Results 161 to 170 of about 187,335 (337)
Multi‐omics analysis of gut‐organ axes reveals the high‐altitude adaptation in Tibetan chicken
The Qinghai‐Tibet Plateau is an extreme ecosystem subject to special climatic conditions that require unique adaptations for its inhabiting organisms. In addition to genetic characteristics, the gut microbiota of animals can regulate the environmental adaptation of their hosts through various gut–organ axes.
Tao Zeng+15 more
wiley +1 more source
MXenes‐based flexible electronics for wound monitoring and treatment
This article provides a comprehensive overview of recent advancements in MXenes‐based flexible electronic devices for wound monitoring. It discusses the monitoring mechanisms and values for various wound pathological parameters as well as their applications in treating bacterial infections and chronic wounds.
Ye Yang+6 more
wiley +1 more source
New insights into applications of base editor in hereditary disorders
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai+8 more
wiley +1 more source
Abstract Objectives Pediatric acute pancreatitis (AP) is associated with gut dysbiosis. We aimed to determine if dysbiosis persisted during follow‐up and whether it is associated with clinical outcomes. Methods Prospective enrollment of participants <21 years with first AP.
Chinenye R. Dike+12 more
wiley +1 more source
The main processes involved in predicting the pre–osteoblast proliferation rate using Raman spectroscopy and machine learning. ABSTRACT This novel study focuses on using Raman spectroscopy and machine learning (ML) models to forecast the murine pre‐osteoblast (OB) proliferation rate.
Sai S. Sudha+3 more
wiley +1 more source
A New View into the Regulation of Purine Metabolism: The Purinosome.
Anthony M. Pedley, S. Benkovic
semanticscholar +1 more source
From molecule to medicine: introducing emerging strategies to synthesize potent anticancer purine scaffolds. [PDF]
Hashmi MA+4 more
europepmc +1 more source
Incorporation in vitro of Purine Ribosides into Deoxyribonucleic Acids of Ehrlich's Ascites Tumor Cells. [PDF]
Hans Klenow, Eleanor Lichtler
openalex +1 more source
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik+6 more
wiley +1 more source