Results 11 to 20 of about 3,654 (184)

Punicalagin suppresses methicillin resistance of Staphylococcus aureus to oxacillin

open access: yesJournal of Pharmacological Sciences, 2018
Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen that is cross-resistant to most β-lactam antibiotics. We investigated whether oxacillin, which is a β-lactam antibiotic, alone or in combination with punicalagin can affect
Ok-Hwa Kang   +2 more
exaly   +6 more sources

Punicalagin Targets Atherosclerosis: Gene Expression Profiling of THP-1 Macrophages Treated with Punicalagin and Molecular Docking

open access: yesCurrent Issues in Molecular Biology, 2022
Atherosclerosis is an important cause of cardiovascular disorders worldwide. Natural botanical drugs have attracted attention due to their antioxidant, anti-inflammatory, and antiatherogenic properties in the treatment of atherosclerosis.
Etimad Huwait   +5 more
doaj   +4 more sources

Antifungal potential of punicalagin against Cryptococcus neoformans species complex [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2018
This study evaluated the antifungal activity and cytotoxicity profile of the ellagitannin punicalagin, a compound extracted from the L. pacari A. St.-Hil (Lythraceae) leaf, against Cryptococcus neoformans species complex.
Thaísa Cristina Silva   +9 more
doaj   +6 more sources

Antimicrobial Activity and Mechanisms of Punicalagin against Vibrio parahaemolyticus

open access: yesFoods
This study sought to explore the antimicrobial activity of punicalagin against V. parahaemolyticus and its potential modes of action. V. parahaemolyticus ATCC 17802 and RIMD 2210633Sm were exposed to punicalagin, and the energy production, membrane ...
Hongli Liu   +3 more
doaj   +4 more sources

Punicalagin Regulates Signaling Pathways in Inflammation-Associated Chronic Diseases [PDF]

open access: yesAntioxidants, 2021
Inflammation is a complex biological defense system associated with a series of chronic diseases such as cancer, arthritis, diabetes, cardiovascular and neurodegenerative diseases.
Jie Xu   +5 more
doaj   +4 more sources

Pharmacological Activities of Punicalagin: A Review [PDF]

open access: yesJournal of Drug Delivery and Therapeutics, 2022
Traditional medicine was becoming more popular as a component of complementary and alternative medicine around the world. The ability to provide information on the pharmacological effects of plants requires a thorough understanding of the chemical components found in plants.
Fitra Fauziah, Sri Oktavia, Novia Rozadi
openaire   +2 more sources

Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach [PDF]

open access: yesFundamental Research
The formation of liquid condensates by nucleocapsid (N) protein and viral RNA is a critical and highly conserved event in the life cycle of numerous viruses. Targeting this process emerges as a possible strategy to combat viral infections.
Shao-Zhen Jiang   +26 more
doaj   +3 more sources

A Comparative Analysis of Punicalagin Interaction with PDIA1 and PDIA3 by Biochemical and Computational Approaches [PDF]

open access: yesBiomedicines, 2021
In a previous work, it was shown that punicalagin, an active ingredient of pomegranate, is able to bind to PDIA3 and inhibit its disulfide reductase activity.
Giuliano Paglia   +7 more
doaj   +3 more sources

Punicalagin attenuates ventricular remodeling after acute myocardial infarction via regulating the NLRP3/caspase-1 pathway

open access: yesPharmaceutical Biology, 2023
Context Punicalagin has myocardial protection; the mechanism of punicalagin on ventricular remodeling (VR) after acute myocardial infarction (AMI) remains unclear.Objective These studies explore the role and mechanism of punicalagin in preventing and ...
Jian-fei Peng   +9 more
doaj   +2 more sources

Effect of punicalagin on proliferation of porcine ovarian granulosa cells in vitro [PDF]

open access: yesJournal of Central European Agriculture, 2016
Punicalagin is a major component responsible for pomegranate's (Punica granatum) antioxidant properties. Punicalagin is the predominant ellagitannin of Punica granatum and present in two isomeric forms: punicalagin α and β.
Dagmara Packová, Adriana Kolesárová
doaj   +3 more sources

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