Results 201 to 210 of about 72,751 (304)

Table S8 from <i>De Novo</i> Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression

Naveen Kumar Tangudu, Raquel Buj, Hui Wang, Jiefei Wang, Aidan R. Cole, Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang, Adam Chatoff, Claudia V. Crispim, Peter Sajjakulnukit, Maureen A. Lyons, Kristine Cooper, Nadine Hempel, Costas A. Lyssiotis, Uma Chandran, Nathaniel W. Snyder, Katherine M. Aird   +18 more
openalex   +1 more source

THE RELATIONSHIP OF FOLIC ACID TO FORMATE METABOLISM IN THE RAT: FORMATE INCORPORATION INTO PURINES

, 1951
George R. Drysdale, G.W.E. Plaut, Henry A. Lardy   +2 more
openalex   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

Photochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes, Fernanda M. Prado, Helena C. Junqueira, Marisa H. G. Medeiros, Graziella E Ronsein, Jean Cadet, Paolo Di Mascio   +6 more
wiley   +1 more source

<i>Isodon lophanthoides</i> alleviates liver fibrosis via modulation of purine metabolism and NF-κB signaling pathway: insights from multi-omics analysis. [PDF]

Front Pharmacol
Chen K, Liang J, Tan Y, Li Y, Pan X, Guo Z, Zhang W, Sun Z.   +7 more
europepmc   +1 more source

Geographic provenance and environmental growing conditions as factors influencing phytochemical composition of Arabica green coffee beans

Plant Biology, EarlyView.
Growth environment strongly influences green coffee bean biochemistry, linking phytochemical composition to adaptation under abiotic stress. Abstract This study explores how bioactive compounds in green coffee beans (Coffea arabica L.) vary across different geographic regions, addressing the key question of how environmental factors shape coffee ...
I. Pettazzoni, G. Benati, S. Monari, E. De Angelis, L. Navarini, M. Ferri, A. Tassoni   +6 more
wiley   +1 more source

Uric Acid, the End-Product of Purine Metabolism, Mitigates Tau-Related Abnormalities: Comparison with DOT, a Non-Antibiotic Oxytetracycline Derivative. [PDF]

Biomolecules
Andretto de Mattos B, Tomas-Grau RH, Alves Fernandes TA, González-Lizárraga F, Tourville A, Ciss I, Brunel JM, Chehin R, Lannuzel A, Ferrié L, Raisman-Vozari R, Figadère B, Del Bel E, Michel PP.   +13 more
europepmc   +1 more source

The molecular landscape of polycystic kidneys is marked by common alterations in purine metabolism [PDF]

Jean-Paul Decuypere, Daniel Borràs, Priyanka Koshy, Ludwig Missiaen, Steffen Fieuws, Nikky Corthout, Humbert De Smedt, Diethard Monbaliu, Jacques Pirenne, Tania Roskams, Bart Ghesquière, Bert Bammens, Abhishek D. Garg, Djalila Mekahli, Rudi Vennekens   +14 more
openalex   +1 more source

Effect of prolonged voluntary wheel running on oxidative stress and defence mechanisms in cortex and hippocampus of healthy female rats

Experimental Physiology, EarlyView.
Abstract Physical exercise promotes brain health and cognitive function possibly through mechanisms that include strengthened resistance to oxidative stress. However, limited research has explored the cumulative effects of regular voluntary exercise on both oxidative stress and defence mechanisms in hippocampus and cortex, two regions essential for ...
Camilla Myrup Holst, Iria Esperon‐Abril, Frederik Bryske Juhl, Jesper Emil Jakobsgaard, Jonas B. Kristiansen, Kristian Vissing, Tinna Stevnsner   +6 more
wiley   +1 more source

Purinosomes and Purine Metabolism in Mammalian Neural Development: A Review. [PDF]

Acta Histochem Cytochem
Yamada S, Mizukoshi T, Sato A, Sakakibara SI.   +3 more
europepmc   +1 more source

Figure 5 from One-Carbon Metabolism Inhibition Depletes Purines and Results in Profound and Prolonged Ewing Sarcoma Growth Suppression

Sara Zirpoli, Noah Copperman, Shrey Patel, A.R.W. Forrest, Zhanjun Hou, Larry H. Matherly, David M. Loeb, Antonio Di Cristofano   +7 more
openalex   +1 more source