Results 61 to 70 of about 5,242 (212)

Punicalagin Inhibits Salmonella Virulence Factors and Has Anti-Quorum-Sensing Potential [PDF]

Applied and Environmental Microbiology, 2014
ABSTRACT Punicalagin, an essential component of pomegranate rind, has been demonstrated to possess antimicrobial activity against several food-borne pathogens, but its activity on the virulence of pathogens and its anti-quorum-sensing (anti-QS) potential have been rarely reported.
Guanghui, Li, Chunhong, Yan, Yunfeng, Xu, Yuqing, Feng, Qian, Wu, Xiaoying, Lv, Baowei, Yang, Xin, Wang, Xiaodong, Xia   +8 more
openaire   +2 more sources

Effects of olive and pomegranate by-products on human microbiota : a study using the SHIME (R) in vitro simulator [PDF]

, 2019
Two by-products containing phenols and polysaccharides, a "pate" (OP) from the extra virgin olive oil milling process and a decoction of pomegranate mesocarp (PM), were investigated for their effects on human microbiota using the SHIME (R) system.
Daghio, Matteo, Franzetti, Andrea, Giuliani, Camilla, Innocenti, Marzia, Marzorati, Massimo, Mulinacci, Nadia, Van de Wiele, Tom   +6 more
core   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Punicalagin and Ketogenic Amino Acids Loaded Organic Lipid Carriers Enhance the Bioavailability, Mitochondrial β-Oxidation, and Ketogenesis in Maturing Adipocytes

Nanomaterials, 2022
The identification of lipolytic bioactive compounds via the functional stimulation of carbohydrate response element-binding protein-1 (CREBp-1) and AMP-activated protein kinase (AMPK) is most warranted.
Pandurangan Subash-Babu, Nouf Al-Numair, Tahani Almuzaini, Jegan Athinarayanan, Ali Abdullah Alshatwi   +4 more
doaj   +1 more source

In vitro permeation and biological activity of punicalagin and zinc (II) across skin and mucous membranes prone to Herpes simplex virus infection [PDF]

, 2017
Coadministration of pomegranate rind extract (PRE) and zinc (II) ions has recently been reported as a potential new topical treatment for Herpes simplex virus (HSV) infections. In the current work we examined the in vitro topical delivery of punicalagin (
Bugert, Joachim J., Denyer, Stephen P., Heard, Charles M., Houston, David M. J., Robins, Bethan   +4 more
core   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Transcriptomic analysis of Bursaphelenchus xylophilus treated by a potential phytonematicide, punicalagin [PDF]

Journal of Nematology, 2020
Abstract Punicalagin showed significant nematotoxic activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, in the authors’ previous research. The authors performed high-throughput transcriptomic sequencing of punicalagin-treated nematodes to generate clues for its nematotoxic mechanism of action.
Guo, Qun-Qun, Du, Gui-Cai, Zhang, Ting-Ting, Wang, Mei-Juan, Wang, Chao, Qi, Hong-Tao, Li, Rong-Gui   +6 more
openaire   +3 more sources

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Phytochemicals from Algerian medicinal plants were virtually screened as potential phosphodiesterase‐5 (PDE5) inhibitors for erectile dysfunction therapy. Drug‐likeness and toxicity analyses identified catechin, ellagic acid, and rosmarinic acid as safe, bioavailable candidates.
Farouk Boudou, Alaeddine Berkane, Amal Belakredar, Ahcene Keziz, Huda Alsaeedi, Brian A. Murray, Mikhael Bechelany, Ahmed Barhoum   +7 more
wiley   +1 more source

Optimization of Processing Parameters and Quality Evaluation of Breakfast Flakes Prepared From Sonicated Corn and Its By‐Products Supplemented With Quinoa Powder

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Optimization of processing parameters and quality evaluation of breakfast flakes prepared from sonicated corn, and its by‐products supplemented with quinoa powder. ABSTRACT Corn cob (C) and silk (S), produced in substantial quantities as agro‐waste, are rich in bioactive compounds with disease‐preventive potential.
Hina Niaz, Amna Javed, Rida Niaz
wiley   +1 more source

Aqueous extract of pomegranate peels (Punica granatum) encapsulated by spray drying. [PDF]

, 2017
Tannins, as punicalagin, represent the predominant class of bioactive substances from pomegranate, concentrating mostly in the peels and fruit mesocarp.
CARLOS, A. L. M., FREITAS, S. C. de, GODOY, R. L. de O., NOGUEIRA, R. I., PAIM, D. R. S. F., SANTIAGO, M. C. P. de A., SANTOS, L. F., WILBERG, V. C.   +7 more
core