Results 191 to 200 of about 209,598 (340)

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Ameliorating Acute Kidney Injury Induced by Ischemia-Reperfusion by Targeting Purine Metabolism. [PDF]

Int J Mol Sci
Zhao L, Zhang T, Zhou X.
europepmc   +1 more source

Purin [PDF]

, 2019
openaire   +1 more source

A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice

Science Translational Medicine, 2017
Tyson R. Chiaro, R. Soto, W. Stephens, J. Kubinak, C. Petersen, Lasha Gogokhia, Rickesha S. Bell, Julio C. Delgado, Julio C. Delgado, James Cox, W. Voth, Jessica C. S. Brown, D. Stillman, Ryan M. O’Connell, A. Tebo, A. Tebo, J. Round   +16 more
semanticscholar   +1 more source

Bionic nanobombs target nasopharyngeal carcinoma to enhance the efficacy of chemoradiotherapy by destroying DNA damage repair systems

VIEW, EarlyView.
A bionic nanomedicine system with core–shell structure (Nm‐pAu/CP/KU) was constructed. PEGylated gold nanoparticles (pAu) were loaded with cisplatin (CP) and a radiochemotherapy sensitizer (KU‐60019) to form the core pAu/CP/KU, and homologous nasopharyngeal carcinoma cell membrane vesicles (Nm) were used as the shell.
Junhua Zhang, Xinying Xiang, Xinmin Nie, Jian Li, Rong Gui   +4 more
wiley   +1 more source

Comparative Binding Affinities of Platinum-Based Drugs toward Purine Alkaloids and Nucleobases. [PDF]

ACS Omega
Szefler B, Szupryczyński K.
europepmc   +1 more source

Supplementary Figure 3 from Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins

, 2023
Junkai Wang, Alexander B. Saltzman, Eric J. Jaehnig, Jonathan T. Lei, Anna Malovannaya, Matthew V. Holt, Meggie N. Young, Mothaffar F. Rimawi, Foluso O. Ademuyiwa, Meenakshi Anurag, Beom-Jun Kim, Matthew J. Ellis   +11 more
openalex   +1 more source

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

Nature Neuroscience, 2017
Xiuxing Wang, Kailin Yang, Qi Xie, Qiulian Wu, S. Mack, Yu Shi, Leo J. Y. Kim, B. Prager, William A. Flavahan, Xiaojing Liu, Meromit Singer, C. Hubert, Tyler E. Miller, Wenchao Zhou, Zhi Huang, X. Fang, A. Regev, M. Suvà, T. Hwang, J. Locasale, S. Bao, J. Rich   +21 more
semanticscholar   +1 more source

Congenital CMV Infection: Determination of Transplacental Passage of Aciclovir by Ex Vivo Placental Perfusion

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To quantify the transplacental transfer of aciclovir at an amount equivalent to 2 g of valaciclovir corresponding to the fractionated dosing regimen given four times daily used to reduce congenital cytomegalovirus (CMV) transmission and to treat the CMV‐infected fetus. Design Experimental ex vivo study.
Helyett Ollivier, Valentine Faure Bardon, Leo Froelicher Bournaud, Isidore Gaubert, Tiffany Guilleminot, Marianne Leruez‐Ville, Jean‐Marc Treluyer, Yves Ville, Gabrielle Lui, Julien Stirnemann   +9 more
wiley   +1 more source

Interventions for maintenance of surgically induced remission in Crohn's disease: a systematic review and network meta-analysis. [PDF]

BMJ Open Gastroenterol
Gordon M, Liu S, Sinopoulou V, Albuquerque DAN, Moran G.   +4 more
europepmc   +1 more source