Results 151 to 160 of about 151,646 (288)

GameXPeptide synergistically enhances the control efficiency of Metarhizium anisopliae by inhibiting cotton aphid immunity

New Plant Protection, EarlyView.
In this research, GXP serves as a potent synergist for Metarhizium anisopliae in controlling cotton aphids. Its synergistic effect is achieved through two key mechanisms: first, by downregulating melanization protease 1 expression to inhibit phenoloxidase activity, thereby suppressing melanization; second, by reducing hypoxanthine levels, which ...
Xianfeng Yin, Xin Sun, Fenglian Jia, Shiqian Feng, Rong Zhang, Hidayat Ullah, Fulian Wang, Guangyue Li, Xiongbing Tu   +8 more
wiley   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

Purine and pyrimidine metabolism in lymphoid cells of man and some other mammalian species

, 1982
Godefridus J. Peters
openalex   +1 more source

A possible role for 5-phosphoribosyl 1-pyrophosphate in the stimulation of uterine purine nucleotide synthesis in response to oestradiol-17β

, 1972
Janet M. Oliver
openalex   +2 more sources

Morphine enhances purine nucleotide catabolism in vivo and in vitro [PDF]

, 2007
Chang Liu, Jiankai Liu, Mujie Kan, Lin Gao, Haiying Fu, Hang Zhou, Min Hong   +6 more
openalex   +1 more source

Pyrimidine-containing natural products: occurrences and biological activities. [PDF]

Nat Prod Bioprospect
Yao JN, Zhu Y, Chen HP, Chen Y.
europepmc   +1 more source

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management

ChemistryOpen, EarlyView.
Teucrium polium shows antidiabetic activity with its phytochemical composition and biological activities. The essential oil is rich in carvacrol, thymol, γ‐terpinene, and o‐cymene, while the aqueous and hydroethanolic extracts are characterized by poliumoside, verbascoside, isorhamnetin‐3‐O‐rutinoside, and apigenin‐7‐rutinoside. Antioxidant activity is
Hajar El Ouadni, Aziz Drioiche, Fadoua El Makhoukhi, Omkulthom Al kamaly, Hannou Zerkani, Smail Amalich, Imane Tagnaout, Mohamed Radi, Yahya Cherrah, Touriya Zair, Katim Alaoui   +10 more
wiley   +1 more source

Trans-Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids. [PDF]

MedComm (2020)
Ni Z, Cao C, Tian Y, Mu J, Tian H, Wang Z, Zhang S, Cao M, Yang Y, Lim WLF, Cui J, Sun H, Miao H, Wang Y, Du J, Kwok T, Chen H, Lam SM, Shui G.   +18 more
europepmc   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Antirhinovirus activity of purine nucleoside analogs

, 1986
Erik De Clercq, R Bernaerts, D. E. BERGSTROM, M. J. ROBINS, John A. Montgomery, Antonı́n Holý   +5 more
openalex   +2 more sources