Results 41 to 50 of about 677,954 (299)

Ammonification Process Is Limited by Transformation of Medium Molecular Weight Nitrogenous Organics but Not Hydrolysis of Proteins. [PDF]

Adv Sci (Weinh)
A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Li J, Qiu J, Lü F, Zhang H, He P.
europepmc   +2 more sources

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

1,2,3-Triazoles as leaving groups: SNAr reactions of 2,6-bistriazolylpurines with O- and C-nucleophiles

Beilstein Journal of Organic Chemistry, 2021
A new approach was designed for the synthesis of C6-substituted 2-triazolylpurine derivatives. A series of substituted products was obtained in SNAr reactions between 2,6-bistriazolylpurine derivatives and O- and C-nucleophiles under mild conditions. The
Dace Cīrule, Irina Novosjolova, Ērika Bizdēna, Māris Turks   +3 more
doaj   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Evaluation of methodologies of urine collection to estimate microbial synthesis in bovines diets containing or not containing lipids

Bioscience Journal, 2020
This study investigated the effectiveness of the urine sample collection method in predicting the volume urinary and synthesis of microbial nitrogen. Eight fistulated steers were used with accessible rumens and kept in individual stalls.
Laila Cecília Ramos Bendia, Carlos Augusto de Alencar Fontes, Elizabeth Fonsêca Processi, Clóvis Carlos Silveira Filho, Cláudio Teixeira Lombardi, Paulo Roberto Silveira Pimentel, Ronaldo Lopes Oliveira, Leilson Rocha Bezerra, Tiago Cunha Rocha   +8 more
doaj   +3 more sources

Effects of theophylline on ADCY5 activation-From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients.

PLoS ONE, 2023
We show the effects of the three purine derivatives, caffeine, theophylline, and istradefylline, on cAMP production by adenylyl cyclase 5 (ADCY5)-overexpressing cell lines.
Dirk Tänzler, Marc Kipping, Marcell Lederer, Wiebke F Günther, Christian Arlt, Stefan Hüttelmaier, Andreas Merkenschlager, Andrea Sinz   +7 more
doaj   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Synthesis and characterization of novel PIPERIDINYL-methyl-PURINEAMINE derivatives

Results in Chemistry
Piperidinyl methyl purine amines are the biologically active compounds, which exhibit different biological activities; we here in reported the purine amine derivatives from bromo fluoro isonicotinate in six steps, which involves, Suzuki coupling, SNAr ...
Srinivasa Reddy Keesara, Ratnasekhar Bolla, Hanumantharayappa Bharathkumar, Ramya Chilukuri, Sreedhar Gundekari, Mohan Varkolu   +5 more
doaj   +1 more source

Recovery of intravenously infused chromium EDTA and lithium sulphate in the urine of cattle and their use as markers to measure urine volume

Animal, 2009
A series of metabolism experiments investigated the recovery of continuous-, intravenously infused chromium complexed with ethylenediamine tetra-acetic acid (CrEDTA) and lithium sulphate in the urine of cattle with a view to using the markers to estimate
M.K. Bowen, D.P. Poppi, S.R. McLennan
doaj   +1 more source

Purine And Pyrimidine Salvage Pathway In Thermophiles: A Valuable Source Of Biocatalysts For The Industrial Production Of Nucleic Acid Derivatives [PDF]

, 2018
Due to their similarity to natural counterparts, nucleic acid derivatives (nucleobases, nucleosides, and nucleotides, among others) are interesting molecules for pharmaceutical, biomedical, or food industries.
Del Arco, Jon, Fernandez Lucas, Jesus, Arco Arrieta, Jon del   +2 more
core   +1 more source