Results 141 to 150 of about 1,297,457 (342)
PLACENTAL FEEDING AND PURINE METABOLISM
Victor John Harding, E. Gordon Young
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Abstract Objectives Pediatric acute pancreatitis (AP) is associated with gut dysbiosis. We aimed to determine if dysbiosis persisted during follow‐up and whether it is associated with clinical outcomes. Methods Prospective enrollment of participants <21 years with first AP.
Chinenye R. Dike+12 more
wiley +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
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Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteria
Purines and their derivatives control intracellular energy homeostasis and nucleotide synthesis, and act as signaling molecules. Here, we combine structural and sequence information to define a purine-binding motif that is present in sensor domains of ...
Elizabet Monteagudo-Cascales+6 more
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IV. An Improved Separation Method for Twenty two Compounds Related to Purine and 6-Thiopurine Metabolism Using High-Pressure Liquid Cation-Exchange Chromatography [PDF]
Hans-Joachim Breter
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Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik+6 more
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PURINE METABOLISM IN THERAPY OF VON GIERKE'S DISEASE [PDF]
Paul J. Benke, Scott Gold, Uwe Stave
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THE RELATIONSHIP OF FOLIC ACID TO FORMATE METABOLISM IN THE RAT: FORMATE INCORPORATION INTO PURINES
George R. Drysdale+2 more
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ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao+6 more
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