMC Pediatrics, 2023 Background The benefit of surfactant replacement therapy for respiratory distress syndrome (RDS) has been demonstrated. However, some surfactants are expensive and usually inaccessible.
Fatemeh Sabzevari +5 more
doaj +1 more source
Gas-liquid hydrodynamics in Taylor Flows with complex liquids [PDF]
, 2010 Universitá di Pisa Facoltá di Ingegneria Dipartimento di Ingegneria Chimica, Chimica Industriale e Scienza dei Materiali Relazione di tirocinio in Ingegneria Chimica Gas-liquid hydrodynamics in Taylor Flows with complex liquids Il candidato: Federico ...
ALBERINI, FEDERICO
core
A model of flow and surfactant transport in an oscillatory alveolus partially filled with liquid [PDF]
, 2005 The flow and transport in an alveolus are of fundamental importance to partial liquid ventilation, surfactant transport, pulmonary drug administration, cell-cell signaling pathways, and gene therapy.
Fujioka, Hideki +3 more
core +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Spreading of a surfactant monolayer on a thin liquid film: Onset and evolution of digitated structures [PDF]
, 1999 We describe the response of an insoluble surfactant monolayer spreading on the surface of a thin liquid film to small disturbances in the film thickness and surfactant concentration.
Matar, Omar K., Troian, Sandra M.
core +1 more source