Emerging roles for integrated stress response signaling in homeostasis
Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar+2 more
wiley +1 more source
Synthesis of Purine-1,4,7,10-Tetraazacyclododecane Conjugate and Its Complexation Modes with Copper(II). [PDF]
Burcevs A+3 more
europepmc +1 more source
CAN PURINES, CREATININE, OR CREATINE REPLACE HISTIDINE IN THE DIET FOR PURPOSES OF GROWTH?
Gerald J. Cox, William C. Rose
openalex +1 more source
Yeast Culture Supplementation Improves Meat Quality by Enhancing Immune Response and Purine Metabolism of Small-Tail Han Sheep (<i>Ovis aries</i>). [PDF]
Bai X+11 more
europepmc +1 more source
PURINE-METABOLIZING ENZYMES OF TETRAHYMENA PYRIFORMIS
Herbert J. Eichel
openalex +1 more source
The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles
Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork+3 more
wiley +1 more source
3D-QSAR Design of New Bcr-Abl Inhibitors Based on Purine Scaffold and Cytotoxicity Studies on CML Cell Lines Sensitive and Resistant to Imatinib. [PDF]
Cabezas D+13 more
europepmc +1 more source
Hyperuricaemia in type 1 Gaucher disease: is uric acid a biomarker for disease severity?
Abstract Background Elevated serum uric acid (SUA) levels were observed in Gaucher disease type 1 (GD1) patients followed for two decades in northern Israel. There are no previous reports regarding hyperuricaemia in GD1 patients. Aims We aimed to evaluate the frequency of hyperuricaemia in GD1 patients and its correlation to disease severity ...
Zufit Hexner‐Erlichman+4 more
wiley +1 more source