Results 91 to 100 of about 3,384 (184)

Anti‐inflammatory effects of punicalagin on LPS‐activated microglia

The FASEB Journal, 2019
Pomegranate ( Punica granatum L.) is a popular fruit originated in the Middle East and has been widely planted around the world. It contains various phytochemicals such as polyphenolic compounds and has a wide range of biological activities, including anti‐inflammatory, anti‐tumor ...
Yueh‐Shan Lee, Yi‐Xin Lai, Chia‐Yang Li   +2 more
openaire   +1 more source

Punicalagin Protects Ram Sperm from Oxidative Stress by Enhancing Antioxidant Capacity and Mitochondrial Potential during Liquid Storage at 4 °C

Animals
The aim of this study was to investigate the effect of punicalagin, an antioxidant, on ram sperm quality. Semen samples were collected and pooled from five rams, then diluted using a Tris-based diluent containing various concentrations (0, 5, 15, 30 and ...
Liuming Zhang, Xuyang Wang, Tariq Sohail, Caiyu Jiang, Yuxuan Sun, Jian Wang, Xiaomei Sun, Yongjun Li   +7 more
doaj   +1 more source

Pomegranate Peel Extract Microemulsions for Skin Delivery: Insights into Drug Release, Skin Permeation and UV Protection

Cosmetics
Pomegranate peel, an abundant agro-industrial by-product, represents a sustainable source of bioactive polyphenols, particularly punicalagin, which has been associated with antioxidant and photoprotective potential.
Nataša Bubić Pajić, Teodora Trninić, Darija Knežević Ratković, Vesna Antunović, Katarina Šavikin, Jelena Živković, Ranko Škrbić   +6 more
doaj   +1 more source

Inhibition of telomerase activity and cell growth by free and nanoliposomal forms of punicalagin in human leukemia cell line K562

, 2016
Purpose: To prepare punicalagin-loaded nanoliposome and compare its anti-telomerase activity in K562 cell line with that of free punicalagin.Methods: Punicalagin-loaded nanoliposomes were prepared by extrusion method, and the efficiency of punicalagin ...
Faezizadeh, Zohreh, Gharib, Amir, Godarzee, Masoud   +2 more
core   +2 more sources

Computational investigations of potential inhibitors of monkeypox virus envelope protein E8 through molecular docking and molecular dynamics simulations

Scientific Reports
The World Health Organization (WHO) has declared the monkeypox outbreak a public health emergency, as there is no specific therapeutics for monkeypox virus (MPXV) disease. This study focused on docking various commercial drugs and plant-derived compounds
Rohit Das, Anil Bhattarai, Rohit Karn, Buddhiman Tamang   +3 more
doaj   +1 more source

Analysis of Osteosarcoma Cell Lines and Patient Tissue Using a 3D In Vivo Tumor Model—Possible Effects of Punicalagin

Organoids
Osteosarcomas are the most common primary malignant bone tumors and mostly affect children, adolescents, and young adults. Despite current treatment options such as surgery and polychemotherapy, the survival of patients with metastatic disease remains ...
Anna Rebecca Dorn, Sara Neff, Sophia Hupp, Melissa Engelhardt, Eric Pion, Ulrich Lenze, Carolin Knebel, Anna Duprée, Simone Schewe, Markus Weber, Christian Wulbrand, Axel Hillmann, Florian Weber, Phillip Clarke, Philipp Kainz, Thiha Aung, Silke Haerteis   +16 more
doaj   +1 more source

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

Journal of Inflammation Research, 2022
Jung Lo,1,2 Ching-Chih Liu,3,4 Yueh-Shan Li,3 Po-Yen Lee,3,5 Po-Len Liu,6 Pei-Chang Wu,1,2 Tzu-Chieh Lin,7 Chi-Shuo Chen,8 Chien-Chih Chiu,9 Yu-Hung Lai,3,5,10 Yo-Chen Chang,3,5,10 Hsin-En Wu,3 Yuan-Ru Chen,3 Yu-Kai Huang,3,11 Shu-Pin Huang,1,12– 14 Shu ...
Lo J, Liu CC, Li YS, Lee PY, Liu PL, Wu PC, Lin TC, Chen CS, Chiu CC, Lai YH, Chang YC, Wu HE, Chen YR, Huang YK, Huang SP, Wang SC, Li CY   +16 more
doaj  

Anti-inflammatory effects of phenolic acids punicalagin and curcumin in human placenta and adipose tissue

, 2022
Introduction: The world is witnessing a steady rise in the prevalence of gestational diabetes mellitus (GDM), correlated with the current obesity epidemic.
C Nguyen-Ngo (13347576), Jane Willcox (13077636), M Lappas (13347564)   +2 more
core  

Anticancer effects of Punicalagin

Haydarpasa Numune Training and Research Hospital Medical Journal, 2021
openaire   +1 more source

Punicalagin increases glutamate absorption in differentiated Caco-2 cells by a mechanism involving gene expression regulation of an EAAT3 transporter

, 2019
This study investigates, for the first time, the ability of punicalagin to modulate intestinal glutamate uptake by upregulation of the expression of one of its transporters present on the enterocyte membrane.
Jud C., Bee G., Biolley C., Tretola M., Silacci P.   +4 more
core   +1 more source