Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection [PDF]
Advanced ScienceMycobacterium abscessus (MAB) is an increasingly recognized rapidly growing nontuberculous mycobacterial pathogen whose infection is particularly challenging to treat due to its antibiotic resistance and persistence, necessitating the exploration of ...
Kefan Bi +4 more
doaj +2 more sources
Optimization of pulsed ultrasound-assisted technique for extraction of phenolics from pomegranate peel of Malas variety: Punicalagin and hydroxybenzoic acids [PDF]
Food Chemistry, 2016 Pomegranate peel is a rich source of phenolic compounds (such as punicalagin and hydroxybenzoic acids). However, the content of such bioactive compounds in the peel extract can be affected by extraction type and condition.
Milad Kazemi +2 more
exaly +3 more sources
Integrated Phenotypic and Transcriptomic Analyses Unveil the Antibacterial Mechanism of Punicalagin Against Methicillin-Resistant Staphylococcus aureus (MRSA) [PDF]
FoodsThe growing emergence of multidrug-resistant bacterial pathogens drives the need for new antibacterial agents. Punicalagin exhibits efficacy against methicillin-resistant Staphylococcus aureus (MRSA), but its specific antibacterial mechanisms remain ...
Yiming Wang +7 more
doaj +2 more sources
Antimicrobial and Immunomodulatory Effects of Punicalagin and Meropenem in a Murine Model of Sublethal Sepsis [PDF]
AntibioticsBackground: Punicalagin (Pg), a major ellagitannin derived from pomegranates, possesses antimicrobial, antioxidant, and immunomodulatory properties, suggesting its potential as an adjunctive therapy for sepsis.
Liliane dos Santos Rodrigues +7 more
doaj +2 more sources
Effects of Adding Punicalagin or Oleuropein to TRIS Diluent on Quality of Frozen–Thawed Semen from Rams [PDF]
AnimalsThis study aimed to investigate the effects of adding different levels of punicalagin or oleuropein to TRIS diluent on the quality of frozen–thawed semen from Najdi rams.
Mohamed Shehab-El-Deen +6 more
doaj +2 more sources
Study on the Effects of Tannase on the De Astringency of Pomegranate Juice [PDF]
FoodsReducing the punicalagin content is an effective strategy for eliminating the astringency of pomegranate juice. In this study, pomegranate juice was used as the raw material, and tannase was applied to convert punicalagin into ellagic acid and gallic ...
Guida Zhu +7 more
doaj +2 more sources
Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia [PDF]
PeerJ, 2021 Background Punicalagin is the major phenolic compound found in pomegranate peels. It has several reported medical benefits, including antioxidant, anti-inflammatory, and anticancer properties.
Paweena Subkorn +3 more
doaj +2 more sources
Pharmaceutical Biology, 2023 Context Punicalagin has myocardial protection; the mechanism of punicalagin on ventricular remodeling (VR) after acute myocardial infarction (AMI) remains unclear.Objective These studies explore the role and mechanism of punicalagin in preventing and ...
Jian-fei Peng +9 more
doaj +1 more source
Translational Oncology, 2022 Punicalagin, which is derived from pomegranate peel, is reported to exert growth-inhibitory effects against various cancers. However, the underlying mechanisms have not been elucidated.
Xialin Xie +9 more
doaj +1 more source
Biomedicines, 2021 In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity.
Giuliano Paglia +7 more
doaj +1 more source