Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients
ABSTRACT Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiology, clinically resembling pancreatic cancer, yet uniquely responsive to steroid treatment.
Vladyslav Dovhalyuk+5 more
wiley +1 more source
Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome. [PDF]
Tang JW, Tay ACY, Wang L.
europepmc +1 more source
Nucleotide‐bound crystal structures of the SARS‐CoV‐2 helicase NSP13
Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 capture a state immediately following ATP hydrolysis and reveal how crystal packing can affect structure‐based drug design targeting NSP13.Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 in ADP‐ and ATP‐bound states were resolved to 1.8 and 1.9 Å, respectively. The ADP‐bound model captures
Patrick Kloskowski+3 more
wiley +1 more source
Integrated multi-omics of feces, plasma and urine can describe and differentiate pediatric active Crohn's Disease from remission. [PDF]
Koopman N+15 more
europepmc +1 more source
Micro‐CT for the differentiation between live birth and stillbirth: A pilot study
Abstract The distinction between live births and stillbirths is crucial for determining the appropriate legal consequences. Historically, researchers have operated under the principle that an infant's lungs will be filled with air upon death, whereas a fetus's lungs will not.
Giovanni Botta+5 more
wiley +1 more source
We report the first high‐quality chromosome‐level genome assembly for the aphid Uroleucon formosanum, a serious pest that infests lettuce in eastern Asia. A combination of comparative genomic analyses and RNA‐seq transcriptome profiling suggests that U. formosanum employs integrative mechanisms to cope with host plant‐derived sesquiterpene lactone (STL)
Jing‐Bo Li+3 more
wiley +1 more source
Unraveling unbreakable hairpins: characterizing RNA secondary structures that are persistent after dinucleotide shuffling. [PDF]
Pratt AA, Hendrix DA.
europepmc +1 more source
GLYCINE AND ADENINE AS PRECURSORS OF NUCLEIC ACID PURINES IN TUMOR-BEARING MICE
Ralph K. Barclay, Esther Garfinkel
openalex +1 more source
Investigating soil mesofauna cryptic diversity: Current challenges and perspectives
Abstract Cryptic species lacking distinct morphological features are widespread among soil fauna, including such functionally significant groups as springtails, mites and enchytraeids. Their presence, diversity and biomass may impact ecosystem services provided by belowground ecosystems.
Margarita A. Danilova+3 more
wiley +1 more source
Whole-genome analysis of Bacillus paranthracis YC06 isolated from healthy individual feces for biodegrading inosine and guanosine. [PDF]
Cao X, Zhang Y, Xu Q, Yan H.
europepmc +1 more source