Antifungal potential of punicalagin against Cryptococcus neoformans species complex [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2018 This study evaluated the antifungal activity and cytotoxicity profile of the ellagitannin punicalagin, a compound extracted from the L. pacari A. St.-Hil (Lythraceae) leaf, against Cryptococcus neoformans species complex.
Thaísa Cristina Silva +9 more
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Antimicrobial Activity and Mechanisms of Punicalagin against Vibrio parahaemolyticus
FoodsThis study sought to explore the antimicrobial activity of punicalagin against V. parahaemolyticus and its potential modes of action. V. parahaemolyticus ATCC 17802 and RIMD 2210633Sm were exposed to punicalagin, and the energy production, membrane ...
Hongli Liu +3 more
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Punicalagin Regulates Signaling Pathways in Inflammation-Associated Chronic Diseases [PDF]
Antioxidants, 2021 Inflammation is a complex biological defense system associated with a series of chronic diseases such as cancer, arthritis, diabetes, cardiovascular and neurodegenerative diseases.
Jie Xu +5 more
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Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach [PDF]
Fundamental ResearchThe formation of liquid condensates by nucleocapsid (N) protein and viral RNA is a critical and highly conserved event in the life cycle of numerous viruses. Targeting this process emerges as a possible strategy to combat viral infections.
Shao-Zhen Jiang +26 more
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Integrated Phenotypic and Transcriptomic Analyses Unveil the Antibacterial Mechanism of Punicalagin Against Methicillin-Resistant Staphylococcus aureus (MRSA) [PDF]
FoodsThe growing emergence of multidrug-resistant bacterial pathogens drives the need for new antibacterial agents. Punicalagin exhibits efficacy against methicillin-resistant Staphylococcus aureus (MRSA), but its specific antibacterial mechanisms remain ...
Yiming Wang +7 more
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Pharmacological Activities of Punicalagin: A Review
Journal of Drug Delivery and Therapeutics, 2022 Traditional medicine was becoming more popular as a component of complementary and alternative medicine around the world. The ability to provide information on the pharmacological effects of plants requires a thorough understanding of the chemical components found in plants.
Fitra Fauziah, Sri Oktavia, Novia Rozadi
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A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches [PDF]
Biomedicines, 2021 In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity.
Giuliano Paglia +7 more
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Pharmaceutical Biology, 2023 Context Punicalagin has myocardial protection; the mechanism of punicalagin on ventricular remodeling (VR) after acute myocardial infarction (AMI) remains unclear.Objective These studies explore the role and mechanism of punicalagin in preventing and ...
Jian-fei Peng +9 more
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Effect of punicalagin on proliferation of porcine ovarian granulosa cells in vitro [PDF]
Journal of Central European Agriculture, 2016 Punicalagin is a major component responsible for pomegranate's (Punica granatum) antioxidant properties. Punicalagin is the predominant ellagitannin of Punica granatum and present in two isomeric forms: punicalagin α and β.
Dagmara Packová, Adriana Kolesárová
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Acta Pharmaceutica, 2022 Allergic asthma is an inflammatory disease of the airways which has a complex etiology. Punicalagin, a major polyphenol present in pomegranates, is reported to possess various biological properties including antioxidant and antiproliferative effects. The
Yu Li, Li Jianying
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