Results 181 to 190 of about 151,646 (288)

Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis

, 2020
Jiawei Wu, Zhonghong Wei, Peng Cheng, Cheng Qian, Fangming Xu, Yang Yu, Aiyun Wang, Wenxing Chen, Zhiguang Sun, Yin Lu   +9 more
openalex   +1 more source

Comprehensive metabolic profiling across five lifespan stages in murine hippocampus and cortex reveals sex-related variation in age-related cognitive decline. [PDF]

Commun Biol
Long X, Liu W, Chen C, Guo Q, Wang Y, Yu F, Zhang Y, Kellems RE, Xia Y.   +8 more
europepmc   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

Integrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu, Li Sun, Jiao Chen, Jing Wang, Miao Guan, Shixia Xu   +5 more
wiley   +1 more source

Purine [PDF]

, 2017
openaire   +2 more sources

Complex coordinated extracellular metabolism: Acid phosphatases activate diluted human leukocyte proteins to generate energy flow as NADPH from purine nucleotide ribose

, 2016
John B. Hibbs, Zdenek Vavrin, James E. Cox   +2 more
openalex   +1 more source

Disruption of purine <i>de novo</i> synthesis pathway impairs membrane homeostasis, intracellular survival, and virulence of <i>Brucella melitensis</i>. [PDF]

Front Microbiol
Yang G, Li M, Li Y, Chen S, Qu J, Li J, Wang S, Bao Y, Qi J, Dou Y, Tian M.   +10 more
europepmc   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

The inhibition of de novo purine synthesis increases LAMP2 expression to preserve cell viability. [PDF]

Cell Death Discov
De Cristofaro A, Castelli S, Felice F, Ciriolo MR, Desideri E.   +4 more
europepmc   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Interactions between serum uric acid and gut microbiota: implications for metabolic health. [PDF]

Metabol Open
Ali N.
europepmc   +1 more source