Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways [PDF]
Acta Pharmaceutica, 2022 Allergic asthma is an inflammatory disease of the airways which has a complex etiology. Punicalagin, a major polyphenol present in pomegranates, is reported to possess various biological properties including antioxidant and antiproliferative effects. The
Yu Li, Li Jianying
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Punicalagin-enriched edible coatings from revalorized pomegranate peels for quality enhancement of fresh-cut celery. [PDF]
J Sci Food AgricAbstract BACKGROUND Pomegranate peel is a rich source of phenolics, particularly punicalagin, but its valorization for fresh produce preservation requires stabilization. This study aimed to develop and evaluate freeze‐dried encapsulates of pomegranate peel extracts as ingredients in edible coatings for fresh‐cut celery. Pomegranate peels were extracted
Martínez-Zamora L +3 more
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Antibiofilm effects of punicalagin against Staphylococcus aureus in vitro
Frontiers in Microbiology, 2023 Staphylococcus aureus is a common foodborne pathogen which can form biofilms to help them resist to antimicrobials. It brings great harm to human health. Punicalagin has good antimicrobial activities against S. aureus, but its effect on biofilm formation
Yunfeng Xu +7 more
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Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia [PDF]
PeerJ, 2021 Background Punicalagin is the major phenolic compound found in pomegranate peels. It has several reported medical benefits, including antioxidant, anti-inflammatory, and anticancer properties.
Paweena Subkorn +3 more
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Punicalagin promotes human villous trophoblast differentiation
Placenta, 2016 Poor differentiation of trophoblasts is associated with placental dysfunction, predisposing women to multiple pregnancy disorders. Punicalagin, a prominent ellagitannin in pomegranate juice has been shown to exert anti-apoptosis and anti-oxidative effects in human trophoblasts. We hypothesized that punicalagin modulates trophoblast differentiation.
Baosheng, Chen +3 more
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The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum). [PDF]
Phytother ResThe Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Maiuolo J +11 more
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Punicalagin Inhibits the Growth and Proliferation of Ovarian Epithelial Adenocarcinoma Cells Via Apoptosis and Autophagic Cell Death. [PDF]
J Biochem Mol ToxicolPunicalagin targets ovarian cancer via multiple anti‐cancer mechanisms. This graphical abstract summarizes the key findings of the study on the effects of Punicalagin (PCG), a pomegranate‐derived polyphenol, on ovarian cancer cells (OVCAR‐3 and SKOV‐3).
Bhutta ZA +4 more
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Punicalagin Regulates Key Processes Associated with Atherosclerosis in THP-1 Cellular Model
Pharmaceuticals, 2020 Atherosclerosis may lead to cardiovascular diseases (CVD), which are the primary cause of death globally. In addition to conventional therapeutics for CVD, use of nutraceuticals that prevents cholesterol deposition, reduce existing plaques and hence anti-
Sanaa Almowallad +5 more
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Molecules, 2023 This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate
Damarius S. Fleming +2 more
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Potential role of punicalagin against oxidative stress induced testicular damage
Asian Journal of Andrology, 2016 Punicalagin is isolated from pomegranate and widely used for the treatment of different diseases in Chinese traditional medicine. This study aimed to evaluate the effect of Punicalagin (purity ≥98%) on oxidative stress induced testicular damage and its ...
Faiza Rao +4 more
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