Results 21 to 30 of about 5,242 (212)

Antioxidant Activity and Potential Cholesterol Modulating Effect of Punica granatum L. Peel Hydroethanolic Extract. [PDF]

Chem Biodivers
Punica granatum peel extract is rich in phenolic compounds, exhibits strong antioxidant activity, and modulates the expression of PCSK9 and LDL receptors. Collectively, these findings suggest a potential cardioprotective effect of the extract. ABSTRACT Lipoprotein metabolism is regulated by several key proteins, notably proprotein convertase subtilisin/
Chaaba R, Nakbi A, Rossi I, Jrah H, Amri Z, Ferri N, Hammami S, Dall'Acqua S, Hammami M, Mehri S.   +9 more
europepmc   +2 more sources

Effect of punicalagin on proliferation of porcine ovarian granulosa cells in vitro [PDF]

Journal of Central European Agriculture, 2016
Punicalagin is a major component responsible for pomegranate's (Punica granatum) antioxidant properties. Punicalagin is the predominant ellagitannin of Punica granatum and present in two isomeric forms: punicalagin α and β.
Dagmara Packová, Adriana Kolesárová
doaj   +1 more source

Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways

Acta Pharmaceutica, 2022
Allergic asthma is an inflammatory disease of the airways which has a complex etiology. Punicalagin, a major polyphenol present in pomegranates, is reported to possess various biological properties including antioxidant and antiproliferative effects. The
Yu Li, Li Jianying
doaj   +1 more source

Exploring Punicalagin Potential Against Cancers: A Comprehensive Review. [PDF]

Food Sci Nutr
ABSTRACTPunicalagin, being a bioactive polyphenol, has gained significant interest owing to its potential anticancer effects. Researchers are studying punicalagin to determine its ability to inhibit cancer cell proliferation. This paper focuses on highlighting the therapeutic potential of punicalagin against tumors and cancers.
Hassan MHU, Shahbaz M, Momal U, Naeem H, Imran M, Abdelgawad MA, Ghoneim MM, Mostafa EM, El-Ghorab AH, Alsagaby SA, Al Abdulmonem W, Hussain M, Yehuala TF.   +12 more
europepmc   +3 more sources

Punicalagin Ameliorates Lupus Nephritis via Inhibition of PAR2 [PDF]

International Journal of Molecular Sciences, 2020
Lupus nephritis (LN) is the most frequent phenotype in patients with systemic lupus erythematosus (SLE) and has a high rate of progression to end-stage renal disease, in spite of intensive treatment and maintenance therapies. Recent evidence suggests that protease-activated receptor-2 (PAR2) is a therapeutic target for glomerulonephritis. In this study,
Yohan Seo, Chin Hee Mun, So-Hyeon Park, Dongkyu Jeon, Su Jeong Kim, Taejun Yoon, Eunhee Ko, Sungwoo Jo, Yong-Beom Park, Wan Namkung, Sang-Won Lee   +10 more
openaire   +3 more sources

The polyphenolic compound punicalagin protects skin fibroblasts from UVA radiation oxidative damage

Current Research in Pharmacology and Drug Discovery
Polyphenols are a class of natural compounds that act as antioxidants, neutralising harmful free radicals that would damage cells and increase the risk of diseases such as cancer, diabetes and heart disease.
Giada Bianchetti, Patrizia Bottoni, Giuseppe Tringali, Giuseppe Maulucci, Elisabetta Tabolacci, Maria Elisabetta Clementi   +5 more
doaj   +5 more sources

Pharmacological Activities of Punicalagin: A Review

Journal of Drug Delivery and Therapeutics, 2022
Traditional medicine was becoming more popular as a component of complementary and alternative medicine around the world. The ability to provide information on the pharmacological effects of plants requires a thorough understanding of the chemical components found in plants.
Fitra Fauziah, Sri Oktavia, Novia Rozadi
openaire   +1 more source

Differential Correlation of Transcriptome Data Reveals Gene Pairs and Pathways Involved in Treatment of Citrobacter rodentium Infection with Bioactive Punicalagin

Molecules, 2023
This study is part of the work investigating bioactive fruit enzymes as sustainable alternatives to parasite anthelmintics that can help reverse the trend of lost efficacy. The study looked to define biological and molecular interactions that demonstrate
Damarius S. Fleming, Fang Liu, Robert W. Li   +2 more
doaj   +1 more source

Quantification of punicalagin in pomegranate peels from high-performance thin-layer chromatography

Biomedical and Biotechnology Research Journal, 2022
Background: Punicalagin is the main phenolic compound present in pomegranate (Punica granatum), it possesses various kinds of activities which is very essential as a dietary supplement, herbal supplements, or nutraceuticals are widely available in the ...
Pooja Gadkari, Sanjay J Daharwal
doaj   +1 more source

Punicalagin Damages the Membrane of Salmonella Typhimurium

Journal of Food Protection, 2020
Salmonella, a bacterial foodborne pathogen, can contaminate meat, milk, and vegetables. While appropriate measures are available to control Salmonella, the inhibitory phytochemicals from plants are gaining increased attention. Punicalagin, a natural antimicrobial, is one of the main active tannins isolated from Punica granatum L.
Guanghui Li, Yunfeng Xu, Liang Pan, Xiaodong Xia   +3 more
openaire   +2 more sources