Results 181 to 190 of about 311,690 (329)

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle

open access: yesCell, 2020
M. Z. Cader   +21 more
semanticscholar   +1 more source

Design, Optimized Synthesis, and Coordination Behavior of Quinolinic Benzimidazoles with Cu(II) and Ni(II): Reactivity Toward ROS, Computational Studies, and Biological Profiling

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
Synthesis and characterization of quinolinic benzimidazole Cu(II) and Ni(II) complexes reveal contrasting reactive oxygen species interactions and selective anticancer activity, highlighting a prodrug‐like mechanism. This study provides new insights into designing redox‐active metal complexes for targeted cancer therapeutics Benzimidazole is a well ...
Lorenzo Verderi   +3 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

A New View into the Regulation of Purine Metabolism: The Purinosome.

open access: yesTIBS -Trends in Biochemical Sciences. Regular ed, 2017
Anthony M. Pedley, S. Benkovic
semanticscholar   +1 more source

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

open access: yesFood Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang   +7 more
wiley   +1 more source

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