Results 91 to 100 of about 24,465 (266)
Life, 2021 Phosphoserine phosphatase (PSP) catalyzes the final step of de novo L-serine biosynthesis—the hydrolysis of phosphoserine to serine and inorganic phosphate—in humans, bacteria, and plants.
Francesco Marchesani +5 more
doaj +1 more source
Purine-metabolising enzymes and apoptosis in cancer [PDF]
, 2019 The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation.
Allegrini S. +4 more
core +1 more source
Purine nucleoside phosphorylase in chronic lymphocytic leukemia (CLL) [PDF]
Blood, 1978 Purine nucleoside phosphorylase (PNP), the enzyme schematically next to adenosine deaminase in the purine salvage pathway, has been demonstrated cytochemically in peripheral blood lymphocytes of healthy subjects and chronic lymphocytic leukemia (CLL) patients. The enzyme activity is confined to the cytosol.
J. De Cree +6 more
openaire +4 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2015 Significance Enzyme catalytic cycles involve conformational changes that limit the usual steady-state catalytic rate to millisecond turnover numbers. Covalent bond changes occur at transition states with femtosecond lifetimes, a factor of 1012 faster ...
Javier Suárez, V. Schramm
semanticscholar +1 more source
Journal of the World Aquaculture Society, Volume 56, Issue 2, April 2025.Abstract Metabolism plays a crucial role in the growth rate of species. Proteomics serves as a potent tool to explore these metabolic changes. Herein, we investigated the metabolic growth differences in Gymnocypris przewalskii (GP) and Gymnocypris ecklon (GE). After 9 months of culture, the growth rate of GP was slower than that of GE (p < 0.05), while
Junming Zhou, Yun Zhao
wiley +1 more source
FEBS Open Bio, 2015 Mycoplasmas may colonize tumor tissue in patients. The cytostatic activity of gemcitabine was dramatically decreased inMycoplasma hyorhinis‐infected tumor cell cultures compared with non‐infected tumor cell cultures.
Johan Vande Voorde +3 more
doaj +1 more source
Circulating Human Neonatal Naïve B cells are Deficient in CD73 Impairing Purine Salvage
Frontiers in Immunology, 2016 Background: Extracellular purines, in particular adenosine (Ado) and adenosine-triphosphate (ATP), are critical immunoregulatory molecules. Expression and activity of purine ecto-enzymes on B cells in neonatal and adult blood may influence their function
Matthew Aaron Pettengill +2 more
doaj +1 more source
Polymorphisme de la purine nucléoside phosphorylase érythrocytaire bovine [PDF]
, 1984 La distribution de variants électrophorétiques de la purine nucléoside phosphorylase (N.P.) contrôlée par deux allèles NP.H et NP.L a été étudiée sur des hémolysats bovins appartenant à des populations autochtones de zébus ou de taurins (race Baoulé) et ...
Bambara, L., Quéval, Rémy
core
A UV/Vis Spectroscopy-Based Assay for Monitoring of Transformations Between Nucleosides and Nucleobases [PDF]
, 2019 Efficient reaction monitoring is crucial for data acquisition in kinetic and mechanistic studies. However, for conversions of nucleosides to their corresponding nucleobases, as observed in enzymatically catalyzed nucleoside phosphorylation reactions, the
Giessmann, Robert T. +5 more
core +1 more source
Purine Nucleoside Phosphorylase: Allosteric Regulation of a Dissociating Enzyme
Journal of Biological Chemistry, 1991 Purine nucleoside phosphorylase (EC 2.4.2.1) from bovine spleen is a trimeric enzyme that readily dissociates to the monomer. Dilution of enzyme from 20 to 0.02 microgram of protein/ml is accompanied by a greater than 50-fold increase in the specific activity (vtrimer = 0.23 nmol/min/microgram; vmonomer = 12.5 nmol/min/micrograms).
T W, Traut, P A, Ropp, A, Poma
openaire +5 more sources