Results 141 to 150 of about 61,638 (306)

A modular minimal cell model: Purine and pyrimidine transport and metabolism [PDF]

, 2004
Mariajosé Castellanos, Darcy B. Wilson, Michael L. Shuler   +2 more
openalex   +1 more source

An Investigation of TDA1 Deficiency in Saccharomyces cerevisiae During Diauxic Growth

Yeast, EarlyView.
Tda1p is a protein kinase in Saccharomyces cerevisiae with unknown/disputed function. Its role during the diauxic shift was investigated in three independent transcriptomics experiment. From the evidence that was consistent across the experiments, we propose that TDA1 is involved in regulation of mitochondrial translation by repressing the expression ...
Erik Y. Bjurström, Praphapan Lasin, Daniel Brunnsåker, Ievgeniia A. Tiukova, Ross D. King   +4 more
wiley   +1 more source

Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN. [PDF]

Cancer Med
Jiang Y, Xiao H, Yang Y, Chen G, Zhang Y, Wu X, Zhang Q, Huang Q, Gao H, Han Y, Zhang A, Jiang D, Zheng L, Li Y, Gao Y.   +14 more
europepmc   +1 more source

Purine and pyrimidine metabolism by estuarine bacteria [PDF]

, 2006
GM Berg, NOG Jørgensen
openalex   +1 more source

An integrative strategy used by the aphid Uroleucon formosanum to counter host sesquiterpene lactone defense: Insights from combined genomic and transcriptomic analysis

Insect Science, EarlyView.
We report the first high‐quality chromosome‐level genome assembly for the aphid Uroleucon formosanum, a serious pest that infests lettuce in eastern Asia. A combination of comparative genomic analyses and RNA‐seq transcriptome profiling suggests that U. formosanum employs integrative mechanisms to cope with host plant‐derived sesquiterpene lactone (STL)
Jing‐Bo Li, Li‐Yun Jiang, Ge‐Xia Qiao, Jing Chen   +3 more
wiley   +1 more source

Purine Metabolism Pathway Influence on Running Capacity in Rats. [PDF]

Metabolites
Chen D, Biney CN, Wang Q, Cai M, Cheng S, Chen W, Zhang J, Zhao J, Zhang Y, Zhang W.   +9 more
europepmc   +1 more source

Comprehensive Detection of Disorders of Purine and Pyrimidine Metabolism by HPLC with Electrospray Ionization Tandem Mass Spectrometry [PDF]

, 2006
S. Hartmann, Jürgen G. Okun, Christiane Schmidt, Claus‐Dieter Langhans, Sven F. Garbade, Peter Burgard, Dorothea Haas, Jörn Oliver Sass, William L. Nyhan, Georg F. Hoffmann   +9 more
openalex   +1 more source

Purine and Pyrimidine Metabolism [PDF]

Journal of Clinical Pathology, 1977
openaire   +2 more sources

A Xanthine Derivative With Novel Heat Shock Protein 90‐Alpha Inhibitory and Senolytic Properties

Aging Cell, EarlyView.
This study aimed to find safe senolytic drugs that selectively eliminate senescent cells. Focusing on HSP90 inhibitors, we employed a virtual screening to identify novel, safer compounds (A). K5, a xanthinic candidate, effectively eliminated senescent cells in various cellular models (B), extended lifespan in flies, and reduced aging signs in mice (C).
Sandra Atlante, Luca Cis, Davide Pirolli, Michela Gottardi Zamperla, Veronica Barbi, Antonello Mai, Clemens Zwergel, Serena Marcozzi, Maria Elisa Giuliani, Giorgia Bigossi, Giovanni Lai, Fiorenza Orlando, Robertina Giacconi, Fabrizia Lattanzio, Giulia Matacchione, Chiara Giordani, Massimo Bracci, Fabiola Olivieri, Federico Boschi, Paola Tabarelli De Fatis, Giovanni Battista Ivaldi, Marco Malavolta, Antonella Farsetti, Maria Cristina De Rosa, Carlo Gaetano   +24 more
wiley   +1 more source

Purine metabolism rewiring improves glioblastoma susceptibility to temozolomide treatment. [PDF]

Cell Death Dis
D'Aprile S, Denaro S, Torrisi F, Longhitano L, Giallongo S, Giallongo C, Bontempi V, Bucolo C, Drago F, Mione MC, Li Volti G, Potokar M, Jorgačevski J, Zorec R, Tibullo D, Amorini AM, Vicario N, Parenti R.   +17 more
europepmc   +1 more source