ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang +5 more
wiley +1 more source
VPA Enhances Pulp Regeneration by Regulating LPS-Induced Human Dental Pulp Stem Cells Odontogenic Differentiation. [PDF]
Wang Z +12 more
europepmc +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
ECM remodeling by PDGFRβ+ dental pulp stem cells drives angiogenesis and pulp regeneration via integrin signaling. [PDF]
Di T +9 more
europepmc +1 more source
Solitary Bone Cysts of the Anterior Mandible: Systematic Review and Presentation of Two Cases
ABSTRACT Background Solitary bone cysts (SBCs) are non‐epithelialized intraosseous cavities that predominantly affect the posterior mandible of children and young adults. Their occurrence in the anterior mandible is uncommon, and available data remain limited.
Qendresa Lubishtani +4 more
wiley +1 more source
A Comparison Between Three Types of Scaffolds for Pulp Regeneration: A Histological Study on Dogs. [PDF]
Alshahhoud A +4 more
europepmc +1 more source
660‐nm photobiomodulation increased metabolic activity, modulated cell cycle distribution, and increased apparent surface coverage in dental stem cells cultured on polylactic acid films, with 4 J/cm2 producing the most consistent response and a greater G2/M fraction than 1 J/cm2.
Rômulo Augusto de Paiva Macedo +5 more
wiley +1 more source
The Hippo-YAP/β-catenin signaling axis coordinates odontogenic differentiation in dental pulp stem cells: Implications for dentin-pulp regeneration. [PDF]
Chen C +5 more
europepmc +1 more source
Abstract In patients with advanced periodontal disease, pathological tooth migration may occur, which may require subsequent orthodontic treatment for both aesthetic and functional purposes. When planning orthodontic treatment mechanics, intrusive or extrusive forces are frequently indicated.
Gregory S. Antonarakis +3 more
wiley +1 more source
Neovascularization by DPSC-ECs in a Tube Model for Pulp Regeneration Study. [PDF]
Zhang Y +5 more
europepmc +1 more source

