Biosensor measurement of purine release from cerebellar cultures and slices [PDF]
, 2010 We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Eason, Robert +5 more
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Nucleophilic Arylation of Halopurines Facilitated by Brønsted Acid in Fluoroalcohol
Molecules, 2019 Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalcohol.
Naoko Takenaga +7 more
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Thermoanalytical study of purine derivatives compounds
Eclética Química, 2018 Thermal methods of analysis are now used in a very large range of scientific investigations. In this work simultaneous thermogravimetry-differential thermal analysis (TG-DTA), X-Ray powder diffractometry and infrared spectroscopy were used to study the ...
G. F. C. Sotelo +2 more
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Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation [PDF]
, 2011 Background: The essential purine salvage pathway of Trypanosoma brucei bears interesting catalytic enzymes for chemotherapeutic intervention of Human African Trypanosomiasis.
Jason Greenwald +17 more
core +2 more sources
Investigation of 8-Aza-7-Deaza Purine Nucleoside Derivatives
Molecules, 2019 Glycosylation of 6-amino-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine and its iodo- and bromo- analogues with the protected ribofuranose and 2′-deoxyribofuranose under different conditions resulted in the synthesis of N9- and N8-glycosylated purine ...
Hang Ren, Haoyun An, Jingchao Tao
doaj +1 more source
Search of protein kinase CK2 inhibitors based on purine-2,6-diones derivatives [PDF]
The Ukrainian Biochemical Journal, 2017 This work is aimed to the search of protein kinase CK2 inhibitors among the purine-2,6-dione derivatives by molecular docking and biochemical tests. It was found that the most active compound 8-[2-[(3-methoxyphenyl)methylidene]hydrazine-1-yl]-3-methyl-7-(
M. V. Protopopov +6 more
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Effect of adenine on the synthesis of purine derivatives in wheat seedlings
Acta Societatis Botanicorum Poloniae, 2015 The effect of adenine and other purine derivatives on the "de novo" purine synthesis was investigated in young wheat schoots. Adenine, adenosine and AMP inhibited strongly this biosynthesis, whereas hypoxanthine had no effect.
Hanna Rybacka
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Stereospecific alkylation of substituted adenines by the Mitsunobu coupling reaction under microwave-assisted conditions† [PDF]
RSC Advances, 2014 A novel and efficient synthetic method has been developed for the preparation of alkylated aminopurines (N,N-dimethyl-, 2-chloro-N-methyl-, and N-methyladenines) with achiral and chiral 3,4-dihydro-2H-1,5-benzoxathiepin-3-ol by the Mitsunobu reaction ...
M. E. García-Rubiño +5 more
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Pyrazolo[4,3-e][1,2,4]triazines: Purine Analogues with Electronic Absorption in the Visible Region
Molecules, 2005 Synthesis of several pryrazolo[4,3-e][1,2,4]-triazines is described. Theabsorption spectrum of some 5-substituted derivatives was found to extend to the visibleregion.
Jacek Wierzchowski +2 more
doaj +1 more source
The Utilization of Coconut Coir as Supplementary Feed for Beef Cattle Production
Caraka Tani: Journal of Sustainable Agriculture, 2022 High feed price is a major problem in the production of beef cattle. Therefore, this study aims to determine coconut coir's technical and economic potential for beef cattle feed.
Limbang Kustiawan Nuswantara +3 more
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