Nucleophilic Arylation of Halopurines Facilitated by Brønsted Acid in Fluoroalcohol
Molecules, 2019 Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalcohol.
Naoko Takenaga +7 more
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Determination of association constants between 5 '-guanosine monophosphate gel and aromatic compounds by capillary electrophoresis [PDF]
, 2013 Hydro gel formed by 5'-guanosine monophosphate (GMP) in the presence of a potassium ion is expected to exhibit interesting selectivity in capillary electrophoretic separations.
Alberty +32 more
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Investigation of 8-Aza-7-Deaza Purine Nucleoside Derivatives
Molecules, 2019 Glycosylation of 6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine and its iodo- and bromo- analogues with the protected ribofuranose and 2′-deoxyribofuranose under different conditions resulted in the synthesis of N9- and N8-glycosylated purine ...
Hang Ren, Haoyun An, Jingchao Tao
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ZZE-Configuration of chromophore ß-153 in C-phycocyanin from Mastigocladus laminosus [PDF]
, 1987 The photochemistry of C-phycocyanin has been studied after denaturation in the dark. It shows an irreversible reaction which has characteristics of a Ζ,Ζ,Ε- to Z,Z,Z-isomerization of dihydrobilins. Its amplitude depends on the reaction conditions, with
Bode, W. +7 more
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Search of protein kinase CK2 inhibitors based on purine-2,6-diones derivatives [PDF]
The Ukrainian Biochemical Journal, 2017 This work is aimed to the search of protein kinase CK2 inhibitors among the purine-2,6-dione derivatives by molecular docking and biochemical tests. It was found that the most active compound 8-[2-[(3-methoxyphenyl)methylidene]hydrazine-1-yl]-3-methyl-7-(
M. V. Protopopov +6 more
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A repurposing strategy for Hsp90 inhibitors demonstrates their potency against filarial nematodes [PDF]
, 2014 Novel drugs are required for the elimination of infections caused by filarial worms, as most commonly used drugs largely target the microfilariae or first stage larvae of these infections.
AL Petersen +46 more
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Effect of adenine on the synthesis of purine derivatives in wheat seedlings
Acta Societatis Botanicorum Poloniae, 2015 The effect of adenine and other purine derivatives on the "de novo" purine synthesis was investigated in young wheat schoots. Adenine, adenosine and AMP inhibited strongly this biosynthesis, whereas hypoxanthine had no effect.
Hanna Rybacka
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Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release. [PDF]
, 2018 Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs).
Clementi, Nina +11 more
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Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region
Molecules, 2005 Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. Theabsorption spectrum of some 5-substituted derivatives was found to extend to the visibleregion.
Jacek Wierzchowski +2 more
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, 1974 The origin of life is in a sense a genetic problem, for, as H. J. Muller pointed out many years ago, the essential attribute that identifies living matter is its capacity to replicate itself and its variants (1). Because this uniquely biological property
Horowitz, N. H., Hubbard, Jerry S.
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