Results 201 to 210 of about 311,690 (329)

Synthesis and characterization of azanonaborane-containing purine derivatives for boron neutron capture therapy

Open Chemistry, 2008
Genady Afaf, El-Zaria Mohamed, Gabel Detlef   +2 more
doaj   +1 more source

Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress. [PDF]

Clin Cancer Res
Yu J, Jin C, Su C, Moon D, Sun MA, Zhang H, Jiang X, Zhang F, Tserentsoodol N, Bowie ML, Pirozzi CJ, George DJ, Wild R, Gao X, Ashley DM, He Y, Huang J.   +16 more
europepmc   +1 more source

Synthesis, spectral, antitumor and antimicrobial studies on Cu(II) complexes of purine and triazole Schiff base derivatives

, 2013
Said A. Amer, Nadia El‐Wakiel, Hoda A. El‐Ghamry   +2 more
openalex   +1 more source

Data from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB

, 2023
Ramakrishnan Gopalakrishnan, Hittu Matta, Preet M. Chaudhary   +2 more
openalex   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

Food Frontiers, EarlyView.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao, Huiying Liu, Peng Chen, Liyue Chen, Zhixin Chen, Jiaqiang Lin, Zixuan Fu, Zhipeng Li   +7 more
wiley   +1 more source

Cardiomyocyte-Specific Deletion of Sirtuin 5 Accelerates the Development of Heart Failure Upon Dysregulating Purine Metabolism. [PDF]

Acta Physiol (Oxf)
Byrne NJ, Koentges C, Pfeil K, Lueg JC, Bakshi S, Tarkhnishvili A, Vosko I, Gollmer J, Birkle LC, Rathner T, Birkle S, Tang S, Rau C, Hoffmann MM, Odening KE, Barnes S, Wilson LS, Ljubojevic-Holzer S, Wallner M, von Lewinski D, Rainer P, Sedej S, Sourij H, Bode C, Wende AR, Zirlik A, Bugger H.   +26 more
europepmc   +1 more source

High‐Dose Parenteral Iron Corrects Iron Deficiency Anemia While Disrupting Gut Microbiota and Metabolic Homeostasis in Neonatal Piglets

Food Frontiers, EarlyView.
Our results indicate that although high‐dose parenteral iron effectively corrects iron deficiency anemia (IDA), it causes liver dysfunction, immune suppression, systemic iron overload, and altered gut microbiota. ABSTRACT Iron deficiency anemia (IDA) is a common nutritional disorder in mammals, particularly affecting neonates and neonatal piglets ...
Qian Zhang, Yubin Hao, Xin Tian, Xuejiao Li, Jie Feng   +4 more
wiley   +1 more source

Purine metabolism: a pan-cancer metabolic dysregulation across circulation and tissues. [PDF]

Mol Cancer
Yu M, Liu C, Cao M, Yang D, Wang T, Xu J, Zhu D, Wang G, Aa J, Zhu W.   +9 more
europepmc   +1 more source

[[(Guaninylalkyl)phosphinico]methyl]phosphonic Acids. Multisubstrate Analog Inhibitors of Human Erythrocyte Purine Nucleoside Phosphorylase

, 1995
James L. Kelley, Ed W. McLean, Ronald C. Crouch, D R Averett, Joel V. Tuttle   +4 more
openalex   +1 more source

Wearable biosensors based on molecularly imprinted polymers

FlexMat, EarlyView.
Wearable biosensors based on molecularly imprinted polymers (MIPs) provide real‐time, non‐invasive monitoring of key biomarkers. This review highlights the research advances on MIPs‐based biosensors with enhanced selectivity, stability, and adaptability in flexible sensing platforms.
Xiangnan Li, Rongqi Ou, Zhen Yuan, Yuanjing Lin   +3 more
wiley   +1 more source