Results 71 to 80 of about 67,313 (262)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

What influences consumers’ online medication purchase intentions and behavior? A scoping review

Frontiers in Pharmacology
Objective: Consumers increasingly buy pharmaceuticals online. No scoping review has been carried out to summarize and synthesize the studies that have identified drivers of consumers’ purchase intention and behavior from online pharmacies.
Yam B. Limbu, Bruce A. Huhmann
doaj   +1 more source

Behavioral Economics of Multiperiod Insurance Purchasing Behavior

Foundations and Trends® in Microeconomics, 2018
Consumers face many risky situations that can severely impact their wealth or health from one year to the next. People sometimes behave in inconsistent ways in such settings; many individuals faced with these risks do not consider purchasing insurance until after suffering a loss, but then they may cancel their policy a few years later if they have not
Howard Kunreuther, Mark Pauly
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The greenwashing trap: how misleading marketing affects consumer green purchasing habits

Business: Theory and Practice
The rising environmental concern has driven organizations to adopt green marketing practices. However, a growing number of organizations have been engaging in greenwashing practices, which mislead customers about their environmental performance.
Neringa Vilkaitė-Vaitonė
doaj   +1 more source

The Impact of Augmented Reality Attributes on Purchase Intentions: The Moderating Role of Brand Familiarity Among Generation Z. [PDF]

Mağallaẗ Rāyaẗ Al-Dawliyyaẗ Lil ʿulūm Al-Tiğāriyyaẗ
This research aimed to examine the influence of Augmented Reality (AR) Attributes on Purchase Intentions (PIs) and the moderating effect of Brand Familiarity (BF) within Generation Z.The research analyzed the concepts and dimensions of AR Attributes ...
Prof. Wageeh A. Nafei, Dr. Mohamed A. Abdel Razek, Khloud Ahmed Abdelsalam Khalifa   +2 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Buying the Forthcoming: The Effect of Value Congruence on Consumer Pre-Order Decisions

Journal of Theoretical and Applied Electronic Commerce Research
This study identifies the psychological factors that influence consumers’ pre-order decisions and the underlying mechanism. Building on the literature on value congruence in consumer behavior and cognitive consistency theory, we examine how value ...
Jung Hwan Kim, Soyoung Kim
doaj   +1 more source

Purchase and Post-Purchase Intentions of Ethical Consumer Behavior

, 2013
Two main streams of ethical consumer behavior are ethical consumerism and consumer ethics. While ethical consumerism is defined as consumers' decisions and behaviors to satisfy personal needs considering the results of their decisions with regard to environment and society (Ozkan, 2009), consumer ethics focuses on consumers' rightness of certain ...
Su Yun Bae, Ruoh-Nah (Terry) Yan
openaire   +2 more sources