Results 11 to 20 of about 545 (146)

Advancing Sulfinyl Radical Chemistry: An Asymmetric Smiles Rearrangement with Chiral Sulfoxides. [PDF]

Angew Chem Int Ed Engl
A visible‐light‐driven, asymmetric sulfinyl‐Smiles rearrangement enables the enantioselective trifunctionalization of chiral sulfoxides via radical addition, 1,5‐aryl migration, and sulfinyl radical interception. By tuning the redox potentials of key components, this cascade forms two C─C and one C─S bond in a single step, yielding enantioenriched ...
Hu Y, Schreyer T, Nevado C.
europepmc   +3 more sources

Synthetic Strategies to Access Fluorinated Azoles. [PDF]

European J Org Chem
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
El-Gaber MKA, Djugovski M, Huang TY, Adhikari S, Roy S.   +4 more
europepmc   +2 more sources

New Glycoconjugates Containing Selenium and Polyphenols. Stereoselective Synthesis by Pummerer‐like Rearrangement. [PDF]

European Journal of Organic Chemistry, Volume 28, Issue 26, July 12, 2025.
Two series of novel six‐membered Se‐glycoconjugates containing hydroxycinnamic acids marked by well‐known antioxidant properties are synthesized, exploiting a Mitsunobu reaction and a Pummerer‐like rearrangement. A first example of six‐membered selenosugar with selenium in the ring and bearing an acetal‐like functional group at C‐1 was reported, which ...
Claudia González, Mauro De Nisco, Reinier Lemos, Giovanna Cimmino, Yoana Pérez‐Badell, Severina Pacifico, Silvana Pedatella   +6 more
openalex   +2 more sources

Pummerer fragmentation vs. Pummerer rearrangement: a mechanistic analysis

Chemical Communications, 2006
Depending upon the nature of the substituent at the beta-position of the sulfoxide moiety, a Pummerer reaction can be oriented "at will" towards Calpha-H (rearrangement) or Calpha-Cbeta (fragmentation) bond cleavage.
Laleu, Benoît, Machado, Marco Santarem, Lacour, Jérôme   +2 more
openaire   +3 more sources

Novel synthesized seleno-glycoconjugates as cosmeceutical ingredients: Antioxidant activity and in vitro skin permeation

European Journal of Medicinal Chemistry Reports
Following recent successful results in the search for innovative semi-synthetic cosmeceutical Se-glycoconjugates, the work reported herein explores the development and evaluation of second-generation selenosugar-linked hydroxycinnamic acids as new ...
Giovanna Cimmino, Mauro De Nisco, Cristina Alonso, Claudia Gravina, Vincenzo Piscopo, Reinier Lemos, Luisa Coderch, Simona Piccolella, Severina Pacifico, Silvana Pedatella   +9 more
doaj   +1 more source

Regioselective Pummerer rearrangement in [2.2]paracyclophanes

Phosphorus, Sulfur, and Silicon and the Related Elements, 2020
We investigated and rationalized a synthetic pathway to [2.2]paracyclophanedienes, that exploits the combination of the Pummerer rearrangement on a dithiacyclophane with a photochemical sulfur extrusion step and a base-catalyzed elimination step. The synthetic pathway is very effective for the symmetric, prototypical [2.2]paracyclophanediene.
Invernizzi F., Nitti A., Pasini D.
openaire   +2 more sources

Thiophene Derivatives as Versatile Precursors for (Hetero)Arene and Natural Product Synthesis

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Hidden but Powerful: Thiophenes and their saturated analogues have been demonstrated to be versatile C4‐building blocks that can be rapidly applied to natural product synthesis and the construction of functionalized (hetero)arenes. This minireview aims to provide a concise overview of the strategies and implementations of these sulfur‐containing ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Philipp Natho, Annarita Vicenti, Fabrizio Mastrolorito, Francesca De Franco, Lee Walsh‐Benn, Marco Colella, Ernesto Mesto, Emanuela Schingaro, Orazio Nicolotti, Antimo Gioiello, Renzo Luisi   +10 more
wiley   +1 more source

Asymmetric [3,3]‐Sigmatropic Rearrangement for the Synthesis of Quaternary Center‐Containing Polycyclic Molecules: Application to the Total Synthesis of Myrmenaphthol A

ChemistryEurope, Volume 4, Issue 1, January 2026.
A small library of tricyclic natural product‐like molecules with quaternary stereocenters is rapidly synthesized. An excellent chirality transfer from sulfur to carbon atom is observed, furnishing the desired products in 90–99% enantiomeric excesses and 51–78% isolated yields.
Weiping Zhou, Gia Hao Huynh, Arnaud Voituriez   +2 more
wiley   +1 more source

STEREOSELECTIVE PUMMERER REARRANGEMENT OF PHENYLSULFINYLCYCLOPROPANES WITH ACETIC ANHYDRIDE [PDF]

Chemistry Letters, 1977
Abstract The Pummerer reaction of cis- and trans-2-phenyl-1-(phenylsulfinyl)cyclopropanes and cis, syn- and cis, anti-2,3-dimethyl-1-(phenylsulfinyl)cyclopropanes afforded the stereoselective products.
Toshiaki Masuda, Tatsuo Numata, Naomichi Furukawa, Shigeru Oae   +3 more
openaire   +1 more source