Results 1 to 10 of about 31,971 (162)

Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia [PDF]

open access: yesPharmaceutics, 2022
We report 31 new compounds designed, synthesized and evaluated on Bcr-Abl, BTK and FLT3-ITD as part of our program to develop 2,6,9-trisubstituted purine derivatives as inhibitors of oncogenic kinases.
Jeanluc Bertrand   +10 more
doaj   +2 more sources

Glutathione-Mediated Neuroprotective Effect of Purine Derivatives [PDF]

open access: yesInternational Journal of Molecular Sciences, 2023
Nobuko Matsumura, Koji Aoyama
exaly   +2 more sources

Synthesis of 6-Alkynylated Purine-Containing DNA via On-Column Sonogashira Coupling and Investigation of Their Base-Pairing Properties

open access: yesMolecules, 2023
Synthetic unnatural base pairs have been proven to be attractive tools for the development of DNA-based biotechnology. Our group has very recently reported on alkynylated purine–pyridazine pairs, which exhibit selective and stable base-pairing via ...
Hidenori Okamura   +4 more
doaj   +1 more source

Total synthesis of [15N]-labelled C6-substituted purines from [15N]-formamide—easy preparation of isotopically labelled cytokinins and derivatives [PDF]

open access: yesRoyal Society Open Science, 2018
Cytokinins (CKs) and their metabolites and derivatives are essential for cell division, plant growth regulation and development. They are typically found at minute concentrations in plant tissues containing very complicated biological matrices. Therefore,
Jan Buček   +7 more
doaj   +1 more source

The effects of seasonal variation on the microbial-n flow to the small intestine and prediction of feed intake in grazing karayaka sheep [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2013
The objectives of the present study were to estimate the microbial-N flow to the small intestine and to predict the digestible organic matter intake (DOMI) in grazing Karayaka sheep based on urinary excretion of purine derivatives (xanthine, hypoxanthine,
SALMAN M, CETINKAYA N, SELCUK Z, GENC B
doaj   +1 more source

Molecular modeling and quantitative structure–property relationships (QSPRs) of purine derivatives as corrosion inhibitor in acid medium

open access: yesScientific African, 2020
The corrosion inhibition potential of purine and its twelve derivatives was theoretically investigated. Their chemical descriptors: dipole moments, softness, electronegativity, chemical hardness, molecular weight in conjunction with the electronic ...
B.T. Ogunyemi, D.F. Latona, I.A. Adejoro
doaj   +1 more source

Assessing Meat Freshness via Nanotechnology Biosensors: Is the World Prepared for Lightning-Fast Pace Methods?

open access: yesBiosensors, 2023
In the rapidly evolving field of food science, nanotechnology-based biosensors are one of the most intriguing techniques for tracking meat freshness.
Wen Xia Ling Felicia   +5 more
doaj   +1 more source

Creatinine and purine derivatives excretion and microbial synthesis in lambs fed rain tree pod meal

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022
Evaluated the levels of rain tree (Samanea saman) pod meal (RTPM) (0, 10, 15, 20 and 25%) replacing maize in the dry matter of the diet on intake of DM, CP and ME, creatinine and total purine derivatives excretion in urine and microbial protein synthesis
L.B. Sousa   +8 more
doaj   +1 more source

Functionalized Solid Electrodes for Electrochemical Biosensing of Purine Nucleobases and Their Analogues: A Review

open access: yesSensors, 2015
Interest in electrochemical analysis of purine nucleobases and few other important purine derivatives has been growing rapidly. Over the period of the past decade, the design of electrochemical biosensors has been focused on achieving high sensitivity ...
Vimal Kumar Sharma   +2 more
doaj   +1 more source

Níveis de uréia na ração de novilhos de quatro grupos genéticos: estimativa da produção de proteína microbiana por meio dos derivados de purinas na urina utilizando duas metodologias de coleta Urea levels in diet for steers of four genetic groups: microbial protein production by the urinary purine derivatives, using two collection methodologies

open access: yesRevista Brasileira de Zootecnia, 2008
Objetivou-se avaliar o efeito de quatro níveis de uréia na ração: 0; 0,65; 1,3 e 1,95% na matéria seca (MS), sobre a estimativa da produção de proteína microbiana por meio dos derivados de purinas na urina, em duas metodologias de coleta em novilhos de ...
Luciana Navajas Rennó   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy