Results 141 to 150 of about 1,297,457 (342)

PLACENTAL FEEDING AND PURINE METABOLISM

open access: hybrid, 1919
Victor John Harding, E. Gordon Young
openalex   +1 more source

Acute pancreatitis gut dysbiosis persists at 1‐year follow‐up and is associated with clinical outcomes

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric acute pancreatitis (AP) is associated with gut dysbiosis. We aimed to determine if dysbiosis persisted during follow‐up and whether it is associated with clinical outcomes. Methods Prospective enrollment of participants <21 years with first AP.
Chinenye R. Dike   +12 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteria

open access: yesNature Communications
Purines and their derivatives control intracellular energy homeostasis and nucleotide synthesis, and act as signaling molecules. Here, we combine structural and sequence information to define a purine-binding motif that is present in sensor domains of ...
Elizabet Monteagudo-Cascales   +6 more
doaj   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik   +6 more
wiley   +1 more source

PURINE METABOLISM IN THERAPY OF VON GIERKE'S DISEASE [PDF]

open access: bronze, 1977
Paul J. Benke, Scott Gold, Uwe Stave
openalex   +1 more source

Oligodendrocyte Precursor Cells in Demyelination Repair: Mechanisms, Crosstalk, and Therapeutic Frontiers

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao   +6 more
wiley   +1 more source

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