Results 181 to 190 of about 124,162 (316)

Hypothesis review: Alzheimer's overture guidelines

open access: yesBrain Pathology, Volume 33, Issue 1, January 2023., 2023
Brain aging with ADNC and sporadic Alzheimer's disease (sAD) form a prevalent continuum unique to humans. Molecular changes affecting cell membranes, cytoskeleton, synapses, lipid and protein metabolism, energy metabolism, neuroinflammation, cell cycle, astrocytes, microglia, and blood vessels precede and occur in parallel with early ADNC; and they are
Isidro Ferrer
wiley   +1 more source

THE PURINE METABOLISM OF ESCHERICHIA COLI

open access: hybrid, 1952
Arthur L. Koch   +2 more
openalex   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

open access: yesiMetaOmics, EarlyView.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang   +8 more
wiley   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

open access: yesiMeta, EarlyView.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang   +17 more
wiley   +1 more source

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