Results 201 to 210 of about 61,638 (306)

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury [PDF]

, 2018
Siobhan Crittenden, Ashleigh Cheyne, Alex Adams, Thorsten Forster, Calum T. Robb, Jennifer M. Felton, Gwo–Tzer Ho, Dominik Rückerl, Adriano G. Rossi, Stephen M. Anderton, Peter Ghazal, Jack Satsangi, Sarah Howie, Chengcan Yao   +13 more
openalex   +1 more source

Hyperuricaemia in type 1 Gaucher disease: is uric acid a biomarker for disease severity?

Internal Medicine Journal, EarlyView.
Abstract Background Elevated serum uric acid (SUA) levels were observed in Gaucher disease type 1 (GD1) patients followed for two decades in northern Israel. There are no previous reports regarding hyperuricaemia in GD1 patients. Aims We aimed to evaluate the frequency of hyperuricaemia in GD1 patients and its correlation to disease severity ...
Zufit Hexner‐Erlichman, Salmas Watad, Jeff Szer, Nayaf Habashi, Hanna Rosenbaum   +4 more
wiley   +1 more source

Purinosomes and Purine Metabolism in Mammalian Neural Development: A Review. [PDF]

Acta Histochem Cytochem
Yamada S, Mizukoshi T, Sato A, Sakakibara SI.   +3 more
europepmc   +1 more source

STUDIES OF PURINE METABOLISM

Cold Spring Harbor Symposia on Quantitative Biology, 1948
openaire   +2 more sources

Relationship of the intensity of physical performance and sedentary time with uric acid in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
High uric acid (UA) facilitates diabetes progression and is responsible for developing other diseases, such as cardiovascular disease and renal disease. Lifestyle modifications could lower UA levels, but relevant evidence is required in patients with type 2 diabetes.
Jie Li, Ertao Zhang, Zhao Dong, Yan Liu
wiley   +1 more source

Utilizing integrated bioinformatics and machine learning approaches to elucidate biomarkers linking sepsis to purine metabolism-associated genes. [PDF]

Sci Rep
Liang F, Zheng M, Lu J, Liu P, Chen X.
europepmc   +1 more source

Prospective association between plasma amino acids and healthy aging in older adults

Journal of Internal Medicine, EarlyView.
Abstract Background Most studies have compared plasma amino acids profiling across different age groups using a cross‐sectional design, but no previous research has assessed the relationship between specific amino acid species and healthy aging. Objectives This study aims to explore the relationship between plasma concentrations of nine amino acids and
Damián González‐Beltrán, Humberto Yévenes‐Briones, Alberto Lana, Juan Cárdenas‐Valladolid, Miguel Ángel Salinero‐Fort, Fernando Rodríguez‐Artalejo, Esther Lopez‐Garcia, Francisco Félix Caballero   +7 more
wiley   +1 more source

Pioglitazone-induced alterations of purine metabolism in healthy male subjects. [PDF]

Clin Transl Sci
Kang J, Li Y, Lee S, Yu KS, Cho JY.
europepmc   +1 more source

The TP53 tumor suppressor gene: From molecular biology to clinical investigations

Journal of Internal Medicine, EarlyView.
Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
wiley   +1 more source

Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer. [PDF]

Sci Signal
Cordova RA, Sommers NR, Law AS, Klunk AJ, Brady KE, Goodrich DW, Anthony TG, Brault JJ, Pili R, Wek RC, Staschke KA.   +10 more
europepmc   +1 more source