Results 121 to 130 of about 151,646 (288)
iMeta, EarlyView.The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang +13 more
wiley +1 more source
Citation: 'purine' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09717 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
<b>Disruptions in Purine Metabolism: From Gout to Other Organ Systems.</b>
, 2016 Edward W. Holmes
openalex +2 more sources
iNew Medicine, EarlyView.Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang +9 more
wiley +1 more source
CONVERSION OF IMIDAZO[1,2-a]PYRIDINES INTO PYRIDO[1,2-e]PURINES [PDF]
, 1996 Alain Gueiffier +6 more
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Retraction of “Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies” [PDF]
, 2023 Vijay Shahani +9 more
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Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue
iNew Medicine, EarlyView.ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao +3 more
wiley +1 more source
Development of an Improved Assay for Purine Nucleoside Kinase Activity in Cell Extracts and Detection of Inosine Kinase Activity inBrevibacterium acetylicumATCC 953, Related Species, andCorynebacterium flaccumfaciensATCC 6887 [PDF]
, 2000 Hisashi Kawasaki +3 more
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Journal of Clinical Laboratory Analysis, EarlyView.We profiled tumors from 10 ovarian cancer patients with whole‐exome sequencing (WES), bulk RNA‐seq, and single‐cell RNA‐seq to uncover predictors of successful tumor‐infiltrating lymphocyte (TIL) isolation and expansion. TIL+ tumors exhibited enriched CD8+ Teff/Tem populations with distinctive metabolic activity, dendritic‐cell–skewed myeloid states ...
Xiuzhen Wang +7 more
wiley +1 more source