Results 1 to 10 of about 3,384 (184)

Punicalagin suppresses methicillin resistance of Staphylococcus aureus to oxacillin

Journal of Pharmacological Sciences, 2018
Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that is cross-resistant to most β-lactam antibiotics. We investigated whether oxacillin, which is a β-lactam antibiotic, alone or in combination with punicalagin can affect
Su-Hyun Mun, Ok-Hwa Kang, Ryong Kong
exaly   +6 more sources

Physiological and Immune Functions of Punicalagin [PDF]

Nutrients, 2021
The aim of this publication is to compile a summary of the findings regarding punicalagin in various tissues described thus far in the literature, with an emphasis on the effect of this substance on immune reactions. Punicalagin (PUN) is an ellagitannin found in the peel of pomegranate (Punica granatum).
Adriana Kolesárová, Pavel Horky, Petr Slama   +2 more
exaly   +6 more sources

Punicalagin Targets Atherosclerosis: Gene Expression Profiling of THP-1 Macrophages Treated with Punicalagin and Molecular Docking

Current Issues in Molecular Biology, 2022
Atherosclerosis is an important cause of cardiovascular disorders worldwide. Natural botanical drugs have attracted attention due to their antioxidant, anti-inflammatory, and antiatherogenic properties in the treatment of atherosclerosis.
Etimad Huwait, Sanaa Almowallad, Rehab Al-Massabi, Salma Saddeek, Kalamegam Gauthaman, Alexandre Prola   +5 more
doaj   +4 more sources

Exploring Punicalagin Potential Against Cancers: A Comprehensive Review [PDF]

Food Science and Nutrition
ABSTRACTPunicalagin, being a bioactive polyphenol, has gained significant interest owing to its potential anticancer effects. Researchers are studying punicalagin to determine its ability to inhibit cancer cell proliferation. This paper focuses on highlighting the therapeutic potential of punicalagin against tumors and cancers.
Hammad Naeem, Waleed Al Abdulmonem, Tadesse Fenta Yehuala   +2 more
exaly   +4 more sources

Antibiofilm effects of punicalagin against Staphylococcus aureus in vitro

Frontiers in Microbiology, 2023
Staphylococcus aureus is a common foodborne pathogen which can form biofilms to help them resist to antimicrobials. It brings great harm to human health. Punicalagin has good antimicrobial activities against S. aureus, but its effect on biofilm formation
Yunfeng Xu, Weiping Guo, Denglin Luo, Peiyan Li, Jinle Xiang, Junliang Chen, Xiaodong Xia, Qinggang Xie   +7 more
doaj   +3 more sources

Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia [PDF]

PeerJ, 2021
Background Punicalagin is the major phenolic compound found in pomegranate peels. It has several reported medical benefits, including antioxidant, anti-inflammatory, and anticancer properties.
Paweena Subkorn, Chosita Norkaew, Kamolchanok Deesrisak, Dalina Tanyong   +3 more
doaj   +4 more sources

Punicalagin Inhibits the Growth and Proliferation of Ovarian Epithelial Adenocarcinoma Cells Via Apoptosis and Autophagic Cell Death. [PDF]

J Biochem Mol Toxicol
Punicalagin targets ovarian cancer via multiple anti‐cancer mechanisms. This graphical abstract summarizes the key findings of the study on the effects of Punicalagin (PCG), a pomegranate‐derived polyphenol, on ovarian cancer cells (OVCAR‐3 and SKOV‐3).
Bhutta ZA, Kim CW, Na H, Lee HK, Choi KC.   +4 more
europepmc   +2 more sources

Antibacterial and antiviral properties of punicalagin (Review). [PDF]

Med Int (Lond)
Punicalagin, a polyphenolic compound extracted from pomegranate peel, has received increasing attention in recent years due to its antibacterial and antiviral properties. Punicalagin is capable of inhibiting bacterial growth at sub-inhibitory concentrations by affecting cell membrane formation, disrupting membrane integrity, altering cell permeability,
Song Z, Wang Y, Zhang P, Wang Y, Li Y, Liu F, Long J, Yang H.   +7 more
europepmc   +4 more sources

A Systematic Study of the Hepatic–Intestinal First-Pass Effect and Excretion Pathways of Punicalagin Based on UPLC-MS/MS [PDF]

Molecules
Punicalagin, the major polyphenol in pomegranate peel, shows broad bioactivity but suffers from poor oral bioavailability. Whether hepatic or intestinal first-pass processes dominate this limitation remains unresolved. We developed a quantitative UPLC-MS/
Zixin Chen, Zhanying Chang, Pengxia Yao, Xiaoli Gao   +3 more
doaj   +2 more sources

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection [PDF]

Advanced Science
Mycobacterium abscessus (MAB) is an increasingly recognized rapidly growing nontuberculous mycobacterial pathogen whose infection is particularly challenging to treat due to its antibiotic resistance and persistence, necessitating the exploration of ...
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
doaj   +2 more sources