Results 51 to 60 of about 67,313 (262)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Jurnal PerformaAbstrak: Penelitian ini dilakukan dengan TikTok app sebagai objek penelitian. Penelitian ini bertujuan untuk mengetahui pengaruh Live Commerce dan Social Media Advertising terhadap Purchase Intention dengan variabel Impulse Buying Behavior yang ...
Wilbert Suwignyo +1 more
doaj +1 more source
The effect of individual factors of consumers on their buying behavior in social commerce sites with the moderating role of privacy concerns [PDF]
کاوشهای مدیریت بازرگانیEXTENDED ABSTRACTIntroductionThe rapid proliferation of the internet has significantly reshaped the retail industry, driving a fundamental shift in consumer behavior towards e-commerce.
Samad Rahimiaghdam +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Exploring the moderation effect of consumers’ demography in the online purchase behavior
Cogent Business & ManagementResearch findings on the relationship between online purchase intention and actual purchase show inconsistencies, suggesting that intention alone does not adequately predict online purchasing behavior.
Ni Luh Putu Indiani +2 more
doaj +1 more source
The influence of ecological concern on green purchase behavior
Management şi Marketing, 2021 The present paper seeks to address a gap in the literature regarding green marketing and examines the relationship between ecological concern, inward and outward environmental attitudes, purchasing behavior and environmental behavior as antecedents of ...
Fontes Eva +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source