Emerging roles for integrated stress response signaling in homeostasis
The FEBS Journal, EarlyView.Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar +2 more
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Identification of molecular subtypes and a prognostic signature based on machine learning and purine metabolism-related genes in breast cancer. [PDF]
Medicine (Baltimore)Huang W, Tang P, Mei J, Zhang Z, Lu G.
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Development and validation of prognostic index based on purine metabolism genes in patients with bladder cancer. [PDF]
Front Med (Lausanne), 2023 Wu Z, Feng Z, Wei H, Lin C, Chen K.
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The metabolism of the purines in man
Experimental Biology and Medicine, 1910 L. B. Mendel, J. F. Lyman
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A STUDY OF THE METABOLISM OF PURINE RIBOSIDE [PDF]
Journal of Biological Chemistry, 1956 George Bosworth Brown, Milton P. Gordon
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Deregulation of purine metabolism in Alzheimer's disease [PDF]
, 2014 Belén Ansoleaga +8 more
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The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles
Insect Molecular Biology, EarlyView.Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork +3 more
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Unveiling purine metabolism dysregulation orchestrated immunosuppression in advanced pancreatic cancer and concentrating on the central role of NT5E. [PDF]
Front ImmunolZhang J, Zhang X, Wu R, Dong CS.
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Purine metabolism abnormalities in a hyperuricosuric subclass of autism
, 2000 Theodore Page, Mary Coleman
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Journal of Microscopy, EarlyView.Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson +2 more
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