Results 81 to 90 of about 4,197,466 (259)

Echocardiographic assessment of pulmonary vascular resistance in pulmonary arterial hypertension

Cardiovascular Ultrasound, 2010
Background Echocardiographic ratio of peak tricuspid regurgitant velocity to the right ventricular outflow tract time-velocity integral (TRV/TVI rvot) was presented as a reliable non-invasive method of estimating pulmonary vascular resistance (PVR ...
Bergot Emmanuel, Gomes Sophie, Lognoné Thérèse, Sabatier Rémi, Pellissier Arnaud, Labombarda Fabien, Roule Vincent, Milliez Paul, Grollier Gilles, Saloux Eric   +9 more
doaj   +1 more source

Peripheral pulmonary vascular resistance

, 1993
The pressure-flow relationship has been studied in a peripheral portion of the lung vasculature in anesthetized dogs with use of a double-lumen catheter wedged in a distal pulmonary artery.
C. Saunier, F. Chabot, F. Schrijen
core   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Characterization of thromboxane and prostacyclin effects on pulmonary vascular resistance

, 1992
Although thromboxane and prostacyclin (PGI2) have long been described as major controllers of pulmonary vascular resistance, little has been reported on the characteristics of the interactions between the two arachidonic acid products. The current study
A. E. Taylor, W. K. Adkins, R. A. Ward, J. W. Barnard   +3 more
core   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Role of the soluble epoxide hydrolase and cytochrome P450-derived epoxyeicosatrienoic acids in hypoxic pulmonary vasoconstriction and hypoxia-induced pulmonary vascular remodelling [PDF]

, 2009
Hypoxic pulmonary vasoconstriction (HPV) redistributes pulmonary blood flow from areas of low oxygen partial pressure to areas of normal or relativity high oxygen availability, thus optimising the matching of perfusion to ventilation and preventing ...
Keserü, Benjamin
core  

Pulmonary Vascular Hemodynamic Risk Factors in Early Survivors and Non-survivors of Surgical Patients with Intracardiac Shunts.

, 2014
PVRI, pulmonary vascular resistance index; PVRIO, pulmonary vascular resistance index on pure oxygen challenge; PVRID, difference between PVRI and PVRIO; Qp∶Qs, pulmonary to systemic flow ratio; Rp∶Rs, ratio of pulmonary and systemic vascular resistance;
Hui-Li Gan (435704), Fei Chen (13690), Jian-Qun Zhang (504097), Lei Feng (122689), Qi-Wen Zhou (506960), Yi Yang (116183)   +5 more
core   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

The α and Δ isoforms of CREB1 are required to maintain normal pulmonary vascular resistance.

PLoS ONE, 2013
Chronic hypoxia causes pulmonary hypertension associated with structural alterations in pulmonary vessels and sustained vasoconstriction. The transcriptional mechanisms responsible for these distinctive changes are unclear.
Lili Li, Katherine Howell, Michelle Sands, Mark Banahan, Stephen Frohlich, Simon C Rowan, Roisín Neary, Donal Ryan, Paul McLoughlin   +8 more
doaj   +1 more source

Survival curves according to the optimal cut-off value derived by ROC analysis for preoperative pulmonary vascular resistance (PVR).

, 2018
Survival curves according to the optimal cut-off value derived by ROC analysis for preoperative pulmonary vascular resistance (PVR).
Mitja Jevnikar (5434952), Xavier Jaïs (5220773), Francis Couturaud (821892), Sacha Mussot (647274), Cécile Tromeur (821891), Elie Fadel (471021), Jason Weatherald (5220770), Olivier Sitbon (777335), David Montani (467016), Florence Parent (5434946), Marc Humbert (23466), Dominique Fabre (5434949), Laurent Savale (777333), Gérald Simonneau (4722351), Philippe Dartevelle (471020), Olaf Mercier (471015)   +15 more
core   +1 more source