Results 21 to 30 of about 3,384 (184)
Molecules, 2023 This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate
Damarius S. Fleming +2 more
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Punicalagin Regulates Key Processes Associated with Atherosclerosis in THP-1 Cellular Model
Pharmaceuticals, 2020 Atherosclerosis may lead to cardiovascular diseases (CVD), which are the primary cause of death globally. In addition to conventional therapeutics for CVD, use of nutraceuticals that prevents cholesterol deposition, reduce existing plaques and hence anti-
Sanaa Almowallad +5 more
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Potential role of punicalagin against oxidative stress induced testicular damage
Asian Journal of Andrology, 2016 Punicalagin is isolated from pomegranate and widely used for the treatment of different diseases in Chinese traditional medicine. This study aimed to evaluate the effect of Punicalagin (purity ≥98%) on oxidative stress induced testicular damage and its ...
Faiza Rao +4 more
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Punicalagin Restricts Growth, Promotes Apoptosis, and Reduces Invasion in Human Gastric Cancer Cells
Dose-ResponseThis research investigated the anticancer properties of punicalagin, a prominent bioactive polyphenol extracted from Punica granatum L, in human gastric cancer cell lines. Normal and gastric cancer cells were exposed to different doses of punicalagin for
Ding-Ping Sun +6 more
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Bioactive potential of punicalagin: A comprehensive review
Applied Food ResearchPomegranates comprise bioactive components including polyphenols, tannins, and anthocyanins, which have demonstrated beneficial health effects. Pomegranates also act as a preventative measure for a variety of ailments, as per the promising results from ...
Irtiqa Shabir +10 more
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An in vitro antiviral evaluation of punicalagin toward influenza A virus
, 2022 Abstract Background: Influenza complications are mild to serious, and can cause death in some cases. A great deal of attention has been paid in recent years to the development and use of new antiviral compounds for drug resistance in certain strains of the influenza virus and the clinical implications.
Fatemeh Javadi-Farsani +4 more
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Antimicrobial and Immunomodulatory Effects of Punicalagin and Meropenem in a Murine Model of Sublethal Sepsis [PDF]
AntibioticsBackground: Punicalagin (Pg), a major ellagitannin derived from pomegranates, possesses antimicrobial, antioxidant, and immunomodulatory properties, suggesting its potential as an adjunctive therapy for sepsis.
Liliane dos Santos Rodrigues +7 more
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Analysis of Punicalin and Punicalagin Interaction with PDIA3 and PDIA1 [PDF]
International Journal of Molecular SciencesPDIA3 is a pleiotropic protein primarily located in the endoplasmic reticulum where it is involved in protein folding, catalyzing the formation, breakage, and rearrangement of disulfide bonds. PDIA3 is implicated in numerous pathologies such as cancer, inflammation, and neurodegeneration.
Meschiari, Giorgia +5 more
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BMC Complementary Medicine and TherapiesBackground Multidrug resistance (MDR) in the family Enterobacteriaceae is a perniciously increasing threat to global health security. The discovery of new antimicrobials having the reversing drug resistance potential may contribute to augment and revive ...
Saba Kiran +14 more
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Veterinary SciencesAfrican swine fever (ASF), caused by the African swine fever virus (ASFV), has resulted in significant losses in the global pig industry. Considering the absence of effective vaccines, developing drugs against ASFV may be a crucial strategy for its ...
Renhao Geng +10 more
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