Results 141 to 150 of about 209,598 (340)

Purine Metabolism in Human and Chicken Blood, in Vitro

, 1960
Charles W. Bishop
openalex   +1 more source

CONVERSION OF IMIDAZO[1,2-a]PYRIDINES INTO PYRIDO[1,2-e]PURINES [PDF]

, 1996
Alain Gueiffier, Olivier Chavignon, Sylvie Mavel, Jean‐Michel Chezal, Jean‐Claude Teulade, Yves Blache, Jean‐Pierre Chapat   +6 more
openalex   +1 more source

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

Science, 2016
I. Ben-Sahra, G. Hoxhaj, S. Ricoult, J. Asara, B. Manning   +4 more
semanticscholar   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Effects of Low Temperature–Ultrasound–Papain (LTUP) Combined Treatments on Purine Removal from Pork Loin and Its Influence on Meat Quality and Nutritional Value

Foods
A combined pretreatment method of “low temperature-ultrasound-papain” (LTUP) was proposed to remove the purine of pork loins. Compared with untreated pork loin, under optimal conditions (temperature 58 °C, ultrasound density 100 W/cm2, and papain ...
Jiaojiao Yuan, Cheng Yang, Jialing Cao, Lianfu Zhang   +3 more
doaj   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Targeting de novo purine biosynthesis for tuberculosis treatment [PDF]

Dirk A. Lamprecht, Richard J. Wall, Alexander Leemans, Barry Truebody, Joke Sprangers, Patricia Fiogbe, Cadi Davies, J. Denise Wetzel, Stijn Daems, William H. Pearson, V.L. Pillay, Samantha Saylock, M. Daniel Ricketts, Ellie Davis, Adam Huff, Tsehai A.J. Grell, Shi‐Ming Lin, Michelle Gerber, Ann Vos, John Dallow, Sam Willcocks, Jacques Peretti, Stéphanie Sans, Amandine Desorme, Nicolas Chappat, Aurélie Ray, Mariana Pereira Moraes, Tracy Washington, Hope D’Erasmo, Pavankumar Sancheti, Melissa Everaerts, Mario Monshouwer, Jorge Esquivias, Gerald Larrouy‐Maumus, Ruxandra Draghia‐Akli, Helen A. Fletcher, Alexander S. Pym, Bree B. Aldridge, Jansy P. Sarathy, Kathleen Clancy, Bart Stoops, Neeraj Dhar, Adrie J. C. Steyn, Paul Jackson, Clara Aguilar-Pérez, Anil Koul   +45 more
openalex   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Correction: Application of Crystallographic and Modeling Methods in the Design of Purine Nucleoside Phosphorylase Inhibitors [PDF]

, 1992
S. E. Ealick
openalex   +1 more source